Prostat Kanserli Hastalarda Oriektomi Öncesi Ve Sonrası Serum Hormon Düzeyleri

Year 1986, Volume: 39 Issue: 2, 183 - 194, 30.06.1986

Sezai Yaman

https://izlik.org/JA67PP89PT

Abstract

2 prostat kanserli hasta bütün yönleri ile değerlendirildi. 2 hasta dışında TUR materyeli ile prostat iğne biyopsisinin Histo-Patolojik
bulguları birbirini doğrular durumda idi. Bir olguda biyopsi materyali
BPH geldiği halde TUR materyali adeno Ca olarak saptandı. Bir digerinde de iğne biyopsisi adeno Ca olarak geldiği halde TUR materyali BPH idi. Enzim düzeylerinin tek başına bir tanı değerine sahip
olmadığı gözlendi. Testis dokusunun Histo-Patolojik incelemeleri literatür bulgularına benzerlik gösteriyordu.
Pre-op ve Post-op devrede yapılan plazma testosteron ve estradiol düzeyleri anlamlı bir farklılık gösterdiği tespit edildi. Memleketimizde ilk kez yapılan bu inceleme ile prostat kanserli olgularda
orkiektominin tedavide ve prognozda klasik bilgileri doğrular nitelikte etkili olabileceği kanısına, varıldı.

Keywords

üroloji , kanser , prostat

Serum Hormone Levels in Prostate Cancer Patients Before and After Oriectomy

https://izlik.org/JA67PP89PT

Abstract

12 Cases suffered from prostat cancer were fully assessed. Except
of 2 cases histopathologic examination of TUR and prostatic needle
biopsy materials confirmed to each other, The biopsy material in one
case was observed as BPH, inspite of the histopathologic examination
of TUR material was adeno- Ca in this case. On the other hand, in
another case the needle biopsy was adeno-Ca, although TUR material histologically came as BPH. It was found that enzyme levels had
no diagnostic value. The histopathologic features of testis biopsy materials were similar to those recorded in the literature.
İt was also found that plasma testosterone and estradiol levels
in the pre-op and post-op stage were statistically different. As a first
investigation in our country, the results of the present study are in
agreement with the classically well established observations concerning the validity of orchiectomy in prostatic cancer treatment and
prognosis

Keywords

üroloji , prostat , kanser

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