Maternal Tolerans

Abstract

Gebelik, babaya ait antijenler taşıyan embriyonik hücrelere karşı annenin bağışıklık sisteminin bölgesel toleransı ile karakterize fizyolojik bir durumdur. Genetik materyalinin yarısı babadan gelmesine karşın, memeliler embriyolarını uterus içerisinde taşırlar. Embriyonun uterusta yaşaması ve gelişimini sürdürebilmesi için belli bazı immunolojik mekanizmalar söz konudur. Sunulan derlemede, maternal tolerans olarak ta bilinen annenin bağışıklık sisteminin yarı yarıya kendinden olan embriyoya nasıl "tahammül" ettiği kısaca tartışılmıştır

Keywords

• Maternal tolerans

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