Nadir ve Özel Bir Komplikasyon: Over Hiperstimülasyon Sendromuna Bağlı Plevral Efüzyon

Year 2025, Volume: 8 Issue: 3, 249 - 254, 18.11.2025

Suzan Temiz Bekce

Abstract

Ovarian Hiperstimülasyon Sendromu (OHSS); iatrojenik olabildiği gibi overlerin uyarılması için verilen tedaviye karşı aşırı bir yanıt ve hassasiyet olarak tanımlanmaktadır. Çok farklı klinik ve laboratuvar bulgularıyla görülebilmektedir. Overlerin stimülasyonun bir sonucu olarak, serum intravasküler alandan üçüncü boşluğa geçiş yaparak; assit ve plevral efüzyon gibi komplikasyonlara yol açabilir.

Bu yazıda ovulasyon indüksiyonu tedavisi uygulanan, ve takiplerinde plevral mayi tespit edilen iki olgu literatür eşliğinde sunuldu. Assite parasentez ile yapılan müdahale sonrasında plevral mayini geriledği , hastanın kliniğinin düzeldiği görülmüştür.

Yardımcı üreme tekniklerinin gün geçtikçe daha yaygın kullanımıyla OHSS daha sık görülebilir. Bu sebeple Plevral efüzyonun nadir nedenlerinden biri olan OHSS’yi olgular eşliğinde tartışmayı, uygun tedavi ve takip stratejilerin ilk aşamada belirlenmesinin önemini hatırlatmak istedik.

Keywords

assit , over hiperstimülasyon sendromu , plevral efüzyon

A Rare and Unique Complication: Pleural Effusıon Associated With Ovarian Hyperstimulation Syndrome

Abstract

Ovarian Hyperstimulation Syndrome (OHSS) is defined as an excessive response and hypersensitivity to the treatment administered to stimulate the ovaries, which can also occur iatrogenically. It can present a wide range of clinical and laboratory findings. As a result of ovarian stimulation, serum fluid can shift from the intravascular compartment to the third space, leading to complications such as ascites and pleural effusion.
This article presents two cases of patients who underwent ovulation induction therapy and were found to have pleural effusion during follow-up, along with a review of the literature. Following an intervention with paracentesis to manage ascites, regression of the pleural effusion and improvement in the patients' clinical condition were observed.
With the increasing use of assisted reproductive techniques, OHSS may be encountered more frequently. Therefore, we aim to discuss OHSS, a rare cause of pleural effusion, through these cases and emphasize the importance of determining appropriate treatment and follow-up strategies at the initial stage.

Keywords

ascites , ovarian hyperstimulation syndrome , pleural effusion

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