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Kemik delmenin lokal sıcaklık ve kemik rejenerasyonu üzerine etkisi: In vivo çalışma

Year 2014, , 326 - 332, 30.05.2014
https://doi.org/10.3944/AOTT.2014.3074

Abstract

Amaç:Bu çalışmada kemik delme işleminin lokal kemik ısısı ve kemik rejenerasyonu üzerindeki etkilerinin saptanması ve optimal delme hızı ve basınç kuvvetinin bir hayvan modelinde belirlenmesi amaçlandı.

Çalışma planı: Çalışmaya iskelet gelişimini tamamlamış 12 adet Yeni Zelanda beyaz tavşanı katıldı. Tavşanların ağırlığı 2.8 ile 3.2 kg arasında değişmekteydi. Tavşanlar 2 gruba ayrılarak, 21. ve 42. gün sonunda ötenazi ile sakrifiye edildiler. Her iki grup için aynı delme protokolü kullanıldı. Tavşanların tibiasında 3 farklı basınç kuvveti (5, 10 ve 20 N) ve 3 farklı delme hızı (230, 370 ve 570 d/d) ile 3 delik açıldı. Delme sırasında oluşan bölgesel ısı kaydedildi. Daha sonra, tavşanların kemik rejenerasyonu histopatolojik çalışmalar ile incelendi.

Bulgular: Kemik ısısı delme süresi ve derinliğine bağlı değişim gösterdi. Yüksek delme hızına kıyasla düşük hızlarda kemik ısısının azaldığı ve kemik rejenerasyonun daha iyi olduğu gözlendi. Matkap uçlarındaki titanyum boron nitrit kaplamanın kemik ısısı ve yapısına etki etmediği saptandı. En iyi kemik rejenerasyonunun 230 d/d ve 20 N ile delme işleminin gerçekleştirildiği B Grubu tavşanlarda olduğu görüldü.

Çıkarımlar: Daha düşük devirde ve daha yüksek basınçla delme ile daha iyi kemik rejenerasyonu elde edilmektedir. Çalışma sonuçlarımıza göre optimal delme hızı 230 d/d ve basıncı 20 N idi.

References

  • Augustin G, Zigman T, Davila S, Udilljak T, Staroveski T, Brezak D, et al. Cortical bone drilling and thermal osteonecrosis. Clin Biomech (Bristol, Avon) 2012;27:313-25.
  • Harder S, Egert C, Wenz HJ, Jochens A, Kern M. Influence of the drill material and method of cooling on the development of intrabony temperature during preparation of the site of an implant. Br J Oral Maxillofac Surg 2013;51:74-8.
  • Karmani S. The thermal properties of bone and the effects of surgical intervention. Curr Orthop 2006;20:52-8.
  • Reingewirtz Y, Szmukler-Moncler S, Senger B. Influence of different parameters on bone heating and drilling time in implantology. Clin Oral Implants Res 1997;8:189-97.
  • Karunakar MA, Frankenburg EP, Le TT, Hall J. The thermal effects of intramedullary reaming. J Orthop Trauma 2004;18:674-9.
  • Monfoulet L, Rabier B, Chassande O, Fricain JC. Drilled hole defects in mouse femur as models of intramembranous cortical and cancellous bone regeneration. Calcif Tissue Int 2010;86:72-81.
  • Eriksson AR, Albrektsson T. Temperature threshold levels for heat-induced bone tissue injury: a vital-microscopic study in the rabbit. J Prosthet Dent 1983;50:101-7.
  • Sugita N, Osa T, Mitsuishi M. Analysis and estimation of cutting-temperature distribution during end milling in relation to orthopedic surgery. Med Eng Phys 2009;31:101
  • Shin HC, Yoon YS. Bone temperature estimation during orthopaedic round bur milling operations. J Biomech 2006;39:33-9.
  • Augustin G, Davila S, Mihoci K, Udiljak T, Vedrina DS, Antabak A. Thermal osteonecrosis and bone drilling parameters revisited. Arch Orthop Trauma Surg 2008;128:71-7.
  • Tu YK, Tsai HH, Lin LC. Finite element simulation of drill bit and bone thermal contact during drilling. The 2nd Int. Conf., May 16-18, 2008. Bioinform Biomed Eng 2008;71:1268.
  • Aslan A, Vatansever HS, Aslan GG, Eskiizmir G, Giray G. Effect of thermal energy produced by drilling on the facial nerve: histopathologic evaluation in guinea pigs. J Laryngol Otol 2005;119:600-5.
  • Denis K, Ham GV, Sloten JV. Influence of bone milling parameters on the temperature rise, milling forces and surface flatness in view of robot assisted total knee arthroplasty. Int Congr Series 2001;1230:300-6.
  • Bachus KN, Rondina MT, Hutchinson DT. The effects of drilling force on cortical temperatures and their duration: an in vitro study. Med Eng Phys 2000;22:685-91.
  • Sharawy M, Misch CE, Weller N, Tehemar S. Heat generation during implant drilling: the significance of motor speed. J Oral Maxillofac Surg 2002;60:1160-9.
  • Abouzgia MB, James DF. Measurements of shaft speed while drilling through bone. J Oral Maxillofac Surg 1995;53:1308-16.
  • Jacob CH, Berry JT. A study of the bone machining process--drilling. J Biomech 1976:343-9.
  • Karaca F, Aksakal B, Kom M. Influence of orthopaedic drilling parameters on temperature and histopathology of bovine tibia: an in vitro study. Med Eng Phys 2011;33:1221-7.
  • Sumer M, Misir AF, Telcioglu NT, Guler AU, Yenisey M. Comparison of heat generation during implant drilling using stainless steel and ceramic drills. J Oral Maxillofac Surg 2011;69:1350-4.

