Research Article
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IS DOPPLER TISSUE EARLY LEFT VENTRICULAR FILLING VELOCITY PRELOAD INDEPENDENT OF PRELOAD ALTERING MANEUVERS?

Year 2001, Volume: 54 Issue: 3, 205 - 210, 30.09.2001
https://izlik.org/JA79XF88HL

Abstract

Objective. Transmitral Doppler flow indices are used to evaluate diastolic /uncfion. Recently, Dofiipler tissue velocities have been used as an index of lefi ventricular relaxation. The aim of this study was to determine whether Doppler tissue velocities are influenced by |ore- load alterations.

Methods. We altered lefi ventricular |oreIoads in I7 patients (all men, 49z8 years) while recording echocar- diogra|ohic measurements of left ventricular end-diastolic volume, leff atrial maxima/ area, |oeak early Doppler fill- ing velocity and lefi ventricular myocardial velocities during early filling. Preload altering maneuvers included Trendelenburg (Stage 1), reverse Trendelenburg (Stage 2) and amyl nitrate (Stage 3). Systolic blood pressures were taken at every stage.

Results. Compared to baseline left ventricular end diastolic volume (p——0,001), left atrial area ( p-—0,003), fi›eak early mitral Doppler filling velocity ( fi›——0,01) and systolic blood pressures (|o——0,001) were changed as a result of preload a/tering maneuvers. Only left ventricu- lar myocardial velocities during early filling were signif- icantly unaffected by f›reload altering maneuvers.

Conclusion. In contrast to standard transmitral Doppler filling indices, Doppler tissue early diastolic ve/ocities are not significant/y affected by physiological preload altering maneuvers. Thus, Doppler tissue veloc- ities during early left ventricular diastole may be more useful as an index of diasto/ic function by fi›roviding a fiireIoad-inde[:iendent assessment of left ventricular fill- ing.

