Venlafaksin Sonrası Gelişen Uygunsuz Antidiüretik Hormon Salınımı Sendromu : Vaka Sunumu
Year 2024,
Volume: 7 Issue: 3, 141 - 144, 15.11.2024
Mert Bektaş
,
Mehmet Sami İslamoğlu
,
Serap Yavuzer
,
Mahir Cengiz
Abstract
Hiponatremi serum sodyum konsantrasyonunun normalin altında olması olup klinik pratikte oldukça sık karşılaşılan bir durumdur. Hiponatremi ile başvuran hastaların acil tedavisi başlandıktan sonra etiyolojik incelemesinin mutlaka yapılması gerekmektedir. Övolemik hiponatremi ile başvuran hastalarda ise uygunsuz antidiüretik hormon salınımı sendromu (UADHS) mutlaka akla getirilmelidir. Venlafaksin gibi sıkça kullanılan bazı ilaçlar UADHS’a sebep olabilmektedir. Bu yazımızda, nöropatik ağrı sebebiyle venlafaksin başlanan bir hastada gelişen UADHS vakası sunulmuştur.
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Year 2024,
Volume: 7 Issue: 3, 141 - 144, 15.11.2024
Mert Bektaş
,
Mehmet Sami İslamoğlu
,
Serap Yavuzer
,
Mahir Cengiz
References
- Poch E, Molina A, Piñeiro G. Syndrome
of inappropriate antidiuretic hormone secretion.
Med Clin (Barc). 2022;159(3):139-
146. doi:10.1016/j.medcli.2022.02.015
- Meyer I, Frank D, Janssens U. [A case of
venlafaxine-induced syndrome of inappropriate
ADH secretion (SIADH) - treatment
with tolvaptan]. Dtsch Med Wochenschr.
2012;137(21):1096-1099. doi:
10.1055/s-0032-1305012
- Thompson C, Hoorn EJ. Hyponatraemia:
an overview of frequency, clinical presentation
and complications. Best Pract Res Clin
Endocrinol Metab. 2012;26 Suppl 1:S1-6.
doi:10.1016/S1521-690X(12)00019-X
- Peri A, Grohé C, Berardi R, Runkle I.
SIADH: differential diagnosis and clinical
management. Endocrine. 2017;55(1):311-
319. doi:10.1007/s12020-016-0936-3
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of inappropriate antidiuretic hormone:
prevalence, causes and consequences*.
European Journal of Endocrinology.
2010;162(Supplement_1):S5-S12.
doi:10.1530/EJE-09-1063
- Shepshelovich D, Schechter A, Calvarysky
B, Diker-Cohen T, Rozen-Zvi B, Gafter-
Gvili A. Medication-induced SIADH:
distribution and characterization according
to medication class. Br J Clin Pharmacol.
2017;83(8):1801-1807. doi:10.1111/
bcp.13256
- Jones DP. Syndrome of Inappropriate
Secretion of Antidiuretic Hormone and
Hyponatremia. Pediatrics In Review.
2018;39(1):27-35. doi:10.1542/pir.2016-
0165
- Sato A, Yasui-Furukori N, Oda Y, et al.
Asymptomatic syndrome of inappropriate
secretion of antidiuretic hormone
(SIADH) following duloxetine treatment
for pain with depression: Two case reports.
Neuropsychopharmacology Reports.
2022;42(3):387-390. doi:10.1002/
npr2.12279
- Smith JM. Clinical implications of treating
depressed older adults with SSRIs:
possible risk of hyponatremia. J Gerontol
Nurs. 2010;36(4):22-27; quiz 28-29.
doi:10.3928/00989134-20100202-04
- Gandhi S, Shariff SZ, Al-Jaishi A, Reiss
JP, Mamdani MM, Hackam DG, et al. Second-
generation antidepressants and hyponatremia
risk: a population-based cohort
study of older adults. Am J Kidney Dis.
2017;69:87–96
- Letmaier M, Painold A, Holl AK, Vergin
H, Engel R, Konstantinidis A, et al. Hyponatraemia
during psychopharmacological
treatment: results of a drug surveillance
programme. Int J Neuropsychopharmacol.
2012;15:739–48