Klinik Kalp Hastalığı Bulunmayan Diabetes Mellitus'lularda Sol Ventrikül Performansının Sistolik Zaman İntervalleri İle Araştırılması

Abstract

Klinik olarak kalp hastalığının semptom ve bulguları olmayan diabetes mellituslularda preklinik düzeyde myokardial bir disfonksiyonun buunup bulunmadığını saptamak amacıyla 25 diabetli olguyu sistolik zamani ile inceledik. Hiç bir hastalığı olmayan 25 gönüllü de kontrol grubumuzu oluşturdu.

Keywords

• Klinik
• semptom
• intervaller

KLİNİK KALP HASTALIĞI BULUNMAYAN DİABETES MELLİTUS'LULARDA SOL VENTRİKÜL PERFORMANSININ SİSTOLİK ZAMAN İNTERVALLERİ İLE ARAŞTIRILMASI

Abstract

assses theccccccccc performance in diabetes patients without clinical evidence of cardiac involvemeni, and hypertension, obesity, retinal, renal and ncurologic complication, systolic time invervals Were obtained in 25 normal subject and 25 patients With diabetes mellitus. Nine patients Were having insulin, the other nine were having oral hypoglycemic drug and the rest 7 patients were folliwing only diet. Diabetes Was known to be present from one montlı to 10 years. None of the patients had symploms suggestive of angina pectoris. Systolic time intervals Were recorded on ossilographic recorder (Electronic for Medicine DR-12) at a paper speed 200 mm per second with time markers at 0.02 second. Recording was done at least two hours postprandial in afternoon using the method described by Weissler,

Keywords

• left ventricular
• diabetes
• hypertension

References

1. 1.Scott RC : Diabetes and the heart, Amer ! Med 90 : 283, 1975.
2. 2.Krolewski AS, Czyzyk A ve ark : Mortality from cardiovascular diseases among diabetiçs, Diabetologia 13 : 345, 1977
3. 3.Dorümer AC, Shenoy PN v enrk ! Diffuse coronary artery discases in diabetic patienis. Fact or fiction Circulation 57 : 133, 1978
4. 4.Ledet T, Histological and histochemical changes in coronary arteries of old diabetic patients, Diabetologia 4 : 268, 1968
5. 5.Sohar E, Ravid M ve ark : Diabetiç fibrillosis, Amer J Med 49 : 55, 1970
6. 6.Rubler S, Dlugash J, Yüceoğlu YZ ve ark : New type of cardiomyopatlıy associateğ with diabetic glomerulosclerosis, Amer J Cardiol 30 ; 585, 1972
7. 7.Hamby RI, Zoneraich S, Sherman L : Diabetic cardiomyopathy JAMA 229: 1749, 1974
8. 8.Regan TI, Jaferi GA ve ark : Abnormalities of left ventricular function and morphology in diabetes mellitus without evident ischemin, Clin res 22 : 555, 1974 (absir.)

9. 9.Regan TI, Lyons MM ve ark : Evidence for cardiomyopathy in familial diabetes mel- Titus, J Clin invest 60 : 885, 1977
10. 10.Crall FV, Roberts WC : The extramural and intramural coronary arteries in juvenile diabetes mellitus, Amer J Med 64 : 221, 1978
11. 11.D'elia J, Weinrauch LA ve ark : Myacardial dysfunction without coronary arterys disease in diabetic renal failure, Amer J Cardiol, 43 ; 193, 1979
12. 12.Kannel WB, Hjortland M, Caslelli WP : Role of diabets in congestive heart failure, The EFragmingham study, Amer J Cardiol 34 : 79, 1974
13. 13.Ahmed SS, Jaferi GA ve ark : Preclinical abnormality of left ventricular function in diabetes mellitus, Amer Heart J 89: 153, 1975
14. 14.Rubler S, Sajadi RM ve ark ; Noninvasive gslimalilon of myocardial performance in patients witli diabetes, effect of alcohol administration Diabetes 27 : 127, 1978
15. 15.Seneviratne BB : Diabetic cardiomyopathy. The preclinical phase, Brit MedlJl; 1444, 1977
16. 16.Zoneraich S, Zoneraich O, Rhee JJ : Left veniricular performance in diabetic patients without clinical heart disease, Chest 72 : 748, 1977
17. 17.Sanderson JE, Brown DJ ve ark : Diabetic cardiomyopathy. An echocardiographic study of young diabetics, Brit Med J 1 : 404, 1978.
18. 18.Weissler AM, Harris W, Sehoenfeld CD ; Systolic time intervals in heart failure in man, Circulation 37 : 149, 1968
19. 19.Weissler AM, Harris WS, Sohoenfieli CD :; Bedside technics for the evaluation of ventricnlar function in man, Amer J Cardiol 23 : 577 ,1969
20. 20.Spodick DH, Pigott VM ve ark : Preclinical cardiac malfunction in chronic alcoholism New Eng J Med 287 : 677, 1972