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References

  • 1. Grossbman W, Mc Laurin LP, Rolett EL, et al. Alterations in left ventricular relaxation and diastolic compliance in congestive cardiomyopathy. ardiovasc Res 1979; 13:514-22.
  • 2. Doughertiy AH, Nacarelli GV, Gray EL, et al. Congestive heart failure with normal systolic function. Am | Cardiol 1984; 54:778-82.
  • 3. Grossman W. Diastolic dysfunction and congestive heart failure. Circulation 1990; 81 Suppl Ili:H1- 1:7.
  • 4. Grossman W, Mc Laurin LP. Diastolic properties of the left ventricle. Ann Intern Med 1976; 84:316-26.
  • 5. Beonow RO, Bacharach SL, Green MV, et al. impaired left ventricular diastolic filling in patients with coronary artery disease; assessment with radionuclide o angiography. Circulation 1981; 64:315-23.
  • 6. Ishiada Y, Meisner JS, Tsujioka K, et al. Left ventric- ular filling dynamics: influence of left ventricular relaxation and left atrial pressure. Circulation 1986; 74:187-96.
  • 7. Weiss Jl, Fredriksen JW, Weisfeldt ML. Hemodynamic determinants of the time-course of fall in canine left ventricular pressure. | Clin invest 1976; 58:751-61.
  • 8. Nishimura RA, Abel MD, Hatle LK, et al. Assessment of diastolic function of the heart: background and current applications of Döppler echocardiography. Part Il. Clinical studies Mayo Clin Proc 1989; 64:181-204.
  • 9. Thomas JD, Weyman AE. Echo Doppler evaluation of left ventricular diastolic function: Physics and Physiology, Circulation 1991; 84:990-97.
  • 10. Appleton CP, Hatle LK, Pop RL. Relation of transmitral flow velocity patterns to (o left veniricular diastolic function: new insights from a combined hemodynamic and Doppler echocardio-graphic study. | Am Coll Cardiol 1988; 12:426- 40.
  • 11. Hoit BD, Walsh RA. Diastolic function in hypertensive heart disease. In: Gaasch WH, Le Winter M, editors. Left Ventricular Diastolic Dysfunction and Heart Failure. Philadelphia: Lea and Febiger 1994; 354-72.
  • 12. Labowitz AJ, Pearson AC. Evaluation of left ventricular diastolic function: clinical relevance and recent Doppler echocardiographic insights. Am Heart ) 1987; 114:836-51.
  • 13. Choong CY, Hermann HC, Weyman AE, et al... Preload dependence of Doppler derived indexes of left ventricular diastolic function in humans. | Am Coll Cardiol 1987; 10:800-08.
  • 14. Gardin JM, Rohan MK, Davidson DM. Doppler transmitral flow velocity parameters: relation between age, body surface area, blood pressure and gender in normal subjects. Am | Noninvasive Cardiol 1987; 1:3-10.
  • 15. Küo LC, Ouinones MA, Rokey R, et al. Ouantification of atrial contribution to left ventricular filling by pulsed Doppler echocardiography and the effect of age in normal and diseased hearts. Am | Cardiol 1987; 59:1174-78.
  • 16. Appleton CP, Hatle LK. The natural history of left ventricular filling abnormalities: assessment by two dimensional and Doppler echocardiography. Echocardiography 1992; 9:437-45.
  • 17. Choong CY, Abascal VM, Thomas JD, et al. Combined influence of ventricular loading and relaxation on the transmitral flow velocity profile in dogs measured by Doppler echocardiography. Circulation 1988; 78:672-83.
  • 18. Colan SD, Borrow KM, Neumann A. Effects of loading conditions and contractile state (methoxamine and dobutamine) on left ventricular early diastolic function in normal subjects. Am | Cardiol 1985; 55:790-96.
  • 19. Sutherland GR, Stewart MJ, Groundstroem KWE, et al. Color Doppler myocardial imaging: a new technigue for the assessment of myocardial function . J Am Soc Echocardiography 1994; 7:441-58.
  • 20. Miyatake K, Yamagishi M, Tanaka N, et al. New method for evaluating left ventricular wall motion by color-coded tissue Doppler imaging: in vitro and in vivo studies. J Am Coll Cardiol 1995; 25:717-24,
  • 21 . Donovan CL, Armstrong wf, Bach DS. Ouantitative Doppler tissue imaging of the left ventricular myocardium: validation in normal subjects. Am Heart | 1995; 130:100-04.
  • 22. Uematsu M, Miyatake K, Tanaka N, et al. Myocardial velocity gradient as a new indicator of regional left ventricular contraction: detection by a two dimensional tissue Doppler imaging technigue. | Am Cardiol 1995; 26:217-23.
  • 23. Gorscan J 3d, Gulati VK, Mandarino WA, et al. Color coded measures of myocardial velocity throughout the cardiac cycle by tissue Doppler imaging to guantify regional left ventricular function. Am Heart | 1996; 131:1202-13.
  • 24. Isaaz K, Munoz del Romeral L, et al. Ouantification of the motion of the cardiac base in normal subjects by Doppler echocardiography. J Am Soc Echocardiography 1993; 6:166-76.
  • 25. Rodriguez L, Garcia MG, Ares M, et al. Assessment of mitral annular dynamics during diastole by Doppler tissue imaging: Comparison with mitral Doppler inflow in subjecis without heart disease and in patients with left veniricular hypertrophy. Am Heart J 1996; 131:982-87.
  • 26.Garcia MG, Rodriguez 1, Ares M, et al. Differentiation of constrictive pericarditis from restrictive cardiomyopathy: assessment of eft ventricular diastolic velocities in longitudinal axis by Doppler tissue imaging. ) Am Coll Cardiol 1996; 27:108-14.
  • 27. Sohn DW, Chai IH, Lee DJ, et al. Assessment of mitral annulus velocity by Doppler tissue imaging in the evaluation of left ventricular diastolic function . | Am Coll Cardiol 1997; 30:474-80.
  • 28. Aranda JM, Weston MW, Puleo JA, et al. Effect of loading conditions on myocardial relaxation velocities “determined by Doppler tissue imaging in Heart Transplant recipients. | Heart Lung Transplant 1998; 17:693-97.
  • 29. Lundbrook P, Byrne |, Jurnik R, et al. Influence of reduction of preload and afterload by nitrogiycerin on left ventricular diastolic pressure-volume relations and relaxation in man. Circulation 1977; 56:937-43.
  • 30. Stoddard M, Pearson A, Kern M, et al. Influence of alteration in preload on the pattern of left ventricular diastolic filling as assessed by Doppler echocardiography in humans. Circulation 1989; 79:1226-36.
  • 31. Thomas JD, Choong CYP, Flachskampf FA, et al. Analyşis of the early transmitral Doppler velocity curve: effecis of primary physiologic changes arid compensatory preload adjustment. J Am Coll Cardiol 1990; 16:644-55.
  • 32. Brun P, Tribwilly C, Duval AM. Left ventricular flow propagation during early filling is related to wall relaxation: a colour M-mode Doppler analysis. |) Am Coll Cardiol 1992; 20:420-32.
  • 33. Stügaard M, Smseth OCA, Risoe C, et al. Intraventricular early diastolic filling during acute myocardial ischemia, assessment by multigated color M-mode Doppler echocardiography. Circulation 1993; 88:2705-13.
  • 34. Takatsuji H, Mikami T, Urasawa K, et al. A new approach for evaluation of left ventricular diastolic function: spatial and temporal analysis of left ventricular filling flow propagation by color M-mode Doppler echocardiography. | Am Coll Cardiol 1996; 27:365-71.

