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The effects of various bone replacement materials on bone regeneration in rats

Year 1990, Volume: 24 Issue: 4, 279 - 284, 11.09.2006

Abstract

The aim of this study was to compare the effects of autogeneous and allogeneous grafts to the effects of BMP (Bone morphogenetic protein) and hydroxyapatite (pyrost), which induce osteogenesis on bone regeneration. 40 rats have been divided into five groups, each having 8 and under equivalent conditions the mentioned materials have been applied to standard calvaria defects. 4 weeks Iater osteogenesis in the defect areas has been histologically evaluated. It has been noticed that autogeneous graft was the most effective material allogeneous grafts did not have a direct integration and BMP was more efficacious than hydroxyapatite in osteogenesis induction. However it was agreed that further advanced studies are needed for applications on human beings.

Çeşitli kemik replasman materyallerinin sıçanlarda kemik rejenerasyonu üzerine etkisi (Deneysel araştırma)

Year 1990, Volume: 24 Issue: 4, 279 - 284, 11.09.2006

Abstract

Bu çalışmada otojen ve allojen greflerle, osteogenezisi uyaran BMP (Bone Morphogenetic Protein) ve hidroksiapatitin (Pyrost) kemik rejenerasyonu üzerine etkilerinin karşılaştırılması amaçlandı. 40 adet sıçanda 8’erli gruplar oluşturularak eşit şartlar altında belirtilen materyeller standart kalvaria defektlerine uygulandı. 4 hafta sonra histolojik olarak defektlerdeki osteogenez değerlendirildi. Otojen grefin en etkin materyel olduğu, allojen greflerin direkt integrasyonunun olmadığı, kemik yapımını uyarması yönünden BMP’nin hidroksiapatitten daha etkin olduğu gözlendi. Ancak insan uygulamaları için daha ileri çalışmalar gerektiği fikrine varıldı.

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Details

Primary Language English
Journal Section Experimental Study
Authors

Harzem Ozger This is me

H. Aydınok This is me

Sevgi Kullu This is me

Volkan Etus This is me

Publication Date September 11, 2006
Published in Issue Year 1990 Volume: 24 Issue: 4

Cite

APA Ozger, H., Aydınok, H., Kullu, S., Etus, V. (2006). The effects of various bone replacement materials on bone regeneration in rats. Acta Orthopaedica Et Traumatologica Turcica, 24(4), 279-284. https://doi.org/10.3944/aott.v24i4.1162
AMA Ozger H, Aydınok H, Kullu S, Etus V. The effects of various bone replacement materials on bone regeneration in rats. Acta Orthopaedica et Traumatologica Turcica. September 2006;24(4):279-284. doi:10.3944/aott.v24i4.1162
Chicago Ozger, Harzem, H. Aydınok, Sevgi Kullu, and Volkan Etus. “The Effects of Various Bone Replacement Materials on Bone Regeneration in Rats”. Acta Orthopaedica Et Traumatologica Turcica 24, no. 4 (September 2006): 279-84. https://doi.org/10.3944/aott.v24i4.1162.
EndNote Ozger H, Aydınok H, Kullu S, Etus V (September 1, 2006) The effects of various bone replacement materials on bone regeneration in rats. Acta Orthopaedica et Traumatologica Turcica 24 4 279–284.
IEEE H. Ozger, H. Aydınok, S. Kullu, and V. Etus, “The effects of various bone replacement materials on bone regeneration in rats”, Acta Orthopaedica et Traumatologica Turcica, vol. 24, no. 4, pp. 279–284, 2006, doi: 10.3944/aott.v24i4.1162.
ISNAD Ozger, Harzem et al. “The Effects of Various Bone Replacement Materials on Bone Regeneration in Rats”. Acta Orthopaedica et Traumatologica Turcica 24/4 (September 2006), 279-284. https://doi.org/10.3944/aott.v24i4.1162.
JAMA Ozger H, Aydınok H, Kullu S, Etus V. The effects of various bone replacement materials on bone regeneration in rats. Acta Orthopaedica et Traumatologica Turcica. 2006;24:279–284.
MLA Ozger, Harzem et al. “The Effects of Various Bone Replacement Materials on Bone Regeneration in Rats”. Acta Orthopaedica Et Traumatologica Turcica, vol. 24, no. 4, 2006, pp. 279-84, doi:10.3944/aott.v24i4.1162.
Vancouver Ozger H, Aydınok H, Kullu S, Etus V. The effects of various bone replacement materials on bone regeneration in rats. Acta Orthopaedica et Traumatologica Turcica. 2006;24(4):279-84.