Şanlıurfa’da Ambalajsız Olarak Tüketime Sunulan Sütlerde Beta-Lactam Kalıntılarının Araştırılması
Year 2006,
Volume: 1 Issue: 4, 74 - 77, 18.04.2010
Mustafa Ardıç
Hisamettin Durmaz
Abstract
Bu çalışmada Şanlıurfa bölgesinde tüketilen süt örneklerinde beta-laktam kalıntılarının kalitatif
olarak belirlenmesi amaçlandı. Süt örnekleri yaz ve kış aylarında toplandı. Araştırmada antibiyotiklere
duyarlı mikroorganizma olan Bacillus stearothermophilus kullanıldı. 300 süt örneğinin 96’sı inhibitör madde
bakımından pozitif olarak belirlendi. Pozitif numunelerden 64’ünün beta-laktam antibiyotik kalıntısı, 32’sinin
antimikrobiyel aktiviteye sahip diğer kalıntıları içerdiği belirlendi. Araştırma, Şanlıurfa yöresinde tüketime
sunulan sütlerin önemli bir kısmının antibiyotik kalıntısı içerdiğini göstermiştir.
References
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- Seymour, EH., Jones, GM., McGilliard, ML., (1988). Persistence of residues in milk following antibiotic treatment of dairy cattle. J. Dairy Sci. 71, 2292-2296.
- Srikandakumar, A., Johnson, EH., Nsanzi, H., Al-Abri, KS., (2004). Microbes and anti- microbial substances in pasteurized milk sold in Oman. Int. J. Food Prop. 7, 615-627.
- Sternesjö, A., Johnson, G., (1998). A novel rapid enzyme immunoassay (Fluorophos BetaScreen) for detection of ß-lactam residues in ex-farm raw milk. J. Food Prot. 61 (7), 808-811.
- Sternesjö, A., Johnson, G., (2003). The Swedish system for detection and separation of ßlactam antibiotics contaminated milk-a practical approach. Milchwissenschaft 58 (1/2), 68-69.
- Sudershan, V., Bhat, R., (1995). A survey on veterinary drug use and residues in milk in Hyderabad. Food Addit. Contam. 12 (5), 645-650.
- Suhren, G., Hoffmeister, A., Reichmut, J., Heeschen, W., (1990). Incidence of inhibitory substances in milk for consumption from various European countries. Milchwissenschaft 45 (8), 485- 490.
- Temiz, A., Öner, Z., (1988). Ankara’daki iki ayrı süt işletmesine gelen çiğ sütlerde antibiyotik varlığının belirlenmesi. Gıda 13 (4), 289-295.
- Yamani, MI., Al-Kurdi, LMA., Haddadin, MSY., Robinson, RK., (1999). A simple test for the detection of antibiotics and other chemical residues in ex-farm milk. Food Control 10, 35-39.
Year 2006,
Volume: 1 Issue: 4, 74 - 77, 18.04.2010
Mustafa Ardıç
Hisamettin Durmaz
References
- AOAC (2000). Official Methods of Analysis. 17th ed., Association of Official Agricultural Chemist, Maryland.
- Borges, GT., Santana, AP., Mesquita, AJ., Mesquita, SQP., Silva, LAF., Nunes, VQ., (2000). Residues of antibiotics in integral and standard pasteurized milk produced and commercialized in Goiás, Brazil. Cienc. Anim. Bras. 1, 59-63.
- Cinquina, AL., Roberti, P., Giannetti, L., Longo, F., Draisci, R, Fagiolo, A., Brizioli, NR., (2003). Determination of enrofloxacin and its metabolite ciprofloxacin in goat milk by high-performance liquid chromatography with diode-array detection optimization and validation. J. Chromatogr. A 987, 221-226.
- Dokuzlu, C., Tayar, M., (2001). Bursa ve çevresinde çiğ sütlerde antibiyotik varlığının belirlenmesi. Vet. Bil. Derg. 17 (1), 153-157.
- Folly, M., Machado, S., (2001). Antibiotic residues determination, using microbial inhibition, protein binding and immunoassays methods, in pasteurized milk commercialized in the northern region of Rio de Janeiro State, Brazil. Cienc. Rural 31 (1), 95-98.
- Gardner, IA., Hird, DW., Utterback, WW., Danaye-Elmi, C., Heron, BR., Christiansen, KH., Sischo, WM., (1990). Mortality, morbidity, case-fatality, and culling rates for California dairy cattle as evaluated by the National Animal Health Monitoring System, 1986-1987. Prev. Vet. Med. 8, 157.
- Gaudin, V., Fontaine, J., Maris, P., (2001). Screening of penicillin residues in milk by surface plasmon resonance-based biosensor assay: comparison of chemical and enzymatic sample pre-treatment. Anal. Chim. Acta. 436, 191-198.
- Guterbock, W.M., (1995). Rational treatment of clinical mastitis. In: Proceedings of the 2nd Western Large Herd Dairy Management Conference, Las Vagas, Nevada, USA 49- 59.