DOPPLER DOKUSU ERKEN SOL VENTRİKÜL DOLUM HIZI ÖN YÜKLEME, ÖN YÜKLEMEYİ DEĞİŞTİREN MANEVRALARDAN BAĞIMSIZ MIDIR?

Year 2001, Volume: 54 Issue: 3, 205 - 210, 30.09.2001
https://izlik.org/JA79XF88HL

Abstract

Amaç: Transmitral Doppler akım verileri diyastolik fonksiyonu değerlendirmek için kullanılmıştır. Son za- manlarda, Doppler doku kızları sol ventrik’ül gevşemesi- nin bir göstergesi gi/7i kullanılmıştır. Bu çalışmada Dopp- ler doku hızlarının ön y”ük degiştirici manevralardan et- kilenifiı etkilenmediğinin saPtanması amaçlandı.

Yöntem: 17 hastada (t”ümü erkek, 49 x 8) ekokardiyog- raFık sol ventrik”ûl miyokardiyum hızları ölü”ümlerini ya- parken sol ventrik’ül ön y”dk”ünü değiştirdik Trendelen- burg (l. basamak), ıers Trendelenburg (2. basamak) and amil nitrat (3. basamak) ön y’ilk deyiştirici manevralar olarak kullanıldı. Her basamak için sistolik kan basıncı ölç‘üld”ü.

Sonuçları Baş/ang/ç ile karşılaştırılınca, soJ ventrikıfil diyastol hacmi (p-—0,001), sol atriyum alanı ([:›——0,003), [:›ik erken mitra/ Doppler dolum hızı (p—-0,001) ve sisto- Iik kan basınçları (p——0,001) ön yük değiştirici manevra- lar ile değişti, ancak sol ventrik”ül miyokardı hızı erken dolumda ön y”ük defi,iştirici manevralar ile anlamlı değiş- medi.

Yorum• Mitral seviyeden Do[:ıpler dolum verilerinin tersine, Dopfi›ler doku erken diyastol hızları fizyolojik ön y'ük değişfirici manevralardan önemli derecede etkilen- mez. Böylece erken sol ventrik’ül diyastolu sırasında Doppler doku hız/arı sol ventrikü/ diyastolu sırasında DoPpler doku hızları sol ventrik”dl dolumunun ön y'ük- den bağımsız değerlendirilmesini sağlayan daha yararlı bir g”dsterge olabilir.

