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Karaciğerde Hem Ve Hemoprotein Biyosdntezinin Düzenlenmesi

Year 1981, Volume: 34 Issue: 1, 177 - 183, 11.08.1981

Nihat Sipahi

Abstract

Hem sentezinin karaciğer ve eritrositey seri hücreleri dışında da olabileceği gösterilmiştir, Çeşitli enzim aktiviteleri sıçan böbreği, Harderian bezi, fare dalağı, beyin dokusu, lenfositler, kültürdeki fibroblastlar ve daha birçok dokuda gösterilmiştir (

Keywords

karaciğer enzim doku

References

  • 1 - Barnes R ve ark : Ferrochelatase and delta-aminolaevtllate synthetase in brain, heart, kidney and liver of normal and porphyrie rats, Biochem J 124 : 633-641, 1971
  • 2.Badawy A, Evans M : The regulation of rat liver tryptophan pyrrolase by its cofactor haem, Biochem J 150 : 511-523, 1975
  • 3. Bonkowsky HL ve ark : The glucose effect in rat liver; Biochim Biophys Atta 230 561, 1973
  • 4.Colleran EM, Jones OT : Studies on the biosynthesis of cytochrome c, Biochem J 134 : 84, 1973
  • 5. Correia MA, Meer UA : Apocytoehrorn P 450 : Reconstitution and fonctional cytochrom with hemin in vitro, Proc Natl Acad Sci USA 72 : 400, 1975
  • 6 - De Matteis F, Sparks RG : iron dependent loss Of liver cytochrome P 450 haem in vivo and in vitro, FEES Mektup 29 141, 1973
  • 7.Doyle D, Schinlke RT : The genetic and developmental regulation of hepatic delta arni no levulinate dehydratase in mice, J Biol Chem 244 : 5449 - 1969
  • 8.Druyan R, Kelly A : The effect of exogenous delta arninatlaevulinate an rat liver haem and cytochromes, Biochem J 129 : 1095, 1972
  • 10 - Falk IF, Porra RJ ; The effects Of oxygen concentration Otl porphyrin biosynthesis chicken erytrocyte preparations, Biochem J 90 : 60, 69, 1964
  • 11. - Glass J, Lavidor M, Robinson SH Studies of murine erytroid cell developement, J cell Biol 63 zgg, 1965
  • 12 Granick S, Sass S : Delta-Amtnolacvulinic acid synthetase and control of heme and chlorophyll biosyntheses/ Metabolic Regulation kitabmdan, Ed. Vogel* s : 77, Academic Press, New York, 191 t
  • 13 - Granick S, Urata G Increase in activity Of delta aminolaevulinïc acid synthetase in liver mitochondria induced by feedinb of J Biol Chem 238 : 821-829, 1963
  • 14 - Granick S : The induction in Vitro Of the synthesis of delta-aminolaevulinic acid syntbetase in chemical porphyria, J Biol Chem 241 1359-1368, 1966
  • 15 Grayeel Al, Hörcher P, London 1M : The stimulation of globin synthesis by heme, Proc Natl Acad Sci USA 55 .9 560, 1966
  • 16 - Jacob ST, Scharf MB, Vessel ES : Role of RNA in induction of hepatic microsomal miked function oxidnses, Proc Natl Acad Sci USA 71 : 704. 1974
  • 17 Kurashima Y, Hayashi N, Kikuchi G ; Mechanism of inhibition by hemin of increase of delta-levnlinate synthetase in liver mitocondria, J Biochem 67 : 863, 1970
  • 18 - Kushner JP, Lef GR, Nacht S : The role of iron in the pathogenesis of polphyria cutanea tarda An in vitro model, I Invest 5t 3044, 1972 19 - Marver HS : The role of heme in the synthesis and repression of mierosop:lal protein, Microsomes and' drug Oxidations kitåbmdan, Edi JR Gillette, Academic Press, 1966
  • 20 Maxwell JD, Meyer UA : Effect of lead in hepatic delta-amino-levulinic acid synthetase activity in rats, Eur J Clin Invest 6 : 373, 1976
  • 21 - Meyer URS A. Schmid R ; The porphyrias, Genetic basis of metabolic disease bindan, chap : 50, Mc Graw Hill, New York, 1978
  • 22 - Mizoguchi H, Levere RD : Enhancement of heme and globin synthesis in cultured human marrow by certain 5 beta H steroid metabolites, J Exp Med 134 : 1501, 1971
  • 23 - Pinelli ve ark : Delta-Aminolevulinic acid synthetase induction, Biochem. Pharmacol 24 - Ponka P, Neuwirt J, Borova J The role of heme in the release of iron from transferrin in reticulocytes, Enzyme 17 91, 1973
  • 25 - Ptashne M Specific binding of the delta phage represor to delta DNA, Nature (Lond) 214 : 232, 1967
  • 26 - Remmer H ; The rele of liver in drug metabolism, Am J Med 49 : 617, 1970
  • 27 - Rose JA, Heliman ES, Tschüdy DP : Effect of diet on the induction of experimental porphyria, Metabolism 10 : 514, 1961
  • 28 Sinclair RP, Graniek S : Heme control of syntesis of delta-aminolevulinic acid synthetase in cultured chick ambryo liver Cells, Ann NY Acad Sci 244 : 509, 1975
  • 29 - Song CS ve ark : Influence of postnatal development on drug induced hepatic porphyria and the synthesis of cytochrome P 450y J Exp Med 134 : 1349, 1971 30 - Whítíng MS, Granick S : De(ta-AmínoIevuIinic acid synthetase from chick embryo liver mitochondria, J Biol Chem 251 • 1349, 1976
  • 31 Woods JS, Dixon RI : Studies of the perinatal differences in the activity Of hepatic Delta-Aminolevulinic acid synthetase, Biochem Pharmacol 21 1735, 1972
  • 32 - Vavra JD, Poff SA Heme and Þorphyrin synthesis in sideroblastic anernža, J Lab Clin Med 69 : 904, 1967
  • 33 - Zubay G, Schwartz D ; Mechanism of activation of catabolite sensitive genes, Quart Biol 35 ; 433, 1970

