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Clinical, microscopic and electronmicroscopic Study of Systemic Lupus Erythematosus

Year 1974, Volume: 27 Issue: 1-2, 371 - 388, 30.06.1974
https://izlik.org/JA35CZ42RD

Abstract

12 year old boy having high fever, arthralgy and edema was hospitalized and systemic lupus erythematosus nephritis was diagnosed after observing the symptoms of albuminuri, hematuri slendruri and high blood urea content. LE cells were seen .q.t the peripheral Biopsy material from the kidney was examined to observe the microscopic and electronmicroscopic findings.

Supporting Institution

Ankara University Faculty of Medicine

References

  • 1 — Baehr, G. , Klemperer P. and Schifrin A. : A diffuse disease of the peripheral circulation (usually associated with lupus erythematosus and endocarditis) Tr. A. Am. Physicians. 50: 139, 1935.
  • 2 Banks, B. M. : Is there a common. deneminator in scleroderma, dermatomyositis, disseminated lupus erythematosus, the Libman - Sacks Syndrome and polyarteritis nodosa? New England J. Med. 225:433, 1941.
  • 3 — Barber, H. W. : Lupus erythematosus associated with streptococcal in v fection of the fonsil. Brit. J. Dermat. 31: 186, 1919.
  • 4 — Biett, T. : Written in : Abrege pratique des maladies de la peau by Casenave A. and Schedel H, E. Paržs, 1828.
  • 5 Cruz, R. A. , Harneker, J. , Ducach, G. , Jalil, J. and Gonzalez, F. : Clinical diagnosis of systemic lupus erythematosus. Am. J. Med. 25:409, 1958.
  • 6 Dixon, F. J. , Feldman, J. D. and Vazquez, J. J. : Experimental glomerulonephritis. The pathogenesis of a Laboratory model resembling the spectrum of human glomerulonephritis. J. Med. 113 :899, 1961.
  • 7 Dubois, E. L. and Tuffanelli, D. L, : Clinical manifestations of Systemic lupus erytematosus. JAMA 190: 104, 1964.
  • 8 Ehrich, W. E. : Nature of the collagen diseases. Amt Heart. J t 43: 121, 1952.
  • 9 Fisher, G. S. and Moyer, J. B. : Hematologic phenomena as a test for acute disseminated lupus erythematosus. Hosp. Bull. Detroid. 28:3, 1950. 10 Gold, S. C. and Cowing, N. F. : Systemic lupus erythematosus. A clinical and pathological study. Quart J. Med. 22:45? , 1953.
  • 11 • Grausz, H., Barley, L. E., Stephens, B. G., Lee, J. C., Hopper, J. : Diagnostic import of virus li.ke particles in the glomerular endothelium of patients with systemic lupus erythematosus New Fang. J. Med. 283:506, 1970.
  • 12 Györkey, F. , Min, K. W. , Sincovics, J. G, : Systemic lupus erythematosus and myxo - virus New, Eng. J. Med. 280:333, 1969.
  • 13 — Hargraves, M. M. , Richmond, H. and Morton, R. : Presentation of two bone - marrow elements. (The tart» cell and cell. Proc. Staff. Meet. Myo Clin. 23:25, 1948.
  • 14 — Harvey, M., Shulman, L. E., Tumulty, P. A., Conley, C. and Schoenrich, E. H. : Systemic lupus erythematosus : Review of the literature and clinical analysis of 138 cases. Medicine 33:291, 1954,
  • 15 Jessar, R. A. , Havers, L. W. and Rogan, C. : Matural history of lupus erythematosus disseminatus. Ann. Int. Med. 38: 717, 1953.
  • 16 Kapcsi, M. K. : Neue Beiträge zur Kenntniss des lupus erythematosus Arch. F. Dermat. syph. 4:36, 1872. 17 — Kawano, K., Miller, L. and Kimmelstiel, P. : Virus - like structures in lupus erythematosus. New Eng. J. Med. 281:1228, 1969.
  • 18 Keil, H. : Relationship between lupus erythematosus and tuberculosis A critical review based on observation at necropcy. Arch. Dermat. and syph. 28:765, 1933.
  • 19 Keith, N. M. and Rowntree, L. G. : A study of renal complications of disseminated lupus erythematosus. Report of four cases. Tr. A. Am. Phys. 37•.487, 1922