Project Number

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References

  • 1. Grossbman W, Mc Laurin LP, Rolett EL, et al. Alterations in left ventricular relaxation and diastolic compliance in congestive cardiomyopathy. ardiovasc Res 1979; 13:514-22.
  • 2. Doughertiy AH, Nacarelli GV, Gray EL, et al. Congestive heart failure with normal systolic function. Am | Cardiol 1984; 54:778-82.
  • 3. Grossman W. Diastolic dysfunction and congestive heart failure. Circulation 1990; 81 Suppl Ili:H1- 1:7.
  • 4. Grossman W, Mc Laurin LP. Diastolic properties of the left ventricle. Ann Intern Med 1976; 84:316-26.
  • 5. Beonow RO, Bacharach SL, Green MV, et al. impaired left ventricular diastolic filling in patients with coronary artery disease; assessment with radionuclide o angiography. Circulation 1981; 64:315-23.
  • 6. Ishiada Y, Meisner JS, Tsujioka K, et al. Left ventric- ular filling dynamics: influence of left ventricular relaxation and left atrial pressure. Circulation 1986; 74:187-96.
  • 7. Weiss Jl, Fredriksen JW, Weisfeldt ML. Hemodynamic determinants of the time-course of fall in canine left ventricular pressure. | Clin invest 1976; 58:751-61.
  • 8. Nishimura RA, Abel MD, Hatle LK, et al. Assessment of diastolic function of the heart: background and current applications of Döppler echocardiography. Part Il. Clinical studies Mayo Clin Proc 1989; 64:181-204.
  • 9. Thomas JD, Weyman AE. Echo Doppler evaluation of left ventricular diastolic function: Physics and Physiology, Circulation 1991; 84:990-97.
  • 10. Appleton CP, Hatle LK, Pop RL. Relation of transmitral flow velocity patterns to (o left veniricular diastolic function: new insights from a combined hemodynamic and Doppler echocardio-graphic study. | Am Coll Cardiol 1988; 12:426- 40.
  • 11. Hoit BD, Walsh RA. Diastolic function in hypertensive heart disease. In: Gaasch WH, Le Winter M, editors. Left Ventricular Diastolic Dysfunction and Heart Failure. Philadelphia: Lea and Febiger 1994; 354-72.
  • 12. Labowitz AJ, Pearson AC. Evaluation of left ventricular diastolic function: clinical relevance and recent Doppler echocardiographic insights. Am Heart ) 1987; 114:836-51.
  • 13. Choong CY, Hermann HC, Weyman AE, et al... Preload dependence of Doppler derived indexes of left ventricular diastolic function in humans. | Am Coll Cardiol 1987; 10:800-08.
  • 14. Gardin JM, Rohan MK, Davidson DM. Doppler transmitral flow velocity parameters: relation between age, body surface area, blood pressure and gender in normal subjects. Am | Noninvasive Cardiol 1987; 1:3-10.
  • 15. Küo LC, Ouinones MA, Rokey R, et al. Ouantification of atrial contribution to left ventricular filling by pulsed Doppler echocardiography and the effect of age in normal and diseased hearts. Am | Cardiol 1987; 59:1174-78.
  • 16. Appleton CP, Hatle LK. The natural history of left ventricular filling abnormalities: assessment by two dimensional and Doppler echocardiography. Echocardiography 1992; 9:437-45.
  • 17. Choong CY, Abascal VM, Thomas JD, et al. Combined influence of ventricular loading and relaxation on the transmitral flow velocity profile in dogs measured by Doppler echocardiography. Circulation 1988; 78:672-83.
  • 18. Colan SD, Borrow KM, Neumann A. Effects of loading conditions and contractile state (methoxamine and dobutamine) on left ventricular early diastolic function in normal subjects. Am | Cardiol 1985; 55:790-96.
  • 19. Sutherland GR, Stewart MJ, Groundstroem KWE, et al. Color Doppler myocardial imaging: a new technigue for the assessment of myocardial function . J Am Soc Echocardiography 1994; 7:441-58.
  • 20. Miyatake K, Yamagishi M, Tanaka N, et al. New method for evaluating left ventricular wall motion by color-coded tissue Doppler imaging: in vitro and in vivo studies. J Am Coll Cardiol 1995; 25:717-24,
  • 21 . Donovan CL, Armstrong wf, Bach DS. Ouantitative Doppler tissue imaging of the left ventricular myocardium: validation in normal subjects. Am Heart | 1995; 130:100-04.
  • 22. Uematsu M, Miyatake K, Tanaka N, et al. Myocardial velocity gradient as a new indicator of regional left ventricular contraction: detection by a two dimensional tissue Doppler imaging technigue. | Am Cardiol 1995; 26:217-23.
  • 23. Gorscan J 3d, Gulati VK, Mandarino WA, et al. Color coded measures of myocardial velocity throughout the cardiac cycle by tissue Doppler imaging to guantify regional left ventricular function. Am Heart | 1996; 131:1202-13.
  • 24. Isaaz K, Munoz del Romeral L, et al. Ouantification of the motion of the cardiac base in normal subjects by Doppler echocardiography. J Am Soc Echocardiography 1993; 6:166-76.
  • 25. Rodriguez L, Garcia MG, Ares M, et al. Assessment of mitral annular dynamics during diastole by Doppler tissue imaging: Comparison with mitral Doppler inflow in subjecis without heart disease and in patients with left veniricular hypertrophy. Am Heart J 1996; 131:982-87.
  • 26.Garcia MG, Rodriguez 1, Ares M, et al. Differentiation of constrictive pericarditis from restrictive cardiomyopathy: assessment of eft ventricular diastolic velocities in longitudinal axis by Doppler tissue imaging. ) Am Coll Cardiol 1996; 27:108-14.
  • 27. Sohn DW, Chai IH, Lee DJ, et al. Assessment of mitral annulus velocity by Doppler tissue imaging in the evaluation of left ventricular diastolic function . | Am Coll Cardiol 1997; 30:474-80.
  • 28. Aranda JM, Weston MW, Puleo JA, et al. Effect of loading conditions on myocardial relaxation velocities “determined by Doppler tissue imaging in Heart Transplant recipients. | Heart Lung Transplant 1998; 17:693-97.
  • 29. Lundbrook P, Byrne |, Jurnik R, et al. Influence of reduction of preload and afterload by nitrogiycerin on left ventricular diastolic pressure-volume relations and relaxation in man. Circulation 1977; 56:937-43.
  • 30. Stoddard M, Pearson A, Kern M, et al. Influence of alteration in preload on the pattern of left ventricular diastolic filling as assessed by Doppler echocardiography in humans. Circulation 1989; 79:1226-36.
  • 31. Thomas JD, Choong CYP, Flachskampf FA, et al. Analyşis of the early transmitral Doppler velocity curve: effecis of primary physiologic changes arid compensatory preload adjustment. J Am Coll Cardiol 1990; 16:644-55.
  • 32. Brun P, Tribwilly C, Duval AM. Left ventricular flow propagation during early filling is related to wall relaxation: a colour M-mode Doppler analysis. |) Am Coll Cardiol 1992; 20:420-32.
  • 33. Stügaard M, Smseth OCA, Risoe C, et al. Intraventricular early diastolic filling during acute myocardial ischemia, assessment by multigated color M-mode Doppler echocardiography. Circulation 1993; 88:2705-13.
  • 34. Takatsuji H, Mikami T, Urasawa K, et al. A new approach for evaluation of left ventricular diastolic function: spatial and temporal analysis of left ventricular filling flow propagation by color M-mode Doppler echocardiography. | Am Coll Cardiol 1996; 27:365-71.
There are 34 citations in total.