Effects of bone drilling on local temperature and bone regeneration: an in vivo study

Year 2014, , 326 - 332, 30.05.2014
https://doi.org/10.3944/AOTT.2014.3074

Abstract

Objective:The aim of this study was to examine the influence of bone drilling on local bone temperature and bone regeneration and determine optimal drilling speed and pressure in an animal model.

Methods: The study included 12 skeletally mature New Zealand white rabbits, weighing between 2.8 to 3.2 kg. Rabbits were divided into 2 groups and euthanized at the end of Day 21 (Group A) and Day 42 (Group B). The same drilling protocol was used in both groups. Three drill holes with different pressure (5, 10 and 20 N) were made in each rabbit tibias using 3 different rotational drill speeds (230, 370 and 570 rpm). During drilling, local temperature was recorded. Rabbit tibia underwent histopathological exam for bone regeneration.

Results: Bone temperature was affected by drilling time and depth. Lower drill speeds reduced the bone temperature and revealed better bone regeneration when compared to the drilled bones at higher drill speeds. Titanium boron nitride coating on the drill bits had no significant effects on bone temperature and structure. Bone regeneration was superior in Group B rabbits that had drilling at 230 rpm and 20 N.

Conclusion: Our results suggested that lower drilling speed with higher pressure is necessary for better bone regeneration. The optimal drilling speed is 230 rpm and optimal drilling pressure 20 N.

