Fötal ve Neonatal Oksijen Taşınımı
Year 2007,
Volume: 2 Issue: 2, 50 - 57, 31.03.2010
Ali Karadeniz
İlksin Pişkin
Abstract
Plasenta membranında anne ile fetus arasındaki oksijeninin difüzyonu, pulmoner membranlardaki oksijen difüzyonuna benzer şekilde gerçekleşmektedir. Yetişkinlerde sağ ve sol atriumlar septum ile birbirinden ayrılmış olmasına rağmen, fötusta atrial septum gelişimi tamamlanmadığı için arteriel ve venöz kan birbirine karışır. Fötal dönemde dokulara oksijen taşınmasında hemoglobinin tipi ve konsantrasyonu ile
Bohr etkisi gibi faktörler önem taşımaktadır. Bu makalede, fötal ve neonatal dönemde oksijen taşınmasında etkili faktörler ile doğum öncesi ve sonrası akciğer ve dolaşım sisteminde görülen değişiklikler derlenmiştir
References
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- Battaliga, FC., Meschia, G., 1986 Introduction to Fetal Physiology. Orlando, Fla.:Academic Pres, 1986, pp-1-48.
- Bauer, C., Ludwig, I., Ludwig, M., 1968. Different effects of 2,3- diphosphoglycerate and adenosine triphosphate on the oxygen affinity haemoglobin. Life Sci. 7, 1336–1343.
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- Burchell, HB., Swan, HJC., Wood, EH., 1953. Demonstration of the differential effects on pulmonary and systemic arterial pressure by variation in oxygen content of inspired air in patent ductus arteriosus and pulmonary hypertension. Circulation.8, 681–694.
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- Carter, AM., 1975. Placental circulation. In: Comperative Placentation, edited by D. H. Steven, Academic Press, London, pp-108– 160.
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- Faber, JJ., Thornburg, KL., 1983. Placental Physiology: Structure and Function of Fetomaternal Exchange. New York: Raven Pres, pp–1–32.
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- Regulation of the
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- Makowski, EL., 1968. Maternal and fetal vascular nets in placentas of sheep and goats. Am. J. Obstet. Gynecol., 100, 283-288.
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- Rankin, JHG., Meschia, GI., Makowski, EL., Battaglia, FC., 1971. Relationship between uterine and umblical venous pO2 in sheep. Am. J. Physiol. 220, 1688–1692.
- Rasanen, J., Wood, DC., Debbs, RH., Cohen, J., Weiner, S., Huhta, JC., 1997. Reactivity of the Human Fetal Pulmonary Circulation to Maternal Hyperoxygenation Increase During the Second Half of Pregnancy. Circulation. 97; 257–262.
- Richardson, BS., Bocking AD., 1998. Metabolic and Circulatory Adaptations to Chronic Hypoxia in the Fetus. Comp. Biochem. Physiol. 119A (3) 717–723
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- Silver, M., Steven, DH., Comline, KS., 1973. Placental excahnge and morphology in ruminants and the mare. In Comline KS, Cross KW, Dawes GS et al (eds): Foetal and Neonatal Physiology.Proceedings of the Sir Joseph Barchoft Centenary Symposium. Cambridge, United Kingdom: Cambridge University Pres, pp-245-271.
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- Surgenor, D. MacN., 1974. Erythropoesis in the embryo. The Red Blood Cell. Volume I. Academic Press; pp-54–66.
- Towell, ME., 1976. Fetal respiration physiology. In: Goodwin, JW; Godden JO; Chance GW (eds). Longman Canada Ltd., pp-171-186. Toronto,
- West, B., 1980. Physiology of Pregnancy. Best and Taylor’s Physiological basis and medical practice.11.Edition; pp-892–909.
- Yılmaz, B., 2000. Dölütte kan dolaşımı (Fötal dolaşım). Fizyoloji, 2. baskı. Feryal matbaacılık; S-324
- Young, M., 1963. The Fetal and Neonatal Handbook Circulation. .Section II. Circulation. Volume II. Hmilton W. F. and Dow P. (Edit). American Physiological Society; pp-1619–1645. Young, M., Preston, M.A., 1981. The Interrelations of Maternal-Fetal Transfer and Placental Blood Flow. Placental Transfer: Methods and Interpretations.W. B. Saunders Company Ltd.; pp-45-64.
Year 2007,
Volume: 2 Issue: 2, 50 - 57, 31.03.2010
Ali Karadeniz
İlksin Pişkin
References
- Bartels, H., Moll, W., Metcalfe, J., 1962. Physiology of gas exchange in the human placenta. Am. J. Obstet. Gynecol. 84, 1714– 1730.
- Battaliga, FC., Meschia, G., 1986 Introduction to Fetal Physiology. Orlando, Fla.:Academic Pres, 1986, pp-1-48.
- Bauer, C., Ludwig, I., Ludwig, M., 1968. Different effects of 2,3- diphosphoglycerate and adenosine triphosphate on the oxygen affinity haemoglobin. Life Sci. 7, 1336–1343.
- Brittan, T., 2002. Molecular aspects of embryonic hemoglobin function. Molecular Aspects of Medicine, 23; 293–342.
- Burchell, HB., Swan, HJC., Wood, EH., 1953. Demonstration of the differential effects on pulmonary and systemic arterial pressure by variation in oxygen content of inspired air in patent ductus arteriosus and pulmonary hypertension. Circulation.8, 681–694.
- Burton, GJ., Jaunaix, E., 2001. Maternal vascularisation and of the human placenta: does the embryo develop in a hypoxic environment? Gynecol Obstet Fertil. 29; 503–508.
