Periferik Stem Hücre Transplantasyonu

Abstract

PSHT’u konvansiyonel tedavilerin etkili olmadigi malign ve non- malign birgok hematolojik hastahklarda kullanilan bir tedavi yaklasi- midir. Her yasta uygulanabilmesi, donor riskinin az olmasi, erken he- matolojik rekonstitiisyon saglamasi, immun rekonstittisyonun cabuk ve stabil olmasi, relatif olarak ucuz, bir tedavi secenegi olmasi, hospi- talizasyon stiresinin kisa olmasi ve kemik iligi tutulumu olan vakalar

Keywords

• kemik iligi transplantasyonu
• donor
• periferik stem hiicre

PERIFERIK STEM HUCRE TRANSPLANTASYONU

Abstract

PSHT’u konvansiyonel tedavilerin etkili olmadigi malign ve non- malign birgok hematolojik hastahklarda kullanilan bir tedavi yaklasi- midir. Her yasta uygulanabilmesi, donor riskinin az olmasi, erken he- matolojik rekonstitiisyon saglamasi, immun rekonstittisyonun cabuk ve stabil olmasi, relatif olarak ucuz, bir tedavi secenegi olmasi, hospi- talizasyon stiresinin kisa olmasi ve kemik iligi tutulumu olan vakalar

Keywords

• donor
• . periferik stem hiicre
• kemik iligi transplantasyonu

References

1. 1.Appelbaum FR Thomas ED . Treatment of acute leukemia in adults with chemoradiotherapy and bone marrow transplantation. Cancer 55 ; 2203-2209, 1985.
2. 2.Arlin ZA Fried J Ciarkson BD et al: Therapeutic role of cell kinetics in acute leukemia, Clin Haem 7 : 339-362, 1978.
3. 3.Espigado I Rodriguez JM Carmona M et al : Peripheral blood stem cell collection : Comparision of two protocols. Bone Marrow Transplant 5 (Suppl 1) ; 32, 1990.
4. 4.Goldman JM : Autogrefting croyopreserved buffy coat cells for chronic granulocytic lenkemia in transformation. Exp Haem 7 (Suppl 5) - 389-393, 1979.
5. 5.Iacone A Dragani A Quagliette AM et al : Collection of blood derived hematopoietic stem cells with a CS 3000 blood cell separator. Bone Marrow Transplant 5 (Suppl 1) : 70, 1990.
6. 6.Jones RJ Celano P Sharkis SJ et al : Two phases of engrafment established by serial bone marrow transplantation. Blood 73 (2) : 397-401, i989.
7. 7.Jutiner CA To LB Haylock DN et al : Circulating autologous stem cells coliected in very early remission from ANLL produce prompt but incomplete hematological reconstitution after high dose melphalan and supralethal chemoradiotherapy. Br J Haem 61 : 739-746, 1985,
8. 8.Kessinger A Armitage JO Smith DM et al; High-dose therapy and autologous peripheral stem cel) transplantation for patients with lymphoma. Blood 74 (4) 1260-1265, 1989.

9. 9.Kessinger A Schmit-Pokorny K Smith D et al : Cryopreservation and infusion of autologous peripheral stem cells. Bone Marrow Transplant 5 (Suppl 1) : 25-27, 1990.
10. 10.Kiessel S Pezutto A Korbling M et al : Autologous peripheral blood stem cell transplantation. Analysis of autografted cells and lymphocyte recovery. Transplant Proc 21 (1) : 3084-3088, 1989,
11. 11.Korbling M Haas R Knauf W et al : Therapeutic efficacy of autologous blood stem cell transplantation (ABSCT) : the role of cytotoxic/cytokine stem cell mobilization. Bone Marrow Transplant 5 (Suppl 1) : 39-40, 1999.
12. 12.Reiffers J Bernard PH Marit G et al . Collection of blood derived hematopoietic stem cells and application for autologous transplantation, Bone Marrow Transplant 1 (Suppl 1) : 371-372, 1986.
13. 13.Richman GM Weiner RS Yankee RA et al: Increase in circulating stem cells following chemotherapy in man. Blood 47 : 1031-1035, 1978.
14. 14.Socinski MA FMas A Lowell S et al: Granulocyte-Macrophage colony stimutating factor expands the circulating hemapoietic progenitor cell compartment in man. Lancet 28 : 1194-1198, 1988.
15. 15.Schultze W Richter E Matthes H et al: Processing and quality control of peripheral stem cell grafts. Bone Marrow Transplant 10 (Suppl 2) : 44, 1992.
16. 16..Sardag OS Uysal VA Kog H ve ark , Konvansiyonel tedavilerin etkili olmadig1 solid tlimdérlerde yiksek doz kemoterapi ile birlikte kryoprezerve otolog kemik iligi transplantasyonu. Cer. Tip Fak. Derg. 20 ; 441-448, 1989.
17. 17..Sardas OS Uysal VA Kog H ithan © : Kicik hiicreli akciger kanserlerinde yiksek doz kemoterapi ve otolog kemik ilixi transplantasyonu. Ege Univ. Tip Fak. Dergisi 28 (4) : 1763-1772, 1989.
18. 18Proceedings of the Symposium on high Dose Chemotherapy and Stem Cell Transplantation in Solid Tumors. May 4-6, 1992, Berlin Germany, Bone Marrow Transp 10 (Suppl 2) : 1-62, 199