Miksoinflamatuar fibroblastik sarkom: Olgu sunumu

Öz

Miksoinflamatuar fibroblastik sarkom (MİFS), son zamanlarda tanımlanmış olan ve seyrek görülen, düşük dereceli bir sarkomdur. Genellikle alt veya üst ekstremitelerde yerleşen MİFS, klinikte iyi huylu kistik kitle bulgusu verirken fibroblastik miksoid stroma içerisinde iğsi ya da atipik görünümlü hücreler ile mikst türde inflamatuar infiltrattan oluşur. Radyolojik ve makroskobik görüntüsü genellikle düzensiz sınırlı lobüle kitle şeklindedir. Çalışmamızda, daha önceden tanımlanan özelliklerden farklı şekilde düzgün sınırlı ve sadece orta bölümde neoplastik hücreler saptanan tümöral bir kitle sunulmaktadır. Klinik olarak iyi huylu kitlelerden ayrılması oldukça zor olan MİFS olgularında, ekstremite yerleşimli lezyonlarda habaset olasılığı her zaman akılda bulundurulmalıdır.

Anahtar Kelimeler

• Lezyon; miksoid stroma; miksoinflamatuar fibroblastik sarkom; sarkom.

Myxoinflammatory fibroblastic sarcoma: a case report

Abstract

Myxoinflammatory fibroblastic sarcoma (MIFS) is a recently described, rare low-grade sarcoma. Generally located in the upper and lower extremities, MIFS clinically mimics a benign cystic mass and is composed of spindle-like or atypical cells and mixed inflammatory infiltrates located in the fibroblastic myxoid stroma. Radiologic images and macroscopic appearance generally resemble a lobulated mass with irregular margins. We present a case of a tumoral mass with neoplastic cells at the center and a smooth surface with a previously undefined appearance. Myxoinflammatory fibroblastic sarcoma is significantly difficult to distinguish clinically from benign lesions and the surgeon should consider the possibility of malignancy in lesions located at the extremities.

Keywords

• Lesion
• myxoid stroma
• myxoinflammatory fibroblastic sarcoma
• sarcoma

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