Toplumumuzda Üriner Sistem Taş Hastalığında Hiperparatroidizm İnsidansı (104 Olguda)

Abstract

Tas hastalginin etyolojisinde hiperkalsemi ve hiperkalsiurinin, dénemli bir yer tuttugu bilinmektedir. Hiperparatiroidizm de hiperkalsemi ve hiperkalsitirinin belirgin nedenleri arasindadir. Bu calismada klinikte yatan 104 tiriner sistem tas hastasinda hiperparatiroidi insidansi arastinidi. Tim hastalarda iki kez olmak tizere serum kalsiyum ve fosfor tayinleri yapuld.. Hiperkalsemi tespit edilen 21 olguda (% 20.1), serum parathormon degerleri arashirud. Bu hastalarm 4’Unde (% 3.8) serum parathormon degerleri yuksek bulundu. Parathormon seviyesi yoksek olan hastalarm birinde paratiroid hiperplazisi, birinde ise paratiroid adenomu ultrasonografik ve sintigrafik clarak tesbit edildi. Bu calismamuzda elde edilen sonuca gére; iiriner sistem tag hastahgi olan hastalarda serum kalsiyum ve fosfor diizeyleri kriter almarck, peratireid patolojilerinin etyolojik neden olarak arastirilmasi tedavi ve takipte bize 1gik tutabilecektir.

Keywords

• üriner
• taş
• hiperparatriodizm

TOPLUMUMUZDA URINER SISTEM TAS HASTALIGINDA HIPERPARATROIDIZM INSIDANSI (104 OLGUDA)

Abstract

Hypercalcemia and hypercalciuria are the most important etiologic factors in urolithiasis. Hyperparathyroidsm as a cause of hypercalcemia and hypercalciuria are also important as etiologic factors. In this study, we have evaluated the incidence of primary hyperparathyroidsm in 104 patients with urinary stone diseased twice for each patient. Hypercalcemia has been found in 21 (20.1 %) patients and in 4 of these patients (8.8 %) serum parathormon concentrations have been evaluated. Parathyroid hyperplasia and parathyroidadenoma have been demostrated scintigraphycaly and ultrasoundgraphycaly in two of these patients. Serum calcium and phosfor concentrations must be measured in urinary stone disease and parathyroid pathologies must also be searched as etiologic factors.

Keywords

• üriner
• taş
• hiperparatriodizm

References

1. 1 Broadus EA : Primary Hyperparathyroidism, J. Urol, 141 723-728, 1989.
2. 2 Fuss M Pepersack T Corvilain J et al : Infrequency of Primary Hyperparathyroiddsm in Renal Stone Formers: Brit. J. Urol, 62, 4-6, .1988.
3. 3 Malette LE Bilezikian JP Heath DA et al: Primary Hyperparathyroidism : Biochemical and Clinical Features : Medicine, 127-146, 1972.
4. 4 McGeown MG : Effect of Parathyroidectomy on the Incidance of Renal Calculi; Lancet, 1, 586-587, 1961.
5. 5 Meacock P Robertson WG Nordin BEC : Relation Between Serum and Urinary Calcium with Particular to Parathroyroid Activity; Lancet, 1, 384-386, 1969.
6. 6 Pak CYC Nicar JM Peterson R et al: A Lack of Unique Pathophysiologic Background for Nephrolithiasis of Primary Hyperparathyroidism; J. Cli End Met, 53, 536-542, 1981.
7. 7 Parks J Coe F Favus M Hyperparathroidism in Nephrolithiasis; Arch Intern Med, 140, 1476-1481, 1980.
8. 8 Roonstra CE Jackson CE : Hyperparathyoidism Detected by Routine Serum Calcium Analysis : Prevalance in a Clinical Population, Ann Intern Med; 63, 468-474, 1963.

9. 9 Spirnak PJ Resnick IM : Urinary Stones, Primary Care, 12, 735-759, 1985.
10. 10 Tonagho EA McAninch JW : General Urology, Lange Medical Publications, 275- 301, 1988.
11. 11 Walsh P Gittes P Perlmutter A Stamey T ; Campells Urology, Saunders Company, 1094-1172, 1986.