NEW THIOPHENE BEARING DIMETHYL-5-HYDROXY ISOPHTALATE ESTERS AND THEIR ANTIMICROBIAL ACTIVITIES

Hakan Ünver; Zerrin Canturk

doi:10.18038/aubtda.335519

EN

NEW THIOPHENE BEARING DIMETHYL-5-HYDROXY ISOPHTALATE ESTERS AND THEIR ANTIMICROBIAL ACTIVITIES

Abstract

Thiophene belongs to a class of heterocyclic compounds. In this study, three new dimethyl-5-hydroxy isophtalate derived thiophene esters were successfully synthesized and characterized by FT-IR, elemental analysis, ¹H-NMR, ¹³C-NMR and HR-Mass techniques. Synthesized compounds antimicrobial effects were tested on Staphylococcus aureus (ATCC 25923); Enterococcus faecalis (ATCC 29212); Enterococcus faecalis (ATCC 51922); Klebsiella pneumoniae (ATCC 700603); Pseudomonas aeruginosa (ATCC 27853); Escherichia coli (ATCC 35218); Escherichia coli (ATCC 25922) and Candida albicans (ATCC 90028); Candida glabrata (ATCC 90030); Candida krusei (ATCC 6258); Candida parapsilosis (ATCC 22019). Compound C₁ showed the highest antimicrobial activity, possessing the same potential as chloramphenicol against, P. aeruginosa ATCC 27853. According to MTT assays, this compound was identified as non-toxic.

Keywords

Thiophene,Antibacterial,Anticandidal,MIC,Ketokanazole

References

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Details

Primary Language

English

Subjects

Engineering

Journal Section

Research Article

Authors

Hakan Ünver
ANADOLU ÜNİVERSİTESİ
Türkiye

Zerrin Canturk
ANADOLU ÜNİVERSİTESİ
Türkiye

Publication Date

March 31, 2018

Submission Date

August 21, 2017

Acceptance Date

November 21, 2017

Published in Issue

Year 2018 Volume: 19 Number: 1

DOI

https://doi.org/10.18038/aubtda.335519

IZ

https://izlik.org/JA52DG24MD

APA

Ünver, H., & Canturk, Z. (2018). NEW THIOPHENE BEARING DIMETHYL-5-HYDROXY ISOPHTALATE ESTERS AND THEIR ANTIMICROBIAL ACTIVITIES. Anadolu University Journal of Science and Technology A - Applied Sciences and Engineering, 19(1), 43-49. https://doi.org/10.18038/aubtda.335519

AMA

1.Ünver H, Canturk Z. NEW THIOPHENE BEARING DIMETHYL-5-HYDROXY ISOPHTALATE ESTERS AND THEIR ANTIMICROBIAL ACTIVITIES. AUJST-A. 2018;19(1):43-49. doi:10.18038/aubtda.335519

Chicago

Ünver, Hakan, and Zerrin Canturk. 2018. “NEW THIOPHENE BEARING DIMETHYL-5-HYDROXY ISOPHTALATE ESTERS AND THEIR ANTIMICROBIAL ACTIVITIES”. Anadolu University Journal of Science and Technology A - Applied Sciences and Engineering 19 (1): 43-49. https://doi.org/10.18038/aubtda.335519.

EndNote

Ünver H, Canturk Z (March 1, 2018) NEW THIOPHENE BEARING DIMETHYL-5-HYDROXY ISOPHTALATE ESTERS AND THEIR ANTIMICROBIAL ACTIVITIES. Anadolu University Journal of Science and Technology A - Applied Sciences and Engineering 19 1 43–49.

IEEE

[1]H. Ünver and Z. Canturk, “NEW THIOPHENE BEARING DIMETHYL-5-HYDROXY ISOPHTALATE ESTERS AND THEIR ANTIMICROBIAL ACTIVITIES”, AUJST-A, vol. 19, no. 1, pp. 43–49, Mar. 2018, doi: 10.18038/aubtda.335519.

ISNAD

Ünver, Hakan - Canturk, Zerrin. “NEW THIOPHENE BEARING DIMETHYL-5-HYDROXY ISOPHTALATE ESTERS AND THEIR ANTIMICROBIAL ACTIVITIES”. Anadolu University Journal of Science and Technology A - Applied Sciences and Engineering 19/1 (March 1, 2018): 43-49. https://doi.org/10.18038/aubtda.335519.

JAMA

1.Ünver H, Canturk Z. NEW THIOPHENE BEARING DIMETHYL-5-HYDROXY ISOPHTALATE ESTERS AND THEIR ANTIMICROBIAL ACTIVITIES. AUJST-A. 2018;19:43–49.

MLA

Ünver, Hakan, and Zerrin Canturk. “NEW THIOPHENE BEARING DIMETHYL-5-HYDROXY ISOPHTALATE ESTERS AND THEIR ANTIMICROBIAL ACTIVITIES”. Anadolu University Journal of Science and Technology A - Applied Sciences and Engineering, vol. 19, no. 1, Mar. 2018, pp. 43-49, doi:10.18038/aubtda.335519.

Vancouver

1.Hakan Ünver, Zerrin Canturk. NEW THIOPHENE BEARING DIMETHYL-5-HYDROXY ISOPHTALATE ESTERS AND THEIR ANTIMICROBIAL ACTIVITIES. AUJST-A. 2018 Mar. 1;19(1):43-9. doi:10.18038/aubtda.335519

NEW THIOPHENE BEARING DIMETHYL-5-HYDROXY ISOPHTALATE ESTERS AND THEIR ANTIMICROBIAL ACTIVITIES

Abstract

Keywords

Abstract

References

Details

Primary Language

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Authors

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Acceptance Date

Published in Issue

DOI

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