Trombositten Zengin Plazma Uygulaması Sonrası Gelişen Septik Artrit: İlk Olgu

Year 2021, Volume: 7 Issue: 3, 277 - 283, 13.10.2021

Serap Satış , Ezgi Temel Afşar Alparslan Yetişgin

Abstract

Diz osteoartriti nedeniyle trombositten zengin plazma uygulamasını takiben gelişen septik artrit olgusu, klinik ve laboratuvar bulguları eşliğinde sunuldu. 71 yaşında erkek hasta, sol dizine trombositten zengin plazma uygulaması sonrası gelişen ağrı, kısıtlılık ve şişlik şikayeti ile kliniğimize başvurdu. Fizik muayene ve laboratuvar bulguları ile septik artrit tanısı kondu. Antibiyotik ve fizik tedavi uygulamasıyla tedavi edildi. Diz osteoartriti önemli bir sağlık sorunudur. Pek çok farklı tedavi uygulanmasına rağmen, kesin tedavisi yoktur. Trombositten zengin plazma uygulaması son zamanlardaki en popüler tedavidir. Kolay uygulama, hastaneye yatmaya gerek olmaması ve yan etkilerinin düşük olması gibi avantajların yanında , antibakteriyel etkisi de vardır. Fakat diğer tüm intra artiküler uygulamalarda olduğu gibi septik artrit gibi önemli bir komplikasyonun ortaya çıkabileceği unutulmamalıdır.

Keywords

trombositten zengin plazma,, septik artrit,, komplikasyon

Supporting Institution

yok

Project Number

yok

A Case of Septic Arthritis after Platelet-Rich Plasma Administration: First Case Report

Abstract

A case of septic arthritis following platelet-rich plasma treatment due to knee osteoarthrities is presented in the context of clinical and laboratory findings. A 71 years old male patient with osteoarthrities of the knee showed pain, limitation of movement and swelling in the left knee after platelet-rich plasma administration. Septic artist is made diagnosis as a result of physical examination and medical workup. The patient was mobilized by the help of suitable antibiotic and physical therapy application. Nowadays, musculoskeletal system injuries are significant health problems. Despite the fact that many different methods have been applied for the treatment, no definitive treatment method has been determined. The platelet-rich plasma method has become increasingly popular in recent years. Platelet-rich plasma has advantages such as easy application, no need to hospitalization and low side effects, it also has an antibacterial effect. However, it should be remembered that a significant complication may occur such as septic arthritis as in all intraarticular applications.

Keywords

Platelet-Rich Plasma, Septic Arthritis, complication

Project Number

yok

References

• Arshdeep, & Kumaran, M. S. (2014). Platelet-rich plasma in dermatology: boon or a bane? Indian journal of dermatology, venereology and leprology, 80(1), 5–14. https://doi.org/10.4103/0378-6323.125467
• Azzena, B., Mazzoleni, F., Abatangelo, G., Zavan, B., & Vindigni, V. (2008). Autologous platelet-rich plasma as an adipocyte in vivo delivery system: case report. Aesthetic plastic surgery, 32(1), 155–161. https://doi.org/10.1007/s00266-007-9022-9
• Bava, E. D., & Barber, F. A. (2011). Platelet-rich plasma products in sports medicine. The Physician and sportsmedicine, 39(3), 94–99. https://doi.org/10.3810/psm.2011.09.1925
• Filardo, G., Kon, E., Buda, R., Timoncini, A., Di Martino, A., Cenacchi, A., Fornasari, P. M., Giannini, S., & Marcacci, M. (2011). Platelet-rich plasma intra-articular knee injections for the treatment of degenerative cartilage lesions and osteoarthritis. Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 19(4), 528–535. https://doi.org/10.1007/s00167-010-1238-6
• Foster, T. E., Puskas, B. L., Mandelbaum, B. R., Gerhardt, M. B., & Rodeo, S. A. (2009). Platelet-rich plasma: from basic science to clinical applications. The American journal of sports medicine, 37(11), 2259–2272. https://doi.org/10.1177/0363546509349921
• Gupta, M. N., Sturrock, R. D., & Field, M. (2001). A prospective 2-year study of 75 patients with adult-onset septic arthritis. Rheumatology (Oxford, England), 40(1), 24–30. https://doi.org/10.1093/rheumatology/40.1.24
• Kaandorp, C. J., Van Schaardenburg, D., Krijnen, P., Habbema, J. D., & van de Laar, M. A. (1995). Risk factors for septic arthritis in patients with joint disease. A prospective study. Arthritis and rheumatism, 38(12), 1819–1825. https://doi.org/10.1002/art.1780381215
• Kon, E., Buda, R., Filardo, G., Di Martino, A., Timoncini, A., Cenacchi, A., Fornasari, P. M., Giannini, S., & Marcacci, M. (2010). Platelet-rich plasma: intra-articular knee injections produced favorable results on degenerative cartilage lesions. Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 18(4), 472–479. https://doi.org/10.1007/s00167-009-0940-8
• Korucu, İsmail & Türkmen, Faik & Özer, Mustafa & Gulec, Ali & Yolcu, Bayram. (2016). Septic Artritis Development After Intra-articular Knee Injections Diz Eklem İçi Enjeksiyon Sonrası Septik Artrit Gelişimi. Selçuk Tıp Dergisi. 2016. 35-37.
• Lubkowska, Anna & Dolegowska, Barbara & Banfi, G. (2012). Growth Factor Content in PRP and their applicability in medicine.. Journal of biological regulators and homeostatic agents. 26. 3-22.
• Newman J. H. (1976). Review of septic arthritis throughout the antibiotic era. Annals of the rheumatic diseases, 35(3), 198–205. https://doi.org/10.1136/ard.35.3.198
• Rick GS, Craig JG, Mark SC. (2007) Trombosit-rich plasma: Properties and clinical applications J Lancaster Gen Hosp. 2 : 25-30.
• Sampson, S., Reed, M., Silvers, H., Meng, M., & Mandelbaum, B. (2010). Injection of platelet-rich plasma in patients with primary and secondary knee osteoarthritis: a pilot study. American journal of physical medicine & rehabilitation, 89(12), 961–969. https://doi.org/10.1097/PHM.0b013e3181fc7edf
• Wang-Saegusa, A., Cugat, R., Ares, O., Seijas, R., Cuscó, X., & Garcia-Balletbó, M. (2011). Infiltration of plasma rich in growth factors for osteoarthritis of the knee short-term effects on function and quality of life. Archives of orthopaedic and trauma surgery, 131(3), 311–317. https://doi.org/10.1007/s00402-010-1167-3
• Yılmaz B, Kesikburun S. (2013) Plateletten Zengin Plazma Uygulamaları. Turk Fiz Tip Rehab Derg. 2 : 338-44.