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Bacakta diyabetik yaralara bağlı nekrozitan fasiit

Year 2004, Volume: 38 Issue: 3, 195 - 199, 11.09.2006

Abstract

Amaç: Bacaktaki diyabetik yaralara bağlı gelişen nekrozitan fasiit (NF) nedeniyle tedavi edilen hastalar retrospektif olarak incelendi.
Çalışma planı: Çalışmaya bacağında diyabetik yaralara bağlı olarak NF gelişen 16 hasta (11 erkek, 5 kadın; ort. yaş 63; dağılım 50-82) alındı. Ek olarak, üç hastada koroner arter hastalığı, üç hastada ise diyabetik nefropatiye bağlı kronik böbrek yetmezliği vardı. Tüm hastalar fizik muayene, laboratuvar bulguları, direkt grafiler, kan basıncı, alınan kültür sonuçları, uygulanan tedaviler ve sonuçları açısından değerlendirildi. Hastaların hastanede kalış süresi ortalaması 26 gündü (dağılım 5-59 gün).
Sonuçlar: Dört hastada NF bacakla sınırlıyken, 10 hastada fasiit uyluğa uzanmıştı. İki olguda iki taraflı bacak tutulumu vardı. On bir hastada (%68.8) ağrı yakınması vardı. On dört hastada (%87.5) kretin kinaz değerinde artış görüldü. Direkt grafilerde yedi hastada (%43.8) yumuşak dokuda gaz görüldü. İlk cerrahi müdahale sırasında alınan kültürlerde dört hastada (%25) bir mikroorganizma, beş hastada (%31.3) ise birden fazla mikroorganizma üredi. İzole edilen 17 mikroorganizmanın 10’u (%58.8) enterobakter ailesinden idi. On bir hastaya (%68.8) dizüstü, üç hastaya (%18.8) dizaltı amputasyon yapıldı. Dört hastada ilk tedavi olarak kalça dezartikülasyonu uygulandı. İlk cerrahi girişimlerinden sonra ortalama beş kez (dağılım 2-21) debridman yapıldı. Dokuz hastada septik şok gelişti. Çoklu organ yetmezliği gelişen yedi hasta (%43.8) kaybedildi. Ölen hastalarda kreatin kinaz düzeyleri diğer hastalara göre anlamlı derecede yüksek bulundu (p<0.05).
Çıkarımlar: Diyabetik hastaların bacaklarında gelişen ve ölümcül bir enfeksiyon olan NF’de erken ve doğru tanı ve acil cerrahi tedavi hastalar için yaşam kurtarıcı olabilir.

Necrotizing fasciitis in the lower extremity secondary to diabetic wounds

Year 2004, Volume: 38 Issue: 3, 195 - 199, 11.09.2006

Abstract

Objectives: The aim of this retrospective study was to evaluate patients who developed necrotizing fasciitis (NF) in the lower extremity secondary to diabetic wounds.
Methods: The study included sixteen patients (11 men, 5 women; mean age 63 years; range 50 to 82 years) who were treated for NF arising from diabetic wounds. Associated diseases were coronary heart disease in three patients, and chronic renal failure due to diabetic nephropathy in three patients. The patients were evaluated by physical examination, direct radiographs, blood pressure measurements, and cultures, and with respect to treatment methods and results. The mean hospitalization period was 26 days (range 5 to 59 days).
Results: Necrotizing fasciitis was confined to the leg in four patients, extended to the thigh in 10 patients, and was bilateral in two patients. Pain was encountered in 10 patients (68.8%). Fourteen patients (87.5%) had increased creatine kinase levels. Direct radiographs showed gas appearance in soft tissues in seven patients (43.8%). Cultures showed a single microorganism in four patients (25%), and multiple microorganisms in five patients (31.3%). Of seventeen microorganisms isolated, 10 (58.8%) were Enterobacter species. Eleven patients (68.8%) underwent above-the-knee, and three patients (18.8%) underwent below-the-knee amputations. Disarticulation of the hip was performed in four patients. The mean number of debridements was five (range 2 to 21) following the initial surgical intervention. Nine patients developed septic shock. Seven patients (43.8%) died due to multiple organ failure. Increased creatine kinase levels were significantly associated with mortality (p<0.05).
Conclusion: Early and accurate diagnosis and prompt surgical treatment may be life-saving in diabetic patients with NF of the lower extremity

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Details

Primary Language English
Subjects Health Care Administration
Journal Section Original Article
Authors

Burak Demirag This is me

Ali Tirelioglu This is me

Bartu Sarisozen This is me

Kemal Durak This is me

Publication Date September 11, 2006
Published in Issue Year 2004 Volume: 38 Issue: 3

Cite

APA Demirag, B., Tirelioglu, A., Sarisozen, B., Durak, K. (2006). Necrotizing fasciitis in the lower extremity secondary to diabetic wounds. Acta Orthopaedica Et Traumatologica Turcica, 38(3), 195-199.
AMA Demirag B, Tirelioglu A, Sarisozen B, Durak K. Necrotizing fasciitis in the lower extremity secondary to diabetic wounds. Acta Orthopaedica et Traumatologica Turcica. September 2006;38(3):195-199.
Chicago Demirag, Burak, Ali Tirelioglu, Bartu Sarisozen, and Kemal Durak. “Necrotizing Fasciitis in the Lower Extremity Secondary to Diabetic Wounds”. Acta Orthopaedica Et Traumatologica Turcica 38, no. 3 (September 2006): 195-99.
EndNote Demirag B, Tirelioglu A, Sarisozen B, Durak K (September 1, 2006) Necrotizing fasciitis in the lower extremity secondary to diabetic wounds. Acta Orthopaedica et Traumatologica Turcica 38 3 195–199.
IEEE B. Demirag, A. Tirelioglu, B. Sarisozen, and K. Durak, “Necrotizing fasciitis in the lower extremity secondary to diabetic wounds”, Acta Orthopaedica et Traumatologica Turcica, vol. 38, no. 3, pp. 195–199, 2006.
ISNAD Demirag, Burak et al. “Necrotizing Fasciitis in the Lower Extremity Secondary to Diabetic Wounds”. Acta Orthopaedica et Traumatologica Turcica 38/3 (September 2006), 195-199.
JAMA Demirag B, Tirelioglu A, Sarisozen B, Durak K. Necrotizing fasciitis in the lower extremity secondary to diabetic wounds. Acta Orthopaedica et Traumatologica Turcica. 2006;38:195–199.
MLA Demirag, Burak et al. “Necrotizing Fasciitis in the Lower Extremity Secondary to Diabetic Wounds”. Acta Orthopaedica Et Traumatologica Turcica, vol. 38, no. 3, 2006, pp. 195-9.
Vancouver Demirag B, Tirelioglu A, Sarisozen B, Durak K. Necrotizing fasciitis in the lower extremity secondary to diabetic wounds. Acta Orthopaedica et Traumatologica Turcica. 2006;38(3):195-9.