REGULATION OF HEME AND HEMOPROTEIN BIOSYNTHESIS IN THE LIVER

Year 1981, Volume: 34 Issue: 1, 177 - 183, 11.08.1981

Nihat Sipahi

Abstract

It has been shown that heme synthesis can occur outside of liver and erythrocytic cells, Various enzyme activities have been shown in rat kidney, Harderian gland, mouse spleen, brain tissue, lymphocytes, fibroblasts in culture and many other tissues

Keywords

erythrocytic activities lymphocytes

References

  • 1 - Barnes R ve ark : Ferrochelatase and delta-aminolaevtllate synthetase in brain, heart, kidney and liver of normal and porphyrie rats, Biochem J 124 : 633-641, 1971
  • 2.Badawy A, Evans M : The regulation of rat liver tryptophan pyrrolase by its cofactor haem, Biochem J 150 : 511-523, 1975
  • 3. Bonkowsky HL ve ark : The glucose effect in rat liver; Biochim Biophys Atta 230 561, 1973
  • 4.Colleran EM, Jones OT : Studies on the biosynthesis of cytochrome c, Biochem J 134 : 84, 1973
  • 5. Correia MA, Meer UA : Apocytoehrorn P 450 : Reconstitution and fonctional cytochrom with hemin in vitro, Proc Natl Acad Sci USA 72 : 400, 1975
  • 6 - De Matteis F, Sparks RG : iron dependent loss Of liver cytochrome P 450 haem in vivo and in vitro, FEES Mektup 29 141, 1973
  • 7.Doyle D, Schinlke RT : The genetic and developmental regulation of hepatic delta arni no levulinate dehydratase in mice, J Biol Chem 244 : 5449 - 1969
  • 8.Druyan R, Kelly A : The effect of exogenous delta arninatlaevulinate an rat liver haem and cytochromes, Biochem J 129 : 1095, 1972
  • 10 - Falk IF, Porra RJ ; The effects Of oxygen concentration Otl porphyrin biosynthesis chicken erytrocyte preparations, Biochem J 90 : 60, 69, 1964
  • 11. - Glass J, Lavidor M, Robinson SH Studies of murine erytroid cell developement, J cell Biol 63 zgg, 1965
  • 12 Granick S, Sass S : Delta-Amtnolacvulinic acid synthetase and control of heme and chlorophyll biosyntheses/ Metabolic Regulation kitabmdan, Ed. Vogel* s : 77, Academic Press, New York, 191 t
  • 13 - Granick S, Urata G Increase in activity Of delta aminolaevulinïc acid synthetase in liver mitochondria induced by feedinb of J Biol Chem 238 : 821-829, 1963
  • 14 - Granick S : The induction in Vitro Of the synthesis of delta-aminolaevulinic acid syntbetase in chemical porphyria, J Biol Chem 241 1359-1368, 1966
  • 15 Grayeel Al, Hörcher P, London 1M : The stimulation of globin synthesis by heme, Proc Natl Acad Sci USA 55 .9 560, 1966
  • 16 - Jacob ST, Scharf MB, Vessel ES : Role of RNA in induction of hepatic microsomal miked function oxidnses, Proc Natl Acad Sci USA 71 : 704. 1974
  • 17 Kurashima Y, Hayashi N, Kikuchi G ; Mechanism of inhibition by hemin of increase of delta-levnlinate synthetase in liver mitocondria, J Biochem 67 : 863, 1970
  • 18 - Kushner JP, Lef GR, Nacht S : The role of iron in the pathogenesis of polphyria cutanea tarda An in vitro model, I Invest 5t 3044, 1972 19 - Marver HS : The role of heme in the synthesis and repression of mierosop:lal protein, Microsomes and' drug Oxidations kitåbmdan, Edi JR Gillette, Academic Press, 1966
  • 20 Maxwell JD, Meyer UA : Effect of lead in hepatic delta-amino-levulinic acid synthetase activity in rats, Eur J Clin Invest 6 : 373, 1976
  • 21 - Meyer URS A. Schmid R ; The porphyrias, Genetic basis of metabolic disease bindan, chap : 50, Mc Graw Hill, New York, 1978
  • 22 - Mizoguchi H, Levere RD : Enhancement of heme and globin synthesis in cultured human marrow by certain 5 beta H steroid metabolites, J Exp Med 134 : 1501, 1971
  • 23 - Pinelli ve ark : Delta-Aminolevulinic acid synthetase induction, Biochem. Pharmacol 24 - Ponka P, Neuwirt J, Borova J The role of heme in the release of iron from transferrin in reticulocytes, Enzyme 17 91, 1973
  • 25 - Ptashne M Specific binding of the delta phage represor to delta DNA, Nature (Lond) 214 : 232, 1967
  • 26 - Remmer H ; The rele of liver in drug metabolism, Am J Med 49 : 617, 1970
  • 27 - Rose JA, Heliman ES, Tschüdy DP : Effect of diet on the induction of experimental porphyria, Metabolism 10 : 514, 1961
  • 28 Sinclair RP, Graniek S : Heme control of syntesis of delta-aminolevulinic acid synthetase in cultured chick ambryo liver Cells, Ann NY Acad Sci 244 : 509, 1975
  • 29 - Song CS ve ark : Influence of postnatal development on drug induced hepatic porphyria and the synthesis of cytochrome P 450y J Exp Med 134 : 1349, 1971 30 - Whítíng MS, Granick S : De(ta-AmínoIevuIinic acid synthetase from chick embryo liver mitochondria, J Biol Chem 251 • 1349, 1976
  • 31 Woods JS, Dixon RI : Studies of the perinatal differences in the activity Of hepatic Delta-Aminolevulinic acid synthetase, Biochem Pharmacol 21 1735, 1972
  • 32 - Vavra JD, Poff SA Heme and Þorphyrin synthesis in sideroblastic anernža, J Lab Clin Med 69 : 904, 1967
  • 33 - Zubay G, Schwartz D ; Mechanism of activation of catabolite sensitive genes, Quart Biol 35 ; 433, 1970
There are 29 citations in total.

