INVESTIGATION OF RADIOSENSITIVITY OF GAMMA IRRADIATED ISONIAZID ANTIBIOTIC THROUGH EPR SPECTROSCOPY
Abstract
Dosimetric properties of gamma irradiated Isoniazid (IS) were investigated through Electron Paramagnetic Resonance (EPR) spectroscopy. While unirradiated IS presented no EPR signal, irradiated IS exhibited a significant EPR spectrum at room temperature. Some EPR parameters of obtained experimental spectrum were calculated. In order to describe the variation of EPR signal intensity with absorbed radiaiton dose, several mathematical equations were tried. It has been determined that the best fit of IS sample is with polinomial function (R2 = 0.9675). Moreover time dependency of the intensity of the EPR signal of the irradiated sample was analysed to study the stability of the free radicals.
Keywords
References
- Coşkun M, Coşkun M. Biological dosimeter and related developments. Cerrahpaşa J Med 2003; 34: 207-218.
Details
Primary Language
English
Subjects
Engineering
Journal Section
Research Article
Authors
Kerem Sütçü
DİCLE ÜNİVERSİTESİ
Türkiye
Yunus Emre Osmanoğlu
This is me
DİCLE ÜNİVERSİTESİ
Türkiye
Fırat Akbalık
DİCLE ÜNİVERSİTESİ
Türkiye
Publication Date
December 1, 2016
Submission Date
November 16, 2016
Acceptance Date
November 22, 2016
Published in Issue
Year 2016 Volume: 17 Number: 4
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