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Hyperprolactinemia in Polycystic Ovarian Disease

Year 1988, Volume: 41 Issue: 3, 541 - 546, 31.10.1988
https://izlik.org/JA67NL45RH

Abstract

Hyperprolactinemia is seen approximately in 1/3 of the patients who have Polyeystic Ovarian Disease (PCOD). The etiology of high serum prolactin levels is not so clear. The serum prolactin levels were measured in 9 patients who had PCOD with hyperprolactinemia andin 5 patients who had oligomenorrhea but no high levels of serum prolactin as a control group, after the administration of Clomiphene Citrate. The serum prolactin levels were found normal. The decrease of serum prolactin levels after the administration of Clomiphene Citrate was thought that, high serum estradiol levels have a significant role in the etiology of hyperprolactinemia in the patients who have PCOD.

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References

  • 1. Bahamondes L., Faundes A, Tabascia A., Tambascia M., Trevison M., Dachs J.N., Pinotti JA. : Mensirnal pattern and ovarian function in women with hyperprolactinemia. Int. J. Gynacol. Obstet. 23 : 31, 1985.
  • 2. Blum 1, Bruhis S., Kauflman H. : Clinical evaluation of the effects of combined treatment with bromocriptine and spironolactone in two women with the polycystic ovary syndrome. Fertil. Steril, 35 : 629, 1981.
  • 3. Corenblum B., Taylor J. : The hyperprolactinemic polyoystic ovary syndrome may not be a distinct entity. Fertil. Steril. 38 : 549, 1982.
  • 4, Corenblum B, Taylor P.J. : Idiopathic hyperprolactinemia may include a distinct entity with a natural history different from that of prolactin adenomas. Fertil, Steril, 49 : 544, 1988.
  • 5, Falasehi P., DelPoze E., Rocce A., Toscane V., Petrangeli E., Pompei P., Fajase G. : Prolactin release in polycystic ovary. Obstet .Gynecol. 55 : 579, 1980.
  • 6. Goldzieher D.W. ; Polyeystic ovarlan disease. Fertil. Steril. 35 ; 371, 1931.
  • 7. Healy D.I., Burger G.H. : Serum follicle stimulating hormone and prolactine during the induction ol ovulâtion with exogenous gonadotropin. J. Cün. Endocrinol, Metab. 56 : 474, 1983.
  • 8. Kato J. Kobayashi T., Willee C.A. : Effect of clomiphene on the uptake of estradiol by the anterior hypothalamus and hypohysis. Endocrinology. 82 : 1049, 1968.
  • 9. Kim MH, Chang FE. : Chronic anovulation. Clin, Obstet. Gynecol. 27 : 941, 1984.
  • 10. Luciano A.A, chapler F.K. Sherman B.M. : Hyperprolactinemia in polycstic ovary syndrome, Fertil. Steril. 41 : 719, 1984.
  • 11.MacDonald P.C, Edman C.D. Hemsell DI., Porter J.C,, Siiteri P.K. : Effect of obesity on coniversion of plasma androsteronedino to estrone in postmenopasual Women with and without endometrial cancer, Am. J. Obstet. Gynecol. 130 ; 448, 1978,
  • 12.Mikkelson T.J., Baustran C.1., Cameron W.J, : Preliminary report of the disposition of clomiphene in healty human subjects. Fertil. Steril. 41 : 935, 1984.
  • 13.Rebar R., Judd H.L., Yen 5.5.C,, Rakoff J., Vandenberg G. Naftolin F. : Characterization of the inappropriate gonadotropin secretion in polycystic ovary syndrome. J, Clin. İnvest. 57 : 1320, 1976.
  • 14.Reid R.L., Fretts R., VanVugt D.A. : The theory and practise of ovulation induction with gonadotropin-releasing hormone, Am. J. Obstet. Gynecol. 158 176,1988.
  • 15.Reinthaller A., Bieglmayer C., Deutinger J., Csaicsich P. : Transient hyperprolactinemia during cycle stimulation : Influence on the endocrine response and fertilization rate of human oocytes and effect of bromocriptine treatment. Fertil. Steril. 49 : 432., 1988.
  • 16.Rosen G.F., Lobo R.A. : Further evidence against deponine deficiency as then cause of inappropriase gonadotropin secretion in patients with polyoystic ovary syndrome. J, Clin. Endoc. Metabol. 65 : 891, 1987.
  • 17.Seki K., Seki M.. Okumura T. ; Effect of clomiphone citrate on serum prolactine in infertile women with ovarian dysfonction. Am. J. Obstet, Gynecol. 124 ; 125, 1978.
  • 18.Yen S.5.C. : The polyeystic ovary syndrome. Clin. Endocrinol. 12 : 177, 1980.

