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Experimental investigation of the effects of levamisole in prophylaxis of fat embolism syndrome

Year 1989, Volume: 23 Issue: 1, 8 - 10, 11.09.2006

Osman Guven Tanil Esmenli

Abstract

Multipl fractures were made in rats to establish subclinical or clinical fat embolism. This expenrnental research was performed in two groups. Each group has 15 rats. Levamisole was given intraperitoneally to one group while saline solution was given to the second group. PO2, PCO2, pH and blood lipids of rats were measured 72 hours after injury, and lungs of rats were defected to define fat globules, histopatologically. Rats which were given levamisole had high blood O2 levels and low CO2 and lipid levels than the control group.

Keywords

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Yağ embolisinde Ievamizol ile profilaksi

Year 1989, Volume: 23 Issue: 1, 8 - 10, 11.09.2006

Osman Guven Tanil Esmenli

Abstract

Sıçanlarda yapılan bu deneysel calışmada 30 sıçanda multipl kırıklar oluşturuldu. Hayvanlarda oluşan klinik veya subklinik yağ embolisi araştırıldı. 15'er sıçandan oluşan 2 grup hayvandan deney grubuna kırıak sonrası intraperitoneal olarak Levamizol, kontrol gurubuna ise serum fizyolojik verildi. Her iki gruptaki hayvanlarda, 72 saat sonra arteriyel kan gazlan ve lipid miktarları tayin edildi. Her iki grubun akciğerleri. Akut respiratuar distres sendromu'' (ARDS) yönünden histopatolojik olarak incelendi. Levamizol verilen grupta, kontrol grubuna oranla daha iyi oksijenasyon olduğu laboratuar metodları ile belirlendi.

Keywords

fat embolism syndrome;prophylaxis

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Details

Primary Language English
Journal Section Experimental Study
Authors

Osman Guven This is me

Tanil Esmenli This is me

Publication Date September 11, 2006
Published in Issue Year 1989 Volume: 23 Issue: 1

Cite

APA Guven, O., & Esmenli, T. (2006). Experimental investigation of the effects of levamisole in prophylaxis of fat embolism syndrome. Acta Orthopaedica Et Traumatologica Turcica, 23(1), 8-10. https://doi.org/10.3944/aott.v23i1.1043
AMA Guven O, Esmenli T. Experimental investigation of the effects of levamisole in prophylaxis of fat embolism syndrome. Acta Orthopaedica et Traumatologica Turcica. September 2006;23(1):8-10. doi:10.3944/aott.v23i1.1043
Chicago Guven, Osman, and Tanil Esmenli. “Experimental Investigation of the Effects of Levamisole in Prophylaxis of Fat Embolism Syndrome”. Acta Orthopaedica Et Traumatologica Turcica 23, no. 1 (September 2006): 8-10. https://doi.org/10.3944/aott.v23i1.1043.
EndNote Guven O, Esmenli T (September 1, 2006) Experimental investigation of the effects of levamisole in prophylaxis of fat embolism syndrome. Acta Orthopaedica et Traumatologica Turcica 23 1 8–10.
IEEE O. Guven and T. Esmenli, “Experimental investigation of the effects of levamisole in prophylaxis of fat embolism syndrome”, Acta Orthopaedica et Traumatologica Turcica, vol. 23, no. 1, pp. 8–10, 2006, doi: 10.3944/aott.v23i1.1043.
ISNAD Guven, Osman - Esmenli, Tanil. “Experimental Investigation of the Effects of Levamisole in Prophylaxis of Fat Embolism Syndrome”. Acta Orthopaedica et Traumatologica Turcica 23/1 (September 2006), 8-10. https://doi.org/10.3944/aott.v23i1.1043.
JAMA Guven O, Esmenli T. Experimental investigation of the effects of levamisole in prophylaxis of fat embolism syndrome. Acta Orthopaedica et Traumatologica Turcica. 2006;23:8–10.
MLA Guven, Osman and Tanil Esmenli. “Experimental Investigation of the Effects of Levamisole in Prophylaxis of Fat Embolism Syndrome”. Acta Orthopaedica Et Traumatologica Turcica, vol. 23, no. 1, 2006, pp. 8-10, doi:10.3944/aott.v23i1.1043.
Vancouver Guven O, Esmenli T. Experimental investigation of the effects of levamisole in prophylaxis of fat embolism syndrome. Acta Orthopaedica et Traumatologica Turcica. 2006;23(1):8-10.