References

  • Augustin G, Zigman T, Davila S, Udilljak T, Staroveski T, Brezak D, et al. Cortical bone drilling and thermal osteonecrosis. Clin Biomech (Bristol, Avon) 2012;27:313-25.
  • Harder S, Egert C, Wenz HJ, Jochens A, Kern M. Influence of the drill material and method of cooling on the development of intrabony temperature during preparation of the site of an implant. Br J Oral Maxillofac Surg 2013;51:74-8.
  • Karmani S. The thermal properties of bone and the effects of surgical intervention. Curr Orthop 2006;20:52-8.
  • Reingewirtz Y, Szmukler-Moncler S, Senger B. Influence of different parameters on bone heating and drilling time in implantology. Clin Oral Implants Res 1997;8:189-97.
  • Karunakar MA, Frankenburg EP, Le TT, Hall J. The thermal effects of intramedullary reaming. J Orthop Trauma 2004;18:674-9.
  • Monfoulet L, Rabier B, Chassande O, Fricain JC. Drilled hole defects in mouse femur as models of intramembranous cortical and cancellous bone regeneration. Calcif Tissue Int 2010;86:72-81.
  • Eriksson AR, Albrektsson T. Temperature threshold levels for heat-induced bone tissue injury: a vital-microscopic study in the rabbit. J Prosthet Dent 1983;50:101-7.
  • Sugita N, Osa T, Mitsuishi M. Analysis and estimation of cutting-temperature distribution during end milling in relation to orthopedic surgery. Med Eng Phys 2009;31:101
  • Shin HC, Yoon YS. Bone temperature estimation during orthopaedic round bur milling operations. J Biomech 2006;39:33-9.
  • Augustin G, Davila S, Mihoci K, Udiljak T, Vedrina DS, Antabak A. Thermal osteonecrosis and bone drilling parameters revisited. Arch Orthop Trauma Surg 2008;128:71-7.
  • Tu YK, Tsai HH, Lin LC. Finite element simulation of drill bit and bone thermal contact during drilling. The 2nd Int. Conf., May 16-18, 2008. Bioinform Biomed Eng 2008;71:1268.
  • Aslan A, Vatansever HS, Aslan GG, Eskiizmir G, Giray G. Effect of thermal energy produced by drilling on the facial nerve: histopathologic evaluation in guinea pigs. J Laryngol Otol 2005;119:600-5.
  • Denis K, Ham GV, Sloten JV. Influence of bone milling parameters on the temperature rise, milling forces and surface flatness in view of robot assisted total knee arthroplasty. Int Congr Series 2001;1230:300-6.
  • Bachus KN, Rondina MT, Hutchinson DT. The effects of drilling force on cortical temperatures and their duration: an in vitro study. Med Eng Phys 2000;22:685-91.
  • Sharawy M, Misch CE, Weller N, Tehemar S. Heat generation during implant drilling: the significance of motor speed. J Oral Maxillofac Surg 2002;60:1160-9.
  • Abouzgia MB, James DF. Measurements of shaft speed while drilling through bone. J Oral Maxillofac Surg 1995;53:1308-16.
  • Jacob CH, Berry JT. A study of the bone machining process--drilling. J Biomech 1976:343-9.
  • Karaca F, Aksakal B, Kom M. Influence of orthopaedic drilling parameters on temperature and histopathology of bovine tibia: an in vitro study. Med Eng Phys 2011;33:1221-7.
  • Sumer M, Misir AF, Telcioglu NT, Guler AU, Yenisey M. Comparison of heat generation during implant drilling using stainless steel and ceramic drills. J Oral Maxillofac Surg 2011;69:1350-4.
There are 19 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Experimental Study
Authors

Faruk Karaca This is me

Bunyamin Aksakal This is me

Mustafa Kom This is me

Publication Date May 30, 2014
Published in Issue Year 2014

Cite

APA Karaca, F., Aksakal, B., & Kom, M. (2014). Effects of bone drilling on local temperature and bone regeneration: an in vivo study. Acta Orthopaedica Et Traumatologica Turcica, 48(3), 326-332. https://doi.org/10.3944/AOTT.2014.3074
AMA Karaca F, Aksakal B, Kom M. Effects of bone drilling on local temperature and bone regeneration: an in vivo study. Acta Orthopaedica et Traumatologica Turcica. May 2014;48(3):326-332. doi:10.3944/AOTT.2014.3074
Chicago Karaca, Faruk, Bunyamin Aksakal, and Mustafa Kom. “Effects of Bone Drilling on Local Temperature and Bone Regeneration: An in Vivo Study”. Acta Orthopaedica Et Traumatologica Turcica 48, no. 3 (May 2014): 326-32. https://doi.org/10.3944/AOTT.2014.3074.
EndNote Karaca F, Aksakal B, Kom M (May 1, 2014) Effects of bone drilling on local temperature and bone regeneration: an in vivo study. Acta Orthopaedica et Traumatologica Turcica 48 3 326–332.
IEEE F. Karaca, B. Aksakal, and M. Kom, “Effects of bone drilling on local temperature and bone regeneration: an in vivo study”, Acta Orthopaedica et Traumatologica Turcica, vol. 48, no. 3, pp. 326–332, 2014, doi: 10.3944/AOTT.2014.3074.
ISNAD Karaca, Faruk et al. “Effects of Bone Drilling on Local Temperature and Bone Regeneration: An in Vivo Study”. Acta Orthopaedica et Traumatologica Turcica 48/3 (May 2014), 326-332. https://doi.org/10.3944/AOTT.2014.3074.
JAMA Karaca F, Aksakal B, Kom M. Effects of bone drilling on local temperature and bone regeneration: an in vivo study. Acta Orthopaedica et Traumatologica Turcica. 2014;48:326–332.
MLA Karaca, Faruk et al. “Effects of Bone Drilling on Local Temperature and Bone Regeneration: An in Vivo Study”. Acta Orthopaedica Et Traumatologica Turcica, vol. 48, no. 3, 2014, pp. 326-32, doi:10.3944/AOTT.2014.3074.
Vancouver Karaca F, Aksakal B, Kom M. Effects of bone drilling on local temperature and bone regeneration: an in vivo study. Acta Orthopaedica et Traumatologica Turcica. 2014;48(3):326-32.