Research Article

Autosomal dominant inheritance of congenital dislocation of the hip in 16 members of a family

Volume: 42 Number: 4 December 18, 2008
  • Gülay Ceylaner
  • Serdar Ceylaner
  • Fulya Üstünkan
  • Muharrem İnan
Acta Orthopaedica et Traumatologica Turcica Cover
Acta Orthopaedica et Traumatologica Turcica
PDF Download
EN TR

Autosomal dominant inheritance of congenital dislocation of the hip in 16 members of a family

Abstract

The effect of genetic factors on hip dislocation, acetabular dysplasia, and developmental dysplasia of the hip (DDH) has long been recognized. In this report, we presented a large family that showed single gene inheritance for DDH. Pedigree analysis of a pregnant woman revealed a history of DDH in 16 members of the family. Although the pedigree showed autosomal dominant inheritance with reduced penetrance, the prevalence of DDH was considerably high, almost accounting for one-third of the family members, and skipping only one generation. Of 16 cases, three patients were diagnosed at our center. The remaining 13 patients were diagnosed at other centers. Dislocation was diagnosed very late in most of the family members, while four cases were diagnosed at birth. All family members were informed by a detailed clinical letter and recommended evaluation for DDH at every birth.

Keywords

Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Gülay Ceylaner This is me

Serdar Ceylaner This is me

Fulya Üstünkan This is me

Muharrem İnan This is me

Publication Date

December 18, 2008

Submission Date

May 10, 2014

Acceptance Date

-

Published in Issue

Year 2008 Volume: 42 Number: 4

IZ

https://izlik.org/JA22HS57GZ

Cite

RIS / Bibtex
APA
Ceylaner, G., Ceylaner, S., Üstünkan, F., & İnan, M. (2008). Autosomal dominant inheritance of congenital dislocation of the hip in 16 members of a family. Acta Orthopaedica et Traumatologica Turcica, 42(4), 289-291. https://izlik.org/JA22HS57GZ
AMA
1.Ceylaner G, Ceylaner S, Üstünkan F, İnan M. Autosomal dominant inheritance of congenital dislocation of the hip in 16 members of a family. Acta Orthopaedica et Traumatologica Turcica. 2008;42(4):289-291. https://izlik.org/JA22HS57GZ
Chicago
Ceylaner, Gülay, Serdar Ceylaner, Fulya Üstünkan, and Muharrem İnan. 2008. “Autosomal Dominant Inheritance of Congenital Dislocation of the Hip in 16 Members of a Family”. Acta Orthopaedica et Traumatologica Turcica 42 (4): 289-91. https://izlik.org/JA22HS57GZ.
EndNote
Ceylaner G, Ceylaner S, Üstünkan F, İnan M (December 1, 2008) Autosomal dominant inheritance of congenital dislocation of the hip in 16 members of a family. Acta Orthopaedica et Traumatologica Turcica 42 4 289–291.
IEEE
[1]G. Ceylaner, S. Ceylaner, F. Üstünkan, and M. İnan, “Autosomal dominant inheritance of congenital dislocation of the hip in 16 members of a family”, Acta Orthopaedica et Traumatologica Turcica, vol. 42, no. 4, pp. 289–291, Dec. 2008, [Online]. Available: https://izlik.org/JA22HS57GZ
ISNAD
Ceylaner, Gülay - Ceylaner, Serdar - Üstünkan, Fulya - İnan, Muharrem. “Autosomal Dominant Inheritance of Congenital Dislocation of the Hip in 16 Members of a Family”. Acta Orthopaedica et Traumatologica Turcica 42/4 (December 1, 2008): 289-291. https://izlik.org/JA22HS57GZ.
JAMA
1.Ceylaner G, Ceylaner S, Üstünkan F, İnan M. Autosomal dominant inheritance of congenital dislocation of the hip in 16 members of a family. Acta Orthopaedica et Traumatologica Turcica. 2008;42:289–291.
MLA
Ceylaner, Gülay, et al. “Autosomal Dominant Inheritance of Congenital Dislocation of the Hip in 16 Members of a Family”. Acta Orthopaedica et Traumatologica Turcica, vol. 42, no. 4, Dec. 2008, pp. 289-91, https://izlik.org/JA22HS57GZ.
Vancouver
1.Gülay Ceylaner, Serdar Ceylaner, Fulya Üstünkan, Muharrem İnan. Autosomal dominant inheritance of congenital dislocation of the hip in 16 members of a family. Acta Orthopaedica et Traumatologica Turcica [Internet]. 2008 Dec. 1;42(4):289-91. Available from: https://izlik.org/JA22HS57GZ