Polikistik Over Hastalığında Hiperprolaktinemi

Year 1988, Volume: 41 Issue: 3, 541 - 546, 31.10.1988
https://izlik.org/JA67NL45RH

Abstract

Polikistik Over Hastalığı olan hastaların yaklaşık 1/3 ünde hiperprolaktinemi görülmektedir. Bu prolaktin yükselişinin etyolojisi tam
aydınlanmamıştır. Polikistik Over Hastalığı ile birlikte hiperprolaktinemili 9 hasta ve hiperprolaktinemisi olmayan oligomenoreli 5 kontrol vakasında
Clomiphene Citrate uygulamasından sonra serum prolaktin ölçümleri yapıldı ve bir düşme gözlendi. Clomiphene Citrate sonrası serum prolaktin
değerlerindeki bu düşme Polikistik Over Hastalığında hiperprolaktinemi nedeninin yükselmiş olan östradiol değerleri olabileceğini düşündürür.

Ethical Statement

-

Supporting Institution

-

Project Number

-

Thanks

-

References

  • 1. Bahamondes L., Faundes A, Tabascia A., Tambascia M., Trevison M., Dachs J.N., Pinotti JA. : Mensirnal pattern and ovarian function in women with hyperprolactinemia. Int. J. Gynacol. Obstet. 23 : 31, 1985.
  • 2. Blum 1, Bruhis S., Kauflman H. : Clinical evaluation of the effects of combined treatment with bromocriptine and spironolactone in two women with the polycystic ovary syndrome. Fertil. Steril, 35 : 629, 1981.
  • 3. Corenblum B., Taylor J. : The hyperprolactinemic polyoystic ovary syndrome may not be a distinct entity. Fertil. Steril. 38 : 549, 1982.
  • 4, Corenblum B, Taylor P.J. : Idiopathic hyperprolactinemia may include a distinct entity with a natural history different from that of prolactin adenomas. Fertil, Steril, 49 : 544, 1988.
  • 5, Falasehi P., DelPoze E., Rocce A., Toscane V., Petrangeli E., Pompei P., Fajase G. : Prolactin release in polycystic ovary. Obstet .Gynecol. 55 : 579, 1980.
  • 6. Goldzieher D.W. ; Polyeystic ovarlan disease. Fertil. Steril. 35 ; 371, 1931.
  • 7. Healy D.I., Burger G.H. : Serum follicle stimulating hormone and prolactine during the induction ol ovulâtion with exogenous gonadotropin. J. Cün. Endocrinol, Metab. 56 : 474, 1983.
  • 8. Kato J. Kobayashi T., Willee C.A. : Effect of clomiphene on the uptake of estradiol by the anterior hypothalamus and hypohysis. Endocrinology. 82 : 1049, 1968.
  • 9. Kim MH, Chang FE. : Chronic anovulation. Clin, Obstet. Gynecol. 27 : 941, 1984.
  • 10. Luciano A.A, chapler F.K. Sherman B.M. : Hyperprolactinemia in polycstic ovary syndrome, Fertil. Steril. 41 : 719, 1984.
  • 11.MacDonald P.C, Edman C.D. Hemsell DI., Porter J.C,, Siiteri P.K. : Effect of obesity on coniversion of plasma androsteronedino to estrone in postmenopasual Women with and without endometrial cancer, Am. J. Obstet. Gynecol. 130 ; 448, 1978,
  • 12.Mikkelson T.J., Baustran C.1., Cameron W.J, : Preliminary report of the disposition of clomiphene in healty human subjects. Fertil. Steril. 41 : 935, 1984.
  • 13.Rebar R., Judd H.L., Yen 5.5.C,, Rakoff J., Vandenberg G. Naftolin F. : Characterization of the inappropriate gonadotropin secretion in polycystic ovary syndrome. J, Clin. İnvest. 57 : 1320, 1976.
  • 14.Reid R.L., Fretts R., VanVugt D.A. : The theory and practise of ovulation induction with gonadotropin-releasing hormone, Am. J. Obstet. Gynecol. 158 176,1988.
  • 15.Reinthaller A., Bieglmayer C., Deutinger J., Csaicsich P. : Transient hyperprolactinemia during cycle stimulation : Influence on the endocrine response and fertilization rate of human oocytes and effect of bromocriptine treatment. Fertil. Steril. 49 : 432., 1988.
  • 16.Rosen G.F., Lobo R.A. : Further evidence against deponine deficiency as then cause of inappropriase gonadotropin secretion in patients with polyoystic ovary syndrome. J, Clin. Endoc. Metabol. 65 : 891, 1987.
  • 17.Seki K., Seki M.. Okumura T. ; Effect of clomiphone citrate on serum prolactine in infertile women with ovarian dysfonction. Am. J. Obstet, Gynecol. 124 ; 125, 1978.
  • 18.Yen S.5.C. : The polyeystic ovary syndrome. Clin. Endocrinol. 12 : 177, 1980.
There are 18 citations in total.

