Kemik delmenin lokal sıcaklık ve kemik rejenerasyonu üzerine etkisi: In vivo çalışma

Year 2014, Volume: 48 Issue: 3, 326 - 332, 30.05.2014

Faruk Karaca Bunyamin Aksakal Mustafa Kom

https://doi.org/10.3944/AOTT.2014.3074

Abstract

Amaç:Bu çalışmada kemik delme işleminin lokal kemik ısısı ve kemik rejenerasyonu üzerindeki etkilerinin saptanması ve optimal delme hızı ve basınç kuvvetinin bir hayvan modelinde belirlenmesi amaçlandı.

Çalışma planı: Çalışmaya iskelet gelişimini tamamlamış 12 adet Yeni Zelanda beyaz tavşanı katıldı. Tavşanların ağırlığı 2.8 ile 3.2 kg arasında değişmekteydi. Tavşanlar 2 gruba ayrılarak, 21. ve 42. gün sonunda ötenazi ile sakrifiye edildiler. Her iki grup için aynı delme protokolü kullanıldı. Tavşanların tibiasında 3 farklı basınç kuvveti (5, 10 ve 20 N) ve 3 farklı delme hızı (230, 370 ve 570 d/d) ile 3 delik açıldı. Delme sırasında oluşan bölgesel ısı kaydedildi. Daha sonra, tavşanların kemik rejenerasyonu histopatolojik çalışmalar ile incelendi.

Bulgular: Kemik ısısı delme süresi ve derinliğine bağlı değişim gösterdi. Yüksek delme hızına kıyasla düşük hızlarda kemik ısısının azaldığı ve kemik rejenerasyonun daha iyi olduğu gözlendi. Matkap uçlarındaki titanyum boron nitrit kaplamanın kemik ısısı ve yapısına etki etmediği saptandı. En iyi kemik rejenerasyonunun 230 d/d ve 20 N ile delme işleminin gerçekleştirildiği B Grubu tavşanlarda olduğu görüldü.

Çıkarımlar: Daha düşük devirde ve daha yüksek basınçla delme ile daha iyi kemik rejenerasyonu elde edilmektedir. Çalışma sonuçlarımıza göre optimal delme hızı 230 d/d ve basıncı 20 N idi.

Keywords

Delme; histopatoloji; kemik iyileşmesi; kemik rejenerasyonu.

Effects of bone drilling on local temperature and bone regeneration: an in vivo study

Abstract

Objective:The aim of this study was to examine the influence of bone drilling on local bone temperature and bone regeneration and determine optimal drilling speed and pressure in an animal model.

Methods: The study included 12 skeletally mature New Zealand white rabbits, weighing between 2.8 to 3.2 kg. Rabbits were divided into 2 groups and euthanized at the end of Day 21 (Group A) and Day 42 (Group B). The same drilling protocol was used in both groups. Three drill holes with different pressure (5, 10 and 20 N) were made in each rabbit tibias using 3 different rotational drill speeds (230, 370 and 570 rpm). During drilling, local temperature was recorded. Rabbit tibia underwent histopathological exam for bone regeneration.

Results: Bone temperature was affected by drilling time and depth. Lower drill speeds reduced the bone temperature and revealed better bone regeneration when compared to the drilled bones at higher drill speeds. Titanium boron nitride coating on the drill bits had no significant effects on bone temperature and structure. Bone regeneration was superior in Group B rabbits that had drilling at 230 rpm and 20 N.

Conclusion: Our results suggested that lower drilling speed with higher pressure is necessary for better bone regeneration. The optimal drilling speed is 230 rpm and optimal drilling pressure 20 N.

Keywords

Bone healing, bone regeneration, drilling, histopathology

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