Research Article
BibTex RIS Cite

Ekzojen Obezitede Uzun Zincirli Yağ Asitlerinin İnsülin Dinamiğine Etkileri

Year 1974, Volume: 27 Issue: 1-2, 81 - 90, 30.06.1974
https://izlik.org/JA84TF58UH

Abstract

Bu çalısmada diyabetik olmayan 11 obez kisiye, oral yolla, 35 g. uzun zincirli asitlerinden rnütesekkil trigliserid verilmistir.
Ça11srnaya dahil edilen vakaların plazma IRI seviyeleri, kan sekerleri, serbest yag asit ve trigliseridleri 3,5 saat süre ile takip edilmis, yag verilmesinden 3 saat sonra, plazma IRI seviyesinde istatistik oltarak anlamll bir artis husule geldiäi saptanrmstlr.
Bu husus obez ve diyabetik olmayan sahlslara klsa ve uzun zincirli yağ asitleri yükleme ile ilgili önceki çallsmarımızla klyaslanmıstlr.

References

  • 1 — Oakley, W. Ct., Pyke, D. A. , Taylor, K. W. : Clinical Diabetes and its Biochemical Basis P. 15, 1968. Alden and Mowbray Ltd. Oxford.
  • 2 — Zimmerman, H. Z., and West, M. : Serum enzymes in Gastrointestinal disease. The Med. Clin, of North. Am. 48:189, 1964. 90
  • 3 Tuerkischer, E. Wertheimer, E. : Glycogen and adipose tissue. J. Physiol., Lond. 100, 385. 4 Karam, J. H. , Grodsky, G. M. and Forsham, P. H. : Excessive instilin response to glucose in obese subjects as measured by immunuchemical assay. Diabetes. 12, 197, 66, 1963.
  • 5 — Yalow R. S., Glick, S. M., Roth, J. and Berson, S. A. : Plasma insulin and growth hormone levels in obesity and diabetes. Ann, N. Y. Acad. Sci. 131, 357, 1965.
  • 6 Erdogan, G. : Normal sahlslarda uzun ve klsa zincirli yag asitlerinin immunoreaktif insulin dinamižine etkileri. A. tj. TIP Fak. Mec. 26/6, 1973.
  • 7 — Arquilla, E. D. and Stavistky, A. B. : The production and identification of antibodies to insulin and their use in assaying insulin. J. Clin. Ínvest. 35:3585 1956,
  • 8 — Yelow, R. S. and Berson, S. Immunoassay of endogenous plasma insulin in man. J. Clin. Invest. 39:1157, 1960.
  • 9 — Hales, C. N. and Randi, P. J. : Double Antibody Method. Lancet, 1:200, 1963. 10 — The Radio Chemical Centre. Amersham. Tecnical Bulletein 68/6.
  • 11 — Dole, V. P. : Determination of triglycerides in plasma. J. Clin. Invest. 35:150, 1956.
  • 12 — Van Hardel, E. X., Silversmit, D. B. : Micromethod for the determination of serum triglycerides. J. of Lab. Clin. and Med. 50/1-6, 152, 1957.
  • 13 — Salons, B. L. , Vise, J. : Metabolic Studies of Human obesity. The med. Clin. of North. Am. 5•.533, 1970.
  • 14 — Berson, S. A. and Yalow : Some Curent Contraversies jn diabetes reseach. Diabetes. 14:549, 1965.
  • 15 — Steiner, D. F., Hallund, O., A., Cho, S. and Bayless, C. : Isolation and properties of proinsulin interm,ediate form crystalline bovine insulin. Diabetes. 17:725, 1968.
  • 16 Salons, L. B. , Knitle J. L. and Hirsch, J. : The role of adipose tissue insulin sensivity in the carbonhydrate in tolerance of human obesity. J. Clin. Invest. 47:153, 1968.

Effects Of Long Chain ​​Fatty Acids On Insulin Dynamics In Extragenogenic Obesity

Year 1974, Volume: 27 Issue: 1-2, 81 - 90, 30.06.1974
https://izlik.org/JA84TF58UH

Abstract

In this study, 11 non-diabetic obese individuals were orally administered 35 g of long-chain fatty acid-derived triglycerides.

The plasma IRI levels, blood sugars, free fatty acids and triglycerides of the cases included in the study were monitored for 3.5 hours, and it was determined that there was a statistically significant increase in plasma IRI levels 3 hours after fat administration.

This issue was compared with our previous studies on loading short and long-chain fatty acids to obese and non-diabetic individuals.

