Research Article

Arthroplasty for the treatment of joint degeneration caused by ochronosis in two cases

Volume: 42 Number: 2 June 12, 2008
  • Mehmet Kefeli
  • Yilmaz Tomak
  • Bilge Can
  • Sancar Baris
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Acta Orthopaedica et Traumatologica Turcica
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Arthroplasty for the treatment of joint degeneration caused by ochronosis in two cases

Abstract

Ochronosis is a rare metabolic disease caused by the deficiency of the homogentisic acid oxidase enzyme. With increasing age, accumulation of pigment deposits of homogentisic acid in the joint cartilage results in ochronotic osteoarthritis. We presented two female patients, with ages 55 and 60 years, who underwent staged bilateral uncemented total hip and bilateral cemented total knee arthroplasty, respectively, for osteoarthritis caused by ochronosis. Both patients had no significant complaints at final follow-up examinations made 12 months and 10 months after the second operation in the hip and knee, respectively. Plain radiographs did not show any abnormality in the components of the prostheses. Histopathologic examination of surgical specimens showed brown-black pigment deposits in the connective tissue and cartilage tissue. Key words: Alkaptonuria/complications; arthroplasty, replacement, hip; arthroplasty, replacement, knee; ochronosis/complications; osteoarthritis/etiology.

Keywords

Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Mehmet Kefeli This is me

Yilmaz Tomak This is me

Bilge Can This is me

Sancar Baris This is me

Publication Date

June 12, 2008

Submission Date

May 10, 2014

Acceptance Date

-

Published in Issue

Year 2008 Volume: 42 Number: 2

IZ

https://izlik.org/JA63BY74MH

Cite

RIS / Bibtex
APA
Kefeli, M., Tomak, Y., Can, B., & Baris, S. (2008). Arthroplasty for the treatment of joint degeneration caused by ochronosis in two cases. Acta Orthopaedica et Traumatologica Turcica, 42(2), 139-144. https://izlik.org/JA63BY74MH
AMA
1.Kefeli M, Tomak Y, Can B, Baris S. Arthroplasty for the treatment of joint degeneration caused by ochronosis in two cases. Acta Orthopaedica et Traumatologica Turcica. 2008;42(2):139-144. https://izlik.org/JA63BY74MH
Chicago
Kefeli, Mehmet, Yilmaz Tomak, Bilge Can, and Sancar Baris. 2008. “Arthroplasty for the Treatment of Joint Degeneration Caused by Ochronosis in Two Cases”. Acta Orthopaedica et Traumatologica Turcica 42 (2): 139-44. https://izlik.org/JA63BY74MH.
EndNote
Kefeli M, Tomak Y, Can B, Baris S (June 1, 2008) Arthroplasty for the treatment of joint degeneration caused by ochronosis in two cases. Acta Orthopaedica et Traumatologica Turcica 42 2 139–144.
IEEE
[1]M. Kefeli, Y. Tomak, B. Can, and S. Baris, “Arthroplasty for the treatment of joint degeneration caused by ochronosis in two cases”, Acta Orthopaedica et Traumatologica Turcica, vol. 42, no. 2, pp. 139–144, June 2008, [Online]. Available: https://izlik.org/JA63BY74MH
ISNAD
Kefeli, Mehmet - Tomak, Yilmaz - Can, Bilge - Baris, Sancar. “Arthroplasty for the Treatment of Joint Degeneration Caused by Ochronosis in Two Cases”. Acta Orthopaedica et Traumatologica Turcica 42/2 (June 1, 2008): 139-144. https://izlik.org/JA63BY74MH.
JAMA
1.Kefeli M, Tomak Y, Can B, Baris S. Arthroplasty for the treatment of joint degeneration caused by ochronosis in two cases. Acta Orthopaedica et Traumatologica Turcica. 2008;42:139–144.
MLA
Kefeli, Mehmet, et al. “Arthroplasty for the Treatment of Joint Degeneration Caused by Ochronosis in Two Cases”. Acta Orthopaedica et Traumatologica Turcica, vol. 42, no. 2, June 2008, pp. 139-44, https://izlik.org/JA63BY74MH.
Vancouver
1.Mehmet Kefeli, Yilmaz Tomak, Bilge Can, Sancar Baris. Arthroplasty for the treatment of joint degeneration caused by ochronosis in two cases. Acta Orthopaedica et Traumatologica Turcica [Internet]. 2008 Jun. 1;42(2):139-44. Available from: https://izlik.org/JA63BY74MH