- Carter, AM., 1975. Placental circulation. In: Comperative Placentation, edited by D. H. Steven, Academic Press, London, pp-108– 160.
- Cunningham, JG., 2002. Fetal and neonatal oxygen transport. Textbook of veterinary physiology. 3 rd edit. W. B. Saunders Company;pp-516–522.
- Dawes, GS., 1968. Foetal and Neonatal Physiology. A comparative study of the changes at birth. Chicago: Year Book Medical.pp-164-170
- Faber, JJ., Thornburg, KL., 1983. Placental Physiology: Structure and Function of Fetomaternal Exchange. New York: Raven Pres, pp–1–32.
- Giacomo, M., 1989. Placental Respiratory gas exchange and fetal oxygenation. Maternal and Fetal Medicine: Principles and Practice; Robert K Creasy and Robert Resnik.(edit) W. B. Saunders Company; 2 th Edit.; pp- 303–313
- Guyton, AC., Hall, JE., 1996. Fetal ve Neonatal Fizyoloji. Tıbbi Fizyoloji. Textbook of Medical Physiology, 9. Edit.; pp-425–433
- Hassa, O., Aştı, R., 1997. Plasentanın oluşması. Embriyoloji. 3. baskı, S-77–93. Haymen, MA.,
- Regulation of the
- pulmonary circulation in the perinatal period and in children. Intens. Care. Med. 15, S9- 12.
- Haymann, MA., 1986. Fetal and neonatal circulation. Prenatal and Perinatal Biology and Medicine.Volume I. Physiology and Growth. Norman Kretchmer, Edward J Qulligan and John D. Johnson (Edits) Harword Academic Publishers; pp-227–259.
- Leff, AR., Schumacker, PT., 1993. Respiratory Physiology: Philedelphia: WB Saunders, pp-137–154.
- Makowski, EL., 1968. Maternal and fetal vascular nets in placentas of sheep and goats. Am. J. Obstet. Gynecol., 100, 283-288.
- Morris, FK., 1988. Placental Transport. The Physiology of Reproduction. E. Knobil and J. Neil et al. (Edit) Raven Press, Ltd., New York; pp-2043-2082
- Murray, JF:, 1976. The Normal Lung: The Basis for Diagnosis and Treatment of Pulmonary Disease, 2nd ed. Philedelpia: WB Saunders, pp-1–21.
- Noyan, A., 1998. Fötüs ve Plasenta Kan Dolaşımı. Yaşamda ve Hekimlikte Fizyoloji. 10. baskı. Meteksan, Ankara. 846–850.
- Rankin, JHG., Meschia, GI., Makowski, EL., Battaglia, FC., 1971. Relationship between uterine and umblical venous pO2 in sheep. Am. J. Physiol. 220, 1688–1692.
- Rasanen, J., Wood, DC., Debbs, RH., Cohen, J., Weiner, S., Huhta, JC., 1997. Reactivity of the Human Fetal Pulmonary Circulation to Maternal Hyperoxygenation Increase During the Second Half of Pregnancy. Circulation. 97; 257–262.
- Richardson, BS., Bocking AD., 1998. Metabolic and Circulatory Adaptations to Chronic Hypoxia in the Fetus. Comp. Biochem. Physiol. 119A (3) 717–723
- Rurak, DW., Richardson BS., Patrick JE., Carnichael L., Homan J 1990. Blood flow and oxygen delivery to fetal organs and tissues during sutained hypoxemia. Am. J. Physiol. 258, R1116-1122.
- Saling, E., 1969. Foetal and Neonatal Hypoxia in relation to clinical obstetric practice; Baltimore: Willimas and Wilkins.pp-1–11
- Sheldon, RE., Peeters, LLH., Jones, MD., Makowski, Redistribution of cardiac output and oxygen delivery in the hypoxemic fetal lamb. Am. J. Obstet. Gynecol. 135, 1071–1078. 1979.
- Silver, M., Steven, DH., Comline, KS., 1973. Placental excahnge and morphology in ruminants and the mare. In Comline KS, Cross KW, Dawes GS et al (eds): Foetal and Neonatal Physiology.Proceedings of the Sir Joseph Barchoft Centenary Symposium. Cambridge, United Kingdom: Cambridge University Pres, pp-245-271.
- Stevenson, RE., 1973. Oxygen. The Fetus Newly Born Infant. The C. V. Mosby Company;pp-326–350.
- Surgenor, D. MacN., 1974. Erythropoesis in the embryo. The Red Blood Cell. Volume I. Academic Press; pp-54–66.
- Towell, ME., 1976. Fetal respiration physiology. In: Goodwin, JW; Godden JO; Chance GW (eds). Longman Canada Ltd., pp-171-186. Toronto,
- West, B., 1980. Physiology of Pregnancy. Best and Taylor’s Physiological basis and medical practice.11.Edition; pp-892–909.
- Yılmaz, B., 2000. Dölütte kan dolaşımı (Fötal dolaşım). Fizyoloji, 2. baskı. Feryal matbaacılık; S-324
- Young, M., 1963. The Fetal and Neonatal Handbook Circulation. .Section II. Circulation. Volume II. Hmilton W. F. and Dow P. (Edit). American Physiological Society; pp-1619–1645. Young, M., Preston, M.A., 1981. The Interrelations of Maternal-Fetal Transfer and Placental Blood Flow. Placental Transfer: Methods and Interpretations.W. B. Saunders Company Ltd.; pp-45-64.