Systematic Reviews and Meta Analysis
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Thymic Findings of Neural Tube Defects

Year 1989, Volume: 42 Issue: 2, 139 - 144, 02.07.1989

Fatma Nur Şeniz

https://izlik.org/JA34CY52EG

Abstract

Neural tube defects are the most common congenital anomalies. Organ system anomalies other than central nervous system aSSsOociated with neural tube defects are well known. Thymic changes have also been reported. This report presents the thymic findings of a prospectively series of 7 infants. Among these, 2 cases had normal thymus, 2 cases showed thymic enlargement, 2 cases showed small thymus, one case had double thymus. No previous case with neural tube defects showing small or double thymus or stippling in Hassall's corpuscles could be found in literature.

Keywords

neural tube defects anencephaly thymus

References

  • 1. Behçeci M, Çavdar A, Arcasoy A, Yavuz H, Bahçeci G : Fötal anomali görülen doğumlarda maternal serum çinko düzeyleri. 2. Çinko Simpozyumu ve XX. Ulusal Hematoloji Kongresi Özet Kitabı; s : Ankara, 1988.
  • 2. Chesnokova VM, Grutenko EV, Ivanova LN, and Ignatyeva EV : Evidence for thymus involvement in development of adrenal and gonadal endocrine İunctions in mice. Endocrinologica Experimentalis 21 : 133, 1987.
  • 3. ComsaJ, Leonhardt H, and Schwaz JA . Imfluence of the thymuş corticotropingrowth hormone interaction on the rejection of skin allografts in the rat. Ann NY Acad Sci 249 : 387, 1975.
  • 4. Çavdar AO, Babacan E, Aşık S, Arcasoy A, Ertem U, Himmetoğlu Ö, Bayçu T, and Akar N : Zinc levels of serum, plasma, erythrocytes ,and hair in Turkish women with anencephalic babies. In : Zinc Deficiency in Human Subjects (AS Prasad, AO Çavdar, GJ Brewer, and PJ Aggett, eds) Alan R Liss Inc, New York, PP, 207-210.
  • 5. Çavdar AO, Bahçeci M, Akar N, Erten J, Bahçeci G, Babacan E, Arcasoy A, and Yavuz H : Zinc status in pregnancy and tbe occurence of anencephaly in Turkey. J Trace Elem Elec Health Dis 2 ; 9, 1988.
  • 6. Deshaux P, and Rouabhia M : The thymus key organ between endocrinologic and immunologic systems, Ann NY Acad Sci 496 : 49, 1987.
  • 7. Fisenbarth GS, Shimizu K, Bowring MA, and Well 5 ; Expression of receptors for tetanus toxin and monoclonal antibody A2B5 by pancreatic cells. Proc Natl Acad Sci USA 79 : 5066, 1982.
  • 8. Gesnen V, Legras JJ, Eranchimont P, Baudrihaye M, Defresne P, and Boniver J: The neuroendocrine thymus : Coexistence of oxytocin and neurophysin in the human thymus. Science 232 : 508, 1986.
  • 9. Geenen V, Legras JJ, Franchimont P, Defrense P, Boniver J, Ivell R, and Richter D : The thymus as g neuroendocrine organ : Synhesis of vasopressin and oxytocin in human thymic epithelium. Ann NY Acad Sci 496 : 56, 1987.
  • 10. Giroud A . Anencephaly. In Vinken PJ, Bruyn GW, Myrianthopoulos NC (eds) : «Handbook of Cliniçal Neurology, Vol 30, Congönital Malformations of the Brain and Skull Part i» Amsterdam : Elsevier, PP 173-208, 1977.
  • 11. Haynes BF, Shimizu K, and Eisenbarth GS : Identification of human and rodent thymus endothelium using tetanus toxin and monoclonal antibody A2B5. J Clin Invest 71 : 9, 1983.
  • 12. Holmes LB, Driscoll SG, and Atkins L ; Etiologic heterogeneity of neurol tube defects. N Eng J Med 204 : 365, 1978.
  • 13. Le Douarin NM, and Jotercau FV ; Trgcing of cells of the avian thymus through embryonic life in interspecific chimeras. J Exp Med 142: 17, 1975.
  • 14. Lemire RJ, Beckwith JB, and Warkany J : Anencephaly, Raven Press, New York, 1978.
  • 15. Melnick M, and Myrianthopoulos NC : Studies in neural tube defects. Il. Pathologic findings in a prospectively collected series of anencephalics. Am Med Genet 26 : 797, 1987.
  • 16. Smith EM, and Blalock JE : Human Iymphocyte production of ACTH and endorphin-like substances : Association with leukocyte inferferon, Proc Natl Acad Sci USA 79 : 4226, 1981.
  • 17. Smith EM, Morrill AC, Meyer WJ, and Blalock JE , Corticotropin releasing factor induction of leukocyte-derived immunoreactive ACTH and endorphins. Nature 324 : 874, 1986.
  • 18. Yen $, and MacMahon B : Genelics of anencephaly and spina bifida. Lancet 2 : 623, 1968.