Details

Primary Language English
Subjects Cardiovascular Medicine and Haematology (Other)
Journal Section Research Article
Authors

Mehmet Fatih Yalçın

Project Number -
Publication Date September 30, 2001
IZ https://izlik.org/JA79XF88HL
Published in Issue Year 2001 Volume: 54 Issue: 3

Cite

APA Yalçın, M. F. (2001). IS DOPPLER TISSUE EARLY LEFT VENTRICULAR FILLING VELOCITY PRELOAD INDEPENDENT OF PRELOAD ALTERING MANEUVERS? Ankara Üniversitesi Tıp Fakültesi Mecmuası, 54(3), 205-210. https://izlik.org/JA79XF88HL
AMA 1.Yalçın MF. IS DOPPLER TISSUE EARLY LEFT VENTRICULAR FILLING VELOCITY PRELOAD INDEPENDENT OF PRELOAD ALTERING MANEUVERS? Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2001;54(3):205-210. https://izlik.org/JA79XF88HL
Chicago Yalçın, Mehmet Fatih. 2001. “IS DOPPLER TISSUE EARLY LEFT VENTRICULAR FILLING VELOCITY PRELOAD INDEPENDENT OF PRELOAD ALTERING MANEUVERS?”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 54 (3): 205-10. https://izlik.org/JA79XF88HL.
EndNote Yalçın MF (September 1, 2001) IS DOPPLER TISSUE EARLY LEFT VENTRICULAR FILLING VELOCITY PRELOAD INDEPENDENT OF PRELOAD ALTERING MANEUVERS? Ankara Üniversitesi Tıp Fakültesi Mecmuası 54 3 205–210.
IEEE [1]M. F. Yalçın, “IS DOPPLER TISSUE EARLY LEFT VENTRICULAR FILLING VELOCITY PRELOAD INDEPENDENT OF PRELOAD ALTERING MANEUVERS?”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 54, no. 3, pp. 205–210, Sept. 2001, [Online]. Available: https://izlik.org/JA79XF88HL
ISNAD Yalçın, Mehmet Fatih. “IS DOPPLER TISSUE EARLY LEFT VENTRICULAR FILLING VELOCITY PRELOAD INDEPENDENT OF PRELOAD ALTERING MANEUVERS?”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 54/3 (September 1, 2001): 205-210. https://izlik.org/JA79XF88HL.
JAMA 1.Yalçın MF. IS DOPPLER TISSUE EARLY LEFT VENTRICULAR FILLING VELOCITY PRELOAD INDEPENDENT OF PRELOAD ALTERING MANEUVERS? Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2001;54:205–210.
MLA Yalçın, Mehmet Fatih. “IS DOPPLER TISSUE EARLY LEFT VENTRICULAR FILLING VELOCITY PRELOAD INDEPENDENT OF PRELOAD ALTERING MANEUVERS?”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 54, no. 3, Sept. 2001, pp. 205-10, https://izlik.org/JA79XF88HL.
Vancouver 1.Yalçın MF. IS DOPPLER TISSUE EARLY LEFT VENTRICULAR FILLING VELOCITY PRELOAD INDEPENDENT OF PRELOAD ALTERING MANEUVERS? Ankara Üniversitesi Tıp Fakültesi Mecmuası [Internet]. 2001 Sept. 1;54(3):205-10. Available from: https://izlik.org/JA79XF88HL