Gene therapy in sports medicine

Volume: 31 Number: 5 September 11, 2006
  • Christian Latermann
  • Semih Gur
  • Paul Robbins
  • Christopher Evans
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Acta Orthopaedica et Traumatologica Turcica
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Gene therapy in sports medicine

Abstract

Injured soft tissues trigger a cellular response which is necessary for recovery and regulated by specific proteins, namely growth factors like PDGF, TGF-B, BFGF, IGF-1 and BMP-2. Application of these factors via external route is not possible because of the very short half-life time. Thus, gene therapy with virus vectors is now being discussed to provide continuous growth factors. As briefly summarized in this review article experiments on animals and early results of clinical work and research demonstrate that it can be used in the treatment of sports injuries.

Keywords

Details

Primary Language

English

Subjects

-

Journal Section

-

Authors

Christian Latermann This is me

Semih Gur This is me

Paul Robbins This is me

Christopher Evans This is me

Publication Date

September 11, 2006

Submission Date

March 11, 2014

Acceptance Date

-

Published in Issue

Year 1997 Volume: 31 Number: 5

DOI

https://doi.org/10.3944/aott.v31i5.4257

IZ

https://izlik.org/JA32JS24PK

Cite

RIS / Bibtex
APA
Latermann, C., Gur, S., Robbins, P., & Evans, C. (2006). Gene therapy in sports medicine. Acta Orthopaedica et Traumatologica Turcica, 31(5), 502-505. https://doi.org/10.3944/aott.v31i5.4257
AMA
1.Latermann C, Gur S, Robbins P, Evans C. Gene therapy in sports medicine. Acta Orthopaedica et Traumatologica Turcica. 2006;31(5):502-505. doi:10.3944/aott.v31i5.4257
Chicago
Latermann, Christian, Semih Gur, Paul Robbins, and Christopher Evans. 2006. “Gene Therapy in Sports Medicine”. Acta Orthopaedica et Traumatologica Turcica 31 (5): 502-5. https://doi.org/10.3944/aott.v31i5.4257.
EndNote
Latermann C, Gur S, Robbins P, Evans C (September 1, 2006) Gene therapy in sports medicine. Acta Orthopaedica et Traumatologica Turcica 31 5 502–505.
IEEE
[1]C. Latermann, S. Gur, P. Robbins, and C. Evans, “Gene therapy in sports medicine”, Acta Orthopaedica et Traumatologica Turcica, vol. 31, no. 5, pp. 502–505, Sept. 2006, doi: 10.3944/aott.v31i5.4257.
ISNAD
Latermann, Christian - Gur, Semih - Robbins, Paul - Evans, Christopher. “Gene Therapy in Sports Medicine”. Acta Orthopaedica et Traumatologica Turcica 31/5 (September 1, 2006): 502-505. https://doi.org/10.3944/aott.v31i5.4257.
JAMA
1.Latermann C, Gur S, Robbins P, Evans C. Gene therapy in sports medicine. Acta Orthopaedica et Traumatologica Turcica. 2006;31:502–505.
MLA
Latermann, Christian, et al. “Gene Therapy in Sports Medicine”. Acta Orthopaedica et Traumatologica Turcica, vol. 31, no. 5, Sept. 2006, pp. 502-5, doi:10.3944/aott.v31i5.4257.
Vancouver
1.Christian Latermann, Semih Gur, Paul Robbins, Christopher Evans. Gene therapy in sports medicine. Acta Orthopaedica et Traumatologica Turcica. 2006 Sep. 1;31(5):502-5. doi:10.3944/aott.v31i5.4257