Details

Primary Language English
Subjects Obstetrics and Gynaecology
Journal Section Research Article
Authors

Gülşen Vardar This is me

Project Number -
Publication Date October 31, 1988
IZ https://izlik.org/JA67NL45RH
Published in Issue Year 1988 Volume: 41 Issue: 3

Cite

APA Vardar, G. (1988). Hyperprolactinemia in Polycystic Ovarian Disease. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 41(3), 541-546. https://izlik.org/JA67NL45RH
AMA 1.Vardar G. Hyperprolactinemia in Polycystic Ovarian Disease. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1988;41(3):541-546. https://izlik.org/JA67NL45RH
Chicago Vardar, Gülşen. 1988. “Hyperprolactinemia in Polycystic Ovarian Disease”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 41 (3): 541-46. https://izlik.org/JA67NL45RH.
EndNote Vardar G (October 1, 1988) Hyperprolactinemia in Polycystic Ovarian Disease. Ankara Üniversitesi Tıp Fakültesi Mecmuası 41 3 541–546.
IEEE [1]G. Vardar, “Hyperprolactinemia in Polycystic Ovarian Disease”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 41, no. 3, pp. 541–546, Oct. 1988, [Online]. Available: https://izlik.org/JA67NL45RH
ISNAD Vardar, Gülşen. “Hyperprolactinemia in Polycystic Ovarian Disease”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 41/3 (October 1, 1988): 541-546. https://izlik.org/JA67NL45RH.
JAMA 1.Vardar G. Hyperprolactinemia in Polycystic Ovarian Disease. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1988;41:541–546.
MLA Vardar, Gülşen. “Hyperprolactinemia in Polycystic Ovarian Disease”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 41, no. 3, Oct. 1988, pp. 541-6, https://izlik.org/JA67NL45RH.
Vancouver 1.Gülşen Vardar. Hyperprolactinemia in Polycystic Ovarian Disease. Ankara Üniversitesi Tıp Fakültesi Mecmuası [Internet]. 1988 Oct. 1;41(3):541-6. Available from: https://izlik.org/JA67NL45RH