References

  • 1 — Oakley, W. Ct., Pyke, D. A. , Taylor, K. W. : Clinical Diabetes and its Biochemical Basis P. 15, 1968. Alden and Mowbray Ltd. Oxford.
  • 2 — Zimmerman, H. Z., and West, M. : Serum enzymes in Gastrointestinal disease. The Med. Clin, of North. Am. 48:189, 1964. 90
  • 3 Tuerkischer, E. Wertheimer, E. : Glycogen and adipose tissue. J. Physiol., Lond. 100, 385. 4 Karam, J. H. , Grodsky, G. M. and Forsham, P. H. : Excessive instilin response to glucose in obese subjects as measured by immunuchemical assay. Diabetes. 12, 197, 66, 1963.
  • 5 — Yalow R. S., Glick, S. M., Roth, J. and Berson, S. A. : Plasma insulin and growth hormone levels in obesity and diabetes. Ann, N. Y. Acad. Sci. 131, 357, 1965.
  • 6 Erdogan, G. : Normal sahlslarda uzun ve klsa zincirli yag asitlerinin immunoreaktif insulin dinamižine etkileri. A. tj. TIP Fak. Mec. 26/6, 1973.
  • 7 — Arquilla, E. D. and Stavistky, A. B. : The production and identification of antibodies to insulin and their use in assaying insulin. J. Clin. Ínvest. 35:3585 1956,
  • 8 — Yelow, R. S. and Berson, S. Immunoassay of endogenous plasma insulin in man. J. Clin. Invest. 39:1157, 1960.
  • 9 — Hales, C. N. and Randi, P. J. : Double Antibody Method. Lancet, 1:200, 1963. 10 — The Radio Chemical Centre. Amersham. Tecnical Bulletein 68/6.
  • 11 — Dole, V. P. : Determination of triglycerides in plasma. J. Clin. Invest. 35:150, 1956.
  • 12 — Van Hardel, E. X., Silversmit, D. B. : Micromethod for the determination of serum triglycerides. J. of Lab. Clin. and Med. 50/1-6, 152, 1957.
  • 13 — Salons, B. L. , Vise, J. : Metabolic Studies of Human obesity. The med. Clin. of North. Am. 5•.533, 1970.
  • 14 — Berson, S. A. and Yalow : Some Curent Contraversies jn diabetes reseach. Diabetes. 14:549, 1965.
  • 15 — Steiner, D. F., Hallund, O., A., Cho, S. and Bayless, C. : Isolation and properties of proinsulin interm,ediate form crystalline bovine insulin. Diabetes. 17:725, 1968.
  • 16 Salons, L. B. , Knitle J. L. and Hirsch, J. : The role of adipose tissue insulin sensivity in the carbonhydrate in tolerance of human obesity. J. Clin. Invest. 47:153, 1968.
There are 14 citations in total.

Details

Primary Language Turkish
Subjects Endocrinology
Journal Section Research Article
Authors

Gürbüz Erdoğan This is me

Publication Date June 30, 1974
IZ https://izlik.org/JA84TF58UH
Published in Issue Year 1974 Volume: 27 Issue: 1-2

Cite

APA Erdoğan, G. (1974). Ekzojen Obezitede Uzun Zincirli Yağ Asitlerinin İnsülin Dinamiğine Etkileri. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 27(1-2), 81-90. https://izlik.org/JA84TF58UH
AMA 1.Erdoğan G. Ekzojen Obezitede Uzun Zincirli Yağ Asitlerinin İnsülin Dinamiğine Etkileri. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1974;27(1-2):81-90. https://izlik.org/JA84TF58UH
Chicago Erdoğan, Gürbüz. 1974. “Ekzojen Obezitede Uzun Zincirli Yağ Asitlerinin İnsülin Dinamiğine Etkileri”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 27 (1-2): 81-90. https://izlik.org/JA84TF58UH.
EndNote Erdoğan G (June 1, 1974) Ekzojen Obezitede Uzun Zincirli Yağ Asitlerinin İnsülin Dinamiğine Etkileri. Ankara Üniversitesi Tıp Fakültesi Mecmuası 27 1-2 81–90.
IEEE [1]G. Erdoğan, “Ekzojen Obezitede Uzun Zincirli Yağ Asitlerinin İnsülin Dinamiğine Etkileri”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 27, no. 1-2, pp. 81–90, June 1974, [Online]. Available: https://izlik.org/JA84TF58UH
ISNAD Erdoğan, Gürbüz. “Ekzojen Obezitede Uzun Zincirli Yağ Asitlerinin İnsülin Dinamiğine Etkileri”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 27/1-2 (June 1, 1974): 81-90. https://izlik.org/JA84TF58UH.
JAMA 1.Erdoğan G. Ekzojen Obezitede Uzun Zincirli Yağ Asitlerinin İnsülin Dinamiğine Etkileri. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1974;27:81–90.
MLA Erdoğan, Gürbüz. “Ekzojen Obezitede Uzun Zincirli Yağ Asitlerinin İnsülin Dinamiğine Etkileri”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 27, no. 1-2, June 1974, pp. 81-90, https://izlik.org/JA84TF58UH.
Vancouver 1.Gürbüz Erdoğan. Ekzojen Obezitede Uzun Zincirli Yağ Asitlerinin İnsülin Dinamiğine Etkileri. Ankara Üniversitesi Tıp Fakültesi Mecmuası [Internet]. 1974 Jun. 1;27(1-2):81-90. Available from: https://izlik.org/JA84TF58UH