Acute Pancreatitis Associated with Tigecycline Use: A Case Report

Abstract

Tigecycline is a broad-spectrum antibiotic used in the treatment of resistant bacterial infections. One of its rare adverse effects is acute pancreatitis. In this article, we present the case of a 48-year-old male patient with chronic liver disease due to HBV, scheduled for transplantation, who developed acute pancreatitis following tigecycline administration for cellulitis and lymphedema of the left leg.

Keywords

• Tigecycline
• Acute Pancreatitis
• Drug-Induced Pancreatitis

Supporting Institution

none

Project Number

0

Ethical Statement

As this study is a retrospective case report with anonymized data and without additional interventions, ethics committee approval was not deemed necessary.

Thanks

none

Tigesiklin Kullanımına Bağlı Akut Pankreatit: Olgu Sunumu

Abstract

Tigecycline, dirençli bakteriyel enfeksiyonların tedavisinde kullanılan geniş spektrumlu bir antibiyotiktir. Nadir görülen yan etkilerinden biri akut pankreatittir. Bu yazıda, HBV’ye bağlı kronik karaciğer hastalığı nedeniyle nakil planlanan 48 yaşında, erkek hastada sol bacağında lenfödem ve sellülit nedeniyle tigecycline kullanımına bağlı gelişen akut pankreatit olgusu sunulmuştur.

Keywords

• Tigesiklin
• akut pankreaitit
• ilaç İlişkili Pankreatit

Supporting Institution

yok

Project Number

0

Ethical Statement

Bu çalışma retrospektif bir olgu sunumudur. Hastalara ek bir işlem uygulanmamış ve tüm veriler anonimleştirilmiştir. Bu nedenle etik kurul onayı gerekmemiştir.

Thanks

yok

References

1. Hasan Arafat H, Sadaqa D, Sabateen A. Tigecycline-induced pancreatitis in a patient with recurrent malignancy: case report and literature review. Ann Med Surg (Lond). 2024.
2. Maringanti BS, Ganipisetti VM, Jun SS, Flores MI. Tigecycline Tango: A Case of Antibiotic-Induced Pancreatitis. Cureus. 2023;15(9):e44538.
3. Oxford Academic. True incidence of tigecycline-induced pancreatitis: how many cases are missed? J Antimicrob Chemother. 2021.
4. Yun Lu, Chenxuan Wang, Xiagela Maidaiti, et al. Factors linked to tigecyclineassociated acute pancreatitis: multicenter retrospective nested case-control study. iScience. 2026.