- Jones, GM., Seymour, EH., (1988). Cowside antibiotic residue testing. J. Dairy Sci. 71, 1691-1699.
- Kang'ethe, EK., Aboge, GO., Arimi, SM., Kanja, LW., Omore, O., McDermott, JJ., (2005). Investigation of the risk of consuming marketed milk with antimicrobial residues in Kenya. Food Control 16, 349-355.
- Koç, Ş., Akyüz, N. (2001). Çiğ sütlerde antibiyotik varlığının belirlenmesi üzerine bir araştırma. In: GAP II. Tarım Kongresi 24-26 Ekim. Şanlıurfa, Türkiye. 507-512.
- McGrane, P., Rowe, MT., Anger, S., (1996). Evaluation of delvotest SP and Charm AIM-96 for the detection a range of antibiotics in milk. Milchwissenschaft 51, 330-333.
- Meek, AH., Martin, SW., Stone, JB., McMillan, I., Britney, JB. Grieve, DG. (1986). The relationship among current management systems, production, disease and drug usage on Ontario dairy farms. Can. J. Vet. Res. 50, 7.
- Molina, MP., Althaus, RL., Balasch, S., Torres, A., Peris, C. Fernandez, N., (2003). Evaluation of screening test for detection of antimicrobial residues in ewe milk. J. Dairy Sci. 86, 1947-1952.
- Nascimento, GGF., Maestro, V., Campos, MSP., (2001). The occurrence of antibiotic residues in milk in commercial establishments in the city of Piracicaba, Sao Paulo, Brazil. Rev. Nutr. 14 (2), 119-124.
- Olcay, ME., Eldem, H. (1990) Gıda Maddeleri Tüzüğü. Bayrak Matbaacılık, İstanbul
- Önal, A., Aydın, N., Ayaz, Y., İşcan, D., Savaş, N., (1993). Süt ve etlerde bulunan bazı antibiyotiklerin çeşitli yöntemlerle saptanması. Etlik Vet. Mik. Enst. Derg. 7, 34-51.
- Ramirez, A., Gutierrez, R., Diaz, G., Gonzalez, C., Perez, N., Salvador, V., Noa, M., (2003). High-performance thin-layer chromatography-bioautography for multiple antibiotic residues in cow’s milk. J. Chromatogr. B 784, 315-322.
- Reneau, JK., (1993). Clinical mastitis records in production medicine programs. Comp. Cont. Ed. Pract. Vet. 15, 497-503.
- Resmi Gazete 2002. Türk Gıda Kodeksi Hayvansal Kökenli Gıdalarda Veteriner İlaçları Maksimum Kalıntı Limitleri Tebliği. Tebliğ No. 2002/30. Resmi Gazete Sayı 24739, Başbakanlık Mevzuatı Geliştirme ve Yayın Genel Müdürlüğü, Ankara.
- Rybinska, K., Postupolski, J., Szczesna, M., (1995). Residues of antibiotics and other inhibitory substances in milk. Rocz. Panstw. Zakl. Hig. 46 (3), 239-241.
- Schenck, FJ., Callery, PS., (1998). Chromatographic methods of analysis of antibiotics in milk. J. Chromatogr. A 812, 99-109.
- Seymour, EH., Jones, GM., McGilliard, ML., (1988). Persistence of residues in milk following antibiotic treatment of dairy cattle. J. Dairy Sci. 71, 2292-2296.
- Srikandakumar, A., Johnson, EH., Nsanzi, H., Al-Abri, KS., (2004). Microbes and anti- microbial substances in pasteurized milk sold in Oman. Int. J. Food Prop. 7, 615-627.
- Sternesjö, A., Johnson, G., (1998). A novel rapid enzyme immunoassay (Fluorophos BetaScreen) for detection of ß-lactam residues in ex-farm raw milk. J. Food Prot. 61 (7), 808-811.
- Sternesjö, A., Johnson, G., (2003). The Swedish system for detection and separation of ßlactam antibiotics contaminated milk-a practical approach. Milchwissenschaft 58 (1/2), 68-69.
- Sudershan, V., Bhat, R., (1995). A survey on veterinary drug use and residues in milk in Hyderabad. Food Addit. Contam. 12 (5), 645-650.
- Suhren, G., Hoffmeister, A., Reichmut, J., Heeschen, W., (1990). Incidence of inhibitory substances in milk for consumption from various European countries. Milchwissenschaft 45 (8), 485- 490.
- Temiz, A., Öner, Z., (1988). Ankara’daki iki ayrı süt işletmesine gelen çiğ sütlerde antibiyotik varlığının belirlenmesi. Gıda 13 (4), 289-295.
- Yamani, MI., Al-Kurdi, LMA., Haddadin, MSY., Robinson, RK., (1999). A simple test for the detection of antibiotics and other chemical residues in ex-farm milk. Food Control 10, 35-39.