Nöral Tüp Defektlerinde Timus Bulguları

Year 1989, Volume: 42 Issue: 2, 139 - 144, 02.07.1989

Fatma Nur Şeniz

https://izlik.org/JA34CY52EG

Abstract

Nöral tüp defektleri, sık rastlanan konjenital anomalilerdendir. Nöral tüp defektlerinde, santral sinir sistemi anomalileriyle birlikte diğer organ anomalileri de bildirilmektedir. Timusa ait değişikliklerden de bahsedilmektedir. Bu yazıda, prospektif bir çalışmada Diyarbakır'da rastlanan 7 nöral tüp defektli bebeğin 2'sinde timus normal bulunduğu halde 2 vak'ada küçük timus, 2 vak'ada timus büyüklüğü, 1 vak'ada ise çift timus saptandı, Literatürde nöral tüp defekti vakalarında çift timus ile küçük timusa ve mikroskopik incelemede Haşssall cisimciklerinde görülen «stippling»e rastlanmamış olması nedeniyle vakalar ilginçtir.

Keywords

nöral tüp defekti anensefali timus

References

  • 1. Behçeci M, Çavdar A, Arcasoy A, Yavuz H, Bahçeci G : Fötal anomali görülen doğumlarda maternal serum çinko düzeyleri. 2. Çinko Simpozyumu ve XX. Ulusal Hematoloji Kongresi Özet Kitabı; s : Ankara, 1988.
  • 2. Chesnokova VM, Grutenko EV, Ivanova LN, and Ignatyeva EV : Evidence for thymus involvement in development of adrenal and gonadal endocrine İunctions in mice. Endocrinologica Experimentalis 21 : 133, 1987.
  • 3. ComsaJ, Leonhardt H, and Schwaz JA . Imfluence of the thymuş corticotropingrowth hormone interaction on the rejection of skin allografts in the rat. Ann NY Acad Sci 249 : 387, 1975.
  • 4. Çavdar AO, Babacan E, Aşık S, Arcasoy A, Ertem U, Himmetoğlu Ö, Bayçu T, and Akar N : Zinc levels of serum, plasma, erythrocytes ,and hair in Turkish women with anencephalic babies. In : Zinc Deficiency in Human Subjects (AS Prasad, AO Çavdar, GJ Brewer, and PJ Aggett, eds) Alan R Liss Inc, New York, PP, 207-210.
  • 5. Çavdar AO, Bahçeci M, Akar N, Erten J, Bahçeci G, Babacan E, Arcasoy A, and Yavuz H : Zinc status in pregnancy and tbe occurence of anencephaly in Turkey. J Trace Elem Elec Health Dis 2 ; 9, 1988.
  • 6. Deshaux P, and Rouabhia M : The thymus key organ between endocrinologic and immunologic systems, Ann NY Acad Sci 496 : 49, 1987.
  • 7. Fisenbarth GS, Shimizu K, Bowring MA, and Well 5 ; Expression of receptors for tetanus toxin and monoclonal antibody A2B5 by pancreatic cells. Proc Natl Acad Sci USA 79 : 5066, 1982.
  • 8. Gesnen V, Legras JJ, Eranchimont P, Baudrihaye M, Defresne P, and Boniver J: The neuroendocrine thymus : Coexistence of oxytocin and neurophysin in the human thymus. Science 232 : 508, 1986.
  • 9. Geenen V, Legras JJ, Franchimont P, Defrense P, Boniver J, Ivell R, and Richter D : The thymus as g neuroendocrine organ : Synhesis of vasopressin and oxytocin in human thymic epithelium. Ann NY Acad Sci 496 : 56, 1987.
  • 10. Giroud A . Anencephaly. In Vinken PJ, Bruyn GW, Myrianthopoulos NC (eds) : «Handbook of Cliniçal Neurology, Vol 30, Congönital Malformations of the Brain and Skull Part i» Amsterdam : Elsevier, PP 173-208, 1977.
  • 11. Haynes BF, Shimizu K, and Eisenbarth GS : Identification of human and rodent thymus endothelium using tetanus toxin and monoclonal antibody A2B5. J Clin Invest 71 : 9, 1983.
  • 12. Holmes LB, Driscoll SG, and Atkins L ; Etiologic heterogeneity of neurol tube defects. N Eng J Med 204 : 365, 1978.
  • 13. Le Douarin NM, and Jotercau FV ; Trgcing of cells of the avian thymus through embryonic life in interspecific chimeras. J Exp Med 142: 17, 1975.
  • 14. Lemire RJ, Beckwith JB, and Warkany J : Anencephaly, Raven Press, New York, 1978.
  • 15. Melnick M, and Myrianthopoulos NC : Studies in neural tube defects. Il. Pathologic findings in a prospectively collected series of anencephalics. Am Med Genet 26 : 797, 1987.
  • 16. Smith EM, and Blalock JE : Human Iymphocyte production of ACTH and endorphin-like substances : Association with leukocyte inferferon, Proc Natl Acad Sci USA 79 : 4226, 1981.
  • 17. Smith EM, Morrill AC, Meyer WJ, and Blalock JE , Corticotropin releasing factor induction of leukocyte-derived immunoreactive ACTH and endorphins. Nature 324 : 874, 1986.
  • 18. Yen $, and MacMahon B : Genelics of anencephaly and spina bifida. Lancet 2 : 623, 1968.
There are 18 citations in total.

Details

Primary Language English
Subjects Pediatric Surgery
Journal Section Systematic Reviews and Meta Analysis
Authors

Fatma Nur Şeniz This is me

Publication Date July 2, 1989
IZ https://izlik.org/JA34CY52EG
Published in Issue Year 1989 Volume: 42 Issue: 2

Cite

APA Şeniz, F. N. (1989). Thymic Findings of Neural Tube Defects. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 42(2), 139-144. https://izlik.org/JA34CY52EG
AMA 1.Şeniz FN. Thymic Findings of Neural Tube Defects. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1989;42(2):139-144. https://izlik.org/JA34CY52EG
Chicago Şeniz, Fatma Nur. 1989. “Thymic Findings of Neural Tube Defects”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 42 (2): 139-44. https://izlik.org/JA34CY52EG.
EndNote Şeniz FN (July 1, 1989) Thymic Findings of Neural Tube Defects. Ankara Üniversitesi Tıp Fakültesi Mecmuası 42 2 139–144.
IEEE [1]F. N. Şeniz, “Thymic Findings of Neural Tube Defects”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 42, no. 2, pp. 139–144, July 1989, [Online]. Available: https://izlik.org/JA34CY52EG
ISNAD Şeniz, Fatma Nur. “Thymic Findings of Neural Tube Defects”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 42/2 (July 1, 1989): 139-144. https://izlik.org/JA34CY52EG.
JAMA 1.Şeniz FN. Thymic Findings of Neural Tube Defects. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1989;42:139–144.
MLA Şeniz, Fatma Nur. “Thymic Findings of Neural Tube Defects”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 42, no. 2, July 1989, pp. 139-44, https://izlik.org/JA34CY52EG.
Vancouver 1.Şeniz FN. Thymic Findings of Neural Tube Defects. Ankara Üniversitesi Tıp Fakültesi Mecmuası [Internet]. 1989 July 1;42(2):139-44. Available from: https://izlik.org/JA34CY52EG