Details

Primary Language Turkish
Subjects Gastroenterology and Hepatology
Journal Section Research Article
Authors

Nihat Sipahi This is me

Publication Date August 11, 1981
Published in Issue Year 1981 Volume: 34 Issue: 1

Cite

APA Sipahi, N. (1981). Karaciğerde Hem Ve Hemoprotein Biyosdntezinin Düzenlenmesi. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 34(1), 177-183. https://izlik.org/JA35JU36WC
AMA 1.Sipahi N. Karaciğerde Hem Ve Hemoprotein Biyosdntezinin Düzenlenmesi. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1981;34(1):177-183. https://izlik.org/JA35JU36WC
Chicago Sipahi, Nihat. 1981. “Karaciğerde Hem Ve Hemoprotein Biyosdntezinin Düzenlenmesi”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 34 (1): 177-83. https://izlik.org/JA35JU36WC.
EndNote Sipahi N (August 1, 1981) Karaciğerde Hem Ve Hemoprotein Biyosdntezinin Düzenlenmesi. Ankara Üniversitesi Tıp Fakültesi Mecmuası 34 1 177–183.
IEEE [1]N. Sipahi, “Karaciğerde Hem Ve Hemoprotein Biyosdntezinin Düzenlenmesi”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 34, no. 1, pp. 177–183, Aug. 1981, [Online]. Available: https://izlik.org/JA35JU36WC
ISNAD Sipahi, Nihat. “Karaciğerde Hem Ve Hemoprotein Biyosdntezinin Düzenlenmesi”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 34/1 (August 1, 1981): 177-183. https://izlik.org/JA35JU36WC.
JAMA 1.Sipahi N. Karaciğerde Hem Ve Hemoprotein Biyosdntezinin Düzenlenmesi. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1981;34:177–183.
MLA Sipahi, Nihat. “Karaciğerde Hem Ve Hemoprotein Biyosdntezinin Düzenlenmesi”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 34, no. 1, Aug. 1981, pp. 177-83, https://izlik.org/JA35JU36WC.
Vancouver 1.Sipahi N. Karaciğerde Hem Ve Hemoprotein Biyosdntezinin Düzenlenmesi. Ankara Üniversitesi Tıp Fakültesi Mecmuası [Internet]. 1981 Aug. 1;34(1):177-83. Available from: https://izlik.org/JA35JU36WC