Malignancy Associated Aortitis in a Patient with Fever of Unknown Origin
Abstract
Aortitis, characterized by inflammatory changes in the aortic wall, can present with various manifestations. It should be considered in the differential
diagnosis of fever of unknown origin (FUO), especially in patients with aortic aneurysm. Accurate differentiation between infectious and noninfectious
aortitis is essential for appropriate treatment. Clinicians must also remain vigilant regarding the potential malignancy risk in patients
with vasculitis during initial evaluation and follow-up. This study presents a case of malignancy-associated large vessel vasculitis identified in a
patient with FUO.
Keywords
Aortitis, large vessel vasculitis, fever of unknown origin
Ethical Statement
Written informed consent was obtained from the patient for publication of this case report and accompanying images.
References
- 1. Yuan SM, Lin H. Aortitis presenting as fever of unknown origin. Ann Thorac Cardiovasc Surg. 2018;24:279-287.
- 2. Hankard A, Puéchal X, Martin Silva N, et al. Characteristics of ANCAassociated vasculitis with aneurysms: case series and review of the literature. Autoimmun Rev. 2023;22:103293.
- 3. Tyagi S, Safal S, Tyagi D. Aortitis and aortic aneurysm in systemic vasculitis. Indian J Thorac Cardiovasc Surg. 2019;35(Suppl 2):47-56.
- 4. Saadoun D, Vautier M, Cacoub P. Medium- and large-vessel vasculitis. circulation. 2021;143:267-282.
- 5. Kermani TA, Warrington KJ, Amin S. Malignancy risk in vasculitis. Ther Adv Musculoskelet Dis. 2011;3:55-63.
- 6. Sharma S, Pandey NN, Sinha M, et al. Correction to: etiology, diagnosis and management of aortitis. Cardiovasc Intervent Radiol. 2020;43:1837-1838.
- 7. Gornik HL, Creager MA. Aortitis. Circulation. 2008;117:3039-3051.
- 8. Carrer M, Vignals C, Berard X, et al. Retrospective multicenter study comparing ınfectious and noninfectious aortitis. Clin Infect Dis. 2023;76:e1369-e1378.