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The effect of induced hypotension and tissue trauma on renal function in patients undergoing spinal surgery

Year 1998, Volume: 32 Issue: 1, 5 - 7, 11.09.2006

Abstract

Induced hypotensive anesthesia is the most widely used method to avoid blood loss that may even be life-threatening during spinal surgery. Surgery causes considerable trauma to bone and muscle that, along with hypotensive anesthesia, might be anticipated to impair renal function. In this study, the effect of induced hypotension on renal function in 140 patients who had spinal surgery was examined. Blood and urine tests for electrolytes, creatinine, BUN, and creatine kinase were performed both preoperatively and postoperatively, and the results were compared. An average of 280 cc of blood was replaced to compensate for an average blood loss of 300 cc. All biochemical tests gave results within normal limits. However, there was a mild hypokalemia and a mild hyponatremia in the early postoperative period which corrected in a short time. A mild decrease in ceratinine clearance (114 ml/min/1.73m2) increased to an average of 130 ml/min/1.73m2 soon after the operation. These findings show that induced hypotensive anesthesia does not impair renal function while providing the surgeon with a bloodless operative field during spinal surgery.

Omurga cerrahisi uygulanan hastalarda kontrollü hipotansiyon ve doku travmasının böbrek fonksiyonları üzerine etkisi

Year 1998, Volume: 32 Issue: 1, 5 - 7, 11.09.2006

Abstract

Kontrollü hipotansif anestezi, omurga cerrahisi sırasında meydana gelen ve hastanın hayatını tehdit ede-bilecek boyutlara varabilen kanamaların önlenmesi için yıllardır en sık başvurulan yöntemdir. Cerrahinin oluşturduğu ciddi kas ve yumuşak doku travmasının yanısıra hipotansif anestezinin de böbrek fonksiyonlarını bozabileceğine dair şüpheler vardır. Bu çalışmada kontrollü hipotansif anestezi altında omurga cerrahisi uygulanan 140 hastanın böbrek fonksiyonları değerlendirilmiştir. Preoperatif ve posroperatif kan ve idrarda elektrolit, kreatinin, BUN, ve kreatin kinaz değerleri ölçülüp karşılaştırılmıştır. Ortalama 300 cc kanama ol-duğu ve bunu kompanse etmek için 280 cc kan verildiği saptanmıştır. Tüm biyokimya değerlerinin normal sınırlarda kaldığı, postoperatif erken dönemde görülen hafif hiponatremi ve hipokaleminin ise çok kısa sürede düzeldiği belirlenmiştir. Kreatinin klirensindeki hafif düşme (114 ml/dak/1.73m2) kısa zamanda ortalama 130 ml/dak/1.73m2 değerine ulaşmıştır. Bu veriler kontrollü hipotansif anestezinin omurga cerrahisi sırasın-da kanama miktarını oldukça azaltıp kansız bir ameliyat sahası sağlayan ve böbrek fonksiyonlarını bozmadan bir yöntem olduğunu göstermiştir.

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Details

Primary Language English
Journal Section Original Article
Authors

Teoman Benli This is me

Evrim Duman This is me

Gulnur Goksan This is me

Dilek Yazicioglu This is me

Publication Date September 11, 2006
Published in Issue Year 1998 Volume: 32 Issue: 1

Cite

APA Benli, T., Duman, E., Goksan, G., Yazicioglu, D. (2006). The effect of induced hypotension and tissue trauma on renal function in patients undergoing spinal surgery. Acta Orthopaedica Et Traumatologica Turcica, 32(1), 5-7. https://doi.org/10.3944/aott.v32i1.2218
AMA Benli T, Duman E, Goksan G, Yazicioglu D. The effect of induced hypotension and tissue trauma on renal function in patients undergoing spinal surgery. Acta Orthopaedica et Traumatologica Turcica. September 2006;32(1):5-7. doi:10.3944/aott.v32i1.2218
Chicago Benli, Teoman, Evrim Duman, Gulnur Goksan, and Dilek Yazicioglu. “The Effect of Induced Hypotension and Tissue Trauma on Renal Function in Patients Undergoing Spinal Surgery”. Acta Orthopaedica Et Traumatologica Turcica 32, no. 1 (September 2006): 5-7. https://doi.org/10.3944/aott.v32i1.2218.
EndNote Benli T, Duman E, Goksan G, Yazicioglu D (September 1, 2006) The effect of induced hypotension and tissue trauma on renal function in patients undergoing spinal surgery. Acta Orthopaedica et Traumatologica Turcica 32 1 5–7.
IEEE T. Benli, E. Duman, G. Goksan, and D. Yazicioglu, “The effect of induced hypotension and tissue trauma on renal function in patients undergoing spinal surgery”, Acta Orthopaedica et Traumatologica Turcica, vol. 32, no. 1, pp. 5–7, 2006, doi: 10.3944/aott.v32i1.2218.
ISNAD Benli, Teoman et al. “The Effect of Induced Hypotension and Tissue Trauma on Renal Function in Patients Undergoing Spinal Surgery”. Acta Orthopaedica et Traumatologica Turcica 32/1 (September 2006), 5-7. https://doi.org/10.3944/aott.v32i1.2218.
JAMA Benli T, Duman E, Goksan G, Yazicioglu D. The effect of induced hypotension and tissue trauma on renal function in patients undergoing spinal surgery. Acta Orthopaedica et Traumatologica Turcica. 2006;32:5–7.
MLA Benli, Teoman et al. “The Effect of Induced Hypotension and Tissue Trauma on Renal Function in Patients Undergoing Spinal Surgery”. Acta Orthopaedica Et Traumatologica Turcica, vol. 32, no. 1, 2006, pp. 5-7, doi:10.3944/aott.v32i1.2218.
Vancouver Benli T, Duman E, Goksan G, Yazicioglu D. The effect of induced hypotension and tissue trauma on renal function in patients undergoing spinal surgery. Acta Orthopaedica et Traumatologica Turcica. 2006;32(1):5-7.