Protective Effect of Panax ginseng Against Carbon Tetrachloride (CCl4) - Induced Oxidative Brain Injury in Rats

Ali Karadeniz; Abdulkadir Yıldırım; Fikret Çelebi

Protective Effect of Panax ginseng Against Carbon Tetrachloride (CCl4) - Induced Oxidative Brain Injury in Rats

Year 2007, Volume: 2 Issue: 3, 0 - , 07.09.2015

Ali Karadeniz Abdulkadir Yıldırım Fikret Çelebi

Abstract

This study was designed to investigate the protective effects of Panax ginseng against acute brain damage induced by CCl4 in rats. A total of 30 healthy female Sprague–Dawley rats were divided in to three groups. Sedentary control group (group C) injected intraperitoneally (i.p.) with physiological saline as placebo for 7 consecutive days. CCl4 toxication group was injected by i.p. a single dose of CCl4 (group CCl4). Panax ginseng plus CCl4 group (200 mg/kg) was feeding through an orogastric tube for 7 consecutive days prior to CCl4 injection (group CCl4 + PG). The degree of protection in brain tissue was evaluated by the levels of malondialdehyde (MDA), glutathione (GSH), superoxide dismutase (SOD), glutathione peroxidase (GPx) and nitric oxide (NO). Panax ginseng showed a significant brain-protective effect by decreasing the level of lipid peroxidation (MDA) and elevated the activities of GSH and SOD (p<0.05). Consequently Panax ginseng was blocked oxidative brain damage induced by CCl4 in rats

Keywords

-

Year 2007, Volume: 2 Issue: 3, 0 - , 07.09.2015

Ali Karadeniz Abdulkadir Yıldırım Fikret Çelebi

Abstract

There are 0 citations in total.

Details

Primary Language	Turkish
Journal Section	Araştırma Makaleleri
Authors	Ali Karadeniz This is me Abdulkadir Yıldırım This is me Fikret Çelebi This is me
Publication Date	September 7, 2015
Published in Issue	Year 2007 Volume: 2 Issue: 3

Cite

APA	Karadeniz, A., Yıldırım, A., & Çelebi, F. (2015). Protective Effect of Panax ginseng Against Carbon Tetrachloride (CCl4) - Induced Oxidative Brain Injury in Rats. Atatürk Üniversitesi Veteriner Bilimleri Dergisi, 2(3).
AMA	Karadeniz A, Yıldırım A, Çelebi F. Protective Effect of Panax ginseng Against Carbon Tetrachloride (CCl4) - Induced Oxidative Brain Injury in Rats. Atatürk Üniversitesi Veteriner Bilimleri Dergisi. September 2015;2(3).
Chicago	Karadeniz, Ali, Abdulkadir Yıldırım, and Fikret Çelebi. “Protective Effect of Panax Ginseng Against Carbon Tetrachloride (CCl4) - Induced Oxidative Brain Injury in Rats”. Atatürk Üniversitesi Veteriner Bilimleri Dergisi 2, no. 3 (September 2015).
EndNote	Karadeniz A, Yıldırım A, Çelebi F (September 1, 2015) Protective Effect of Panax ginseng Against Carbon Tetrachloride (CCl4) - Induced Oxidative Brain Injury in Rats. Atatürk Üniversitesi Veteriner Bilimleri Dergisi 2 3
IEEE	A. Karadeniz, A. Yıldırım, and F. Çelebi, “Protective Effect of Panax ginseng Against Carbon Tetrachloride (CCl4) - Induced Oxidative Brain Injury in Rats”, Atatürk Üniversitesi Veteriner Bilimleri Dergisi, vol. 2, no. 3, 2015.
ISNAD	Karadeniz, Ali et al. “Protective Effect of Panax Ginseng Against Carbon Tetrachloride (CCl4) - Induced Oxidative Brain Injury in Rats”. Atatürk Üniversitesi Veteriner Bilimleri Dergisi 2/3 (September 2015).
JAMA	Karadeniz A, Yıldırım A, Çelebi F. Protective Effect of Panax ginseng Against Carbon Tetrachloride (CCl4) - Induced Oxidative Brain Injury in Rats. Atatürk Üniversitesi Veteriner Bilimleri Dergisi. 2015;2.
MLA	Karadeniz, Ali et al. “Protective Effect of Panax Ginseng Against Carbon Tetrachloride (CCl4) - Induced Oxidative Brain Injury in Rats”. Atatürk Üniversitesi Veteriner Bilimleri Dergisi, vol. 2, no. 3, 2015.
Vancouver	Karadeniz A, Yıldırım A, Çelebi F. Protective Effect of Panax ginseng Against Carbon Tetrachloride (CCl4) - Induced Oxidative Brain Injury in Rats. Atatürk Üniversitesi Veteriner Bilimleri Dergisi. 2015;2(3).