Case Report

Anesthesia Management in a Rare Case: Wolf-Hirschhorn Syndrome

Volume: 78 Number: 2 July 1, 2025
Özgün Ömer Asiller *, Ezgi Yıldırım , Barış Sakul , Menekşe Özçelik
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Anesthesia Management in a Rare Case: Wolf-Hirschhorn Syndrome

Abstract

Wolf-Hirschhorn syndrome is a rare disease and may cause difficulties in airway management. In addition, intraoperative complications may occur. We will share with you our anesthesia management experience in a patient who is scheduled to undergo repair due to a cleft lip.

Keywords

Wolf-Hirschhorn syndrome, pediatric anesthesia, rare diseases

Project Number

03779

Ethical Statement

Informed Consent: Informed consent was obtained both orally and in writing from the patient’s legal representative.

References

  1. 1. Hirschhorn K, Cooper HL. Chromosomal aberrations in human disease. A review of the status of cytogenetics in medicine. Am J Med. 1961;31:442- 470.
  2. 2. Wolf U, Reinwein H, Porsch R, Schröter R, Baitsch H. [Deficiency on the short arms of a chromosome No. 4]. Humangenetik. 1965;1:397-413.
  3. 3. Battaglia A, Carey JC, South ST. Wolf-Hirschhorn syndrome: A review and update. Am J Med Genet C Semin Med Genet. 2015;169:216-223.
  4. 4. Battaglia A, Filippi T, Carey JC. Update on the clinical features and natural history of Wolf–Hirschhorn (4p-) syndrome: Experience with 87 patients and recommendations for routine health supervision. Am J Med Genet C Semin Med Genet. 2008;148C:246-251.
  5. 5. Gamble JF, Kurian DJ, Udani AG, Greene NH. Airway management in a patient with Wolf-Hirschhorn syndrome. Case Rep Pediatr. 2016;2016:7070125.
  6. 6. Choi JH, Kim JH, Park YC, Kim WY, Lee Y-S. Anesthetic experience using total intra-venous anesthesia for a patient with Wolf-Hirschhorn syndrome-A case report. Korean J Anesthesiol. 2011;60:119-123.
  7. 7. Tsukamoto M, Yamanaka H, Yokoyama T. Anesthetic considerations for a pediatric patient with Wolf-Hirschhorn syndrome: a case report. J Dent Anesth Pain Med. 2017;17:231.
  8. 8. Kim HJ, You JA, Park S, Kim EJ, Park SJ, Kim HY. Anesthetic considerations for an adult with Wolf-Hirschhorn syndrome - A case report. Anesth Pain Med (Seoul). 2020;15:120-123.
  9. 9. Bloor M, Nandi R, Thomas M. Antiepileptic drugs and anesthesia. Paediatr Anaesth. 2017;27:248-250.
  10. 10. Abdallah C. Considerations in perioperative assessment of valproic acid coagulopathy. J Anaesthesiol Clin Pharmacol. 2014;30:7.

Details

Primary Language

English

Subjects

Pediatric Genetic Illnesses

Journal Section

Case Report

Authors

Barış Sakul This is me
0009-0000-9306-0886
Türkiye

Publication Date

July 1, 2025

Submission Date

September 27, 2024

Acceptance Date

June 1, 2025

Published in Issue

Year 2025 Volume: 78 Number: 2

DOI

https://doi.org/10.4274/atfm.galenos.2025.03779

IZ

https://izlik.org/JA35ZF69JD

Cite

RIS / Bibtex
APA
Asiller, Ö. Ö., Yıldırım, E., Sakul, B., & Özçelik, M. (2025). Anesthesia Management in a Rare Case: Wolf-Hirschhorn Syndrome. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 78(2), 164-166. https://doi.org/10.4274/atfm.galenos.2025.03779
AMA
1.Asiller ÖÖ, Yıldırım E, Sakul B, Özçelik M. Anesthesia Management in a Rare Case: Wolf-Hirschhorn Syndrome. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2025;78(2):164-166. doi:10.4274/atfm.galenos.2025.03779
Chicago
Asiller, Özgün Ömer, Ezgi Yıldırım, Barış Sakul, and Menekşe Özçelik. 2025. “Anesthesia Management in a Rare Case: Wolf-Hirschhorn Syndrome”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 78 (2): 164-66. https://doi.org/10.4274/atfm.galenos.2025.03779.
EndNote
Asiller ÖÖ, Yıldırım E, Sakul B, Özçelik M (July 1, 2025) Anesthesia Management in a Rare Case: Wolf-Hirschhorn Syndrome. Ankara Üniversitesi Tıp Fakültesi Mecmuası 78 2 164–166.
IEEE
[1]Ö. Ö. Asiller, E. Yıldırım, B. Sakul, and M. Özçelik, “Anesthesia Management in a Rare Case: Wolf-Hirschhorn Syndrome”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 78, no. 2, pp. 164–166, July 2025, doi: 10.4274/atfm.galenos.2025.03779.
ISNAD
Asiller, Özgün Ömer - Yıldırım, Ezgi - Sakul, Barış - Özçelik, Menekşe. “Anesthesia Management in a Rare Case: Wolf-Hirschhorn Syndrome”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 78/2 (July 1, 2025): 164-166. https://doi.org/10.4274/atfm.galenos.2025.03779.
JAMA
1.Asiller ÖÖ, Yıldırım E, Sakul B, Özçelik M. Anesthesia Management in a Rare Case: Wolf-Hirschhorn Syndrome. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2025;78:164–166.
MLA
Asiller, Özgün Ömer, et al. “Anesthesia Management in a Rare Case: Wolf-Hirschhorn Syndrome”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 78, no. 2, July 2025, pp. 164-6, doi:10.4274/atfm.galenos.2025.03779.
Vancouver
1.Özgün Ömer Asiller, Ezgi Yıldırım, Barış Sakul, Menekşe Özçelik. Anesthesia Management in a Rare Case: Wolf-Hirschhorn Syndrome. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2025 Jul. 1;78(2):164-6. doi:10.4274/atfm.galenos.2025.03779