Insan Lokosıt Antıjenlerı Ve Perıyodık Hastalık
Abstract
One of the most remarkable discoveries in recent years is the involment of the major histocompatibility complex in immunologic reactions. set of The human leucocyte antigens (HLA) system represents a similar genes in man and comprises 5 closely linked genetic loci on chromosome 6. Transplantation antigens coded for the HLA-A, HLA-B, HLA-C, HLA-C and HLA-DR loci are readly idendified with the use of serologic technic. The connection with a particular HLA type may make it possible to In
distinguish different clinical forms of a disease. some disease the HLA region served as a genetic marker for recessive or dominantly inherid disease genes. Gen frequency and disease association differ in different geographic regions. In this investigation, we have come to conclusion that : Some of HLA antigens, A9, A10, Bis and B4o antigens showed a, relative risk, although it was at a lower rate, compared with the other types antigens. It will be possible to attain a more meaningful result as the number of cases increase.
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References
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