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Acute Myocardial Glucagon Effect on Free Fatty Acids

Year 1978, Volume: 31 Issue: 3 , 577 - 584 , 30.09.1978
https://izlik.org/JA28FG39HN

Abstract

1. Bu çalışmada 10 normal ve 22 akut myokard infarktüslü hastaya, 1 mgr.
İ.V. glukagon verilerek, glukagon'un serbest yağ asitleri üzerine etkisi araştırılmıştır.
2. Glukagon'un lipolitik etkisi akut myokard infarktüslü hastalarda normal şahıslardan farklı olarak belirgin şekilde artmaktadır (p<0,01).
3. Akut myokard infarktüslü hastalarda glukagon verildikten sonra tesbit edilen serbest yağ asitleri değerlerindeki yükselme derecesi ile aritmi oluşumu
arasındaki ilgi incelenmiştir.
4, Akut myokard infarktüslü hastalarda plâzma serbest yağ asitleri yüksekliği
ile aritmi teşekkülü arasında hiç bir ilgi olmadığı saptanmıştır. U

Ethical Statement

-

Supporting Institution

-

Project Number

-

Thanks

-

References

  • 1. Harrison's Principles of İnternal Medicine 560, 1974.
  • 2. Williams, J.F., Childress R.H., Chhig J.N., Border J.F : Hemodiynamic effect of glucagon in patients with heart dicasse. Circulation 39 : 38, 1969.
  • 3. armley W.W., Sonnenblick E.H. Glucagon : A new agent in cardiac therapy. Am, J. Cardiol, 27 : 298, 1971.
  • 4. Vander Ark CR,, Reynolds EW. : Ctinical evaluation of glucagon by continous infu- sion in the treatmend of low cardiaz cutput states. Am. Heart. J, 79 : 481, 1970,
  • 5. Deraney MER. : Glucagon. One answer to cardiogenic shock. Am. J, Med Sci, 261 : 149, 1971.
  • 6. PozzaG.,etal: Lipolytic effect of intra - arterial injection of glucagon in man. Horm. Metab. Res, 3 : 291, 1971,
  • 7. Liljenquist J., Bombay .D. et al : Effects of gllucagon on lipolysis and ketogenesis in normal and diabetic men, J. Clin. invest. 53/1 : 190, 1974;
  • 8. Hagen J.H. : The effect of insülin on concentration of plasma giycerol, 1. Lipid.- Res. 4: 46, 1963, ii
  • 9. Gupta P.R., M.B,, Sinha M.K. et al : Insülin, free fatty acids, and glucose TeSponse to intravenous glucagon following imyocardia! infarction, Circulation, 49 ; 357, 1974. :
  • 10. Gupta D.K,, Young R,, İewitt DE 'Hertog M. : İncreased plasme free fatty acids concentration and their significance ir patients with acute myocardial infarction. Lan- * cet 2 ; 1209, 1969,
  • 11. Oliver MF, Kurien V.A., Greenwod TW, : Relation between serum free - fatty - acids and arrhythmias and. death after acufe myocasdial infarction. Lancet 1: 710, 1968,
  • 12. Dole VP.: A relation betwen non - esterified 'fatty acids in plazma and the metabolism-of glucose, J. Clin. İnvest 35 : 150, 1956,
  • 13. Whitty AJ, Shima K., Trubow M., and Foa P.P. : effect of glucagen and of insülin on serum İree fatty acids in. nofmal and depancreatized dogs. Proc. Soc. Exp. Biol. Med. 130 ; 55, 1969,
  • 14. Rutenberg H.L., Pamintuan 1.C, Solit LA, : Serum - free - fatty - acids and their re- Jation to complications after acute myocardial infarction, Lancet : Septmeber 13 : 559, 1969,
  • 15. Dhingra R.C., Khan A. etal. : Effect of glucagon on cardiaç conduction in man, Am. I. Cardiol, 33 : 509, 1974.

Akut Myokard Glukagon'un Serbest Yağ Asitlerine Etkisi

Year 1978, Volume: 31 Issue: 3 , 577 - 584 , 30.09.1978
https://izlik.org/JA28FG39HN

Abstract

1. In this study 10 normal, 22 patients with acute myocardial infarction Were
given İ.V. glucagon; 1 mgr. to each and the effect of it on free fatty acids
was studiçd. i
2. Lipolytic effect of glücagon in the patients with acute myocardial infarçtion
“is much more stronger than normal persons (p<0,01)
3. In such cases of myocardial infarction, after the injection of glucagon, the
relation between increased free tatty acidy acids level and arrhythmias pro-
.duction is studied. . i
4. In the same case again, there is no relation between the level of free fatty
acids and the production of arrhythmias.

Ethical Statement

-

Supporting Institution

-

Project Number

-

Thanks

-

References

  • 1. Harrison's Principles of İnternal Medicine 560, 1974.
  • 2. Williams, J.F., Childress R.H., Chhig J.N., Border J.F : Hemodiynamic effect of glucagon in patients with heart dicasse. Circulation 39 : 38, 1969.
  • 3. armley W.W., Sonnenblick E.H. Glucagon : A new agent in cardiac therapy. Am, J. Cardiol, 27 : 298, 1971.
  • 4. Vander Ark CR,, Reynolds EW. : Ctinical evaluation of glucagon by continous infu- sion in the treatmend of low cardiaz cutput states. Am. Heart. J, 79 : 481, 1970,
  • 5. Deraney MER. : Glucagon. One answer to cardiogenic shock. Am. J, Med Sci, 261 : 149, 1971.
  • 6. PozzaG.,etal: Lipolytic effect of intra - arterial injection of glucagon in man. Horm. Metab. Res, 3 : 291, 1971,
  • 7. Liljenquist J., Bombay .D. et al : Effects of gllucagon on lipolysis and ketogenesis in normal and diabetic men, J. Clin. invest. 53/1 : 190, 1974;
  • 8. Hagen J.H. : The effect of insülin on concentration of plasma giycerol, 1. Lipid.- Res. 4: 46, 1963, ii
  • 9. Gupta P.R., M.B,, Sinha M.K. et al : Insülin, free fatty acids, and glucose TeSponse to intravenous glucagon following imyocardia! infarction, Circulation, 49 ; 357, 1974. :
  • 10. Gupta D.K,, Young R,, İewitt DE 'Hertog M. : İncreased plasme free fatty acids concentration and their significance ir patients with acute myocardial infarction. Lan- * cet 2 ; 1209, 1969,
  • 11. Oliver MF, Kurien V.A., Greenwod TW, : Relation between serum free - fatty - acids and arrhythmias and. death after acufe myocasdial infarction. Lancet 1: 710, 1968,
  • 12. Dole VP.: A relation betwen non - esterified 'fatty acids in plazma and the metabolism-of glucose, J. Clin. İnvest 35 : 150, 1956,
  • 13. Whitty AJ, Shima K., Trubow M., and Foa P.P. : effect of glucagen and of insülin on serum İree fatty acids in. nofmal and depancreatized dogs. Proc. Soc. Exp. Biol. Med. 130 ; 55, 1969,
  • 14. Rutenberg H.L., Pamintuan 1.C, Solit LA, : Serum - free - fatty - acids and their re- Jation to complications after acute myocardial infarction, Lancet : Septmeber 13 : 559, 1969,
  • 15. Dhingra R.C., Khan A. etal. : Effect of glucagon on cardiaç conduction in man, Am. I. Cardiol, 33 : 509, 1974.
There are 15 citations in total.

Details

Primary Language Turkish
Subjects Cardiology
Journal Section Research Article
Authors

Vesile Kolaç This is me

Project Number -
Publication Date September 30, 1978
IZ https://izlik.org/JA28FG39HN
Published in Issue Year 1978 Volume: 31 Issue: 3

Cite

APA Kolaç, V. (1978). Acute Myocardial Glucagon Effect on Free Fatty Acids. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 31(3), 577-584. https://izlik.org/JA28FG39HN
AMA 1.Kolaç V. Acute Myocardial Glucagon Effect on Free Fatty Acids. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1978;31(3):577-584. https://izlik.org/JA28FG39HN
Chicago Kolaç, Vesile. 1978. “Acute Myocardial Glucagon Effect on Free Fatty Acids”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 31 (3): 577-84. https://izlik.org/JA28FG39HN.
EndNote Kolaç V (September 1, 1978) Acute Myocardial Glucagon Effect on Free Fatty Acids. Ankara Üniversitesi Tıp Fakültesi Mecmuası 31 3 577–584.
IEEE [1]V. Kolaç, “Acute Myocardial Glucagon Effect on Free Fatty Acids”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 31, no. 3, pp. 577–584, Sept. 1978, [Online]. Available: https://izlik.org/JA28FG39HN
ISNAD Kolaç, Vesile. “Acute Myocardial Glucagon Effect on Free Fatty Acids”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 31/3 (September 1, 1978): 577-584. https://izlik.org/JA28FG39HN.
JAMA 1.Kolaç V. Acute Myocardial Glucagon Effect on Free Fatty Acids. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1978;31:577–584.
MLA Kolaç, Vesile. “Acute Myocardial Glucagon Effect on Free Fatty Acids”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 31, no. 3, Sept. 1978, pp. 577-84, https://izlik.org/JA28FG39HN.
Vancouver 1.Vesile Kolaç. Acute Myocardial Glucagon Effect on Free Fatty Acids. Ankara Üniversitesi Tıp Fakültesi Mecmuası [Internet]. 1978 Sep. 1;31(3):577-84. Available from: https://izlik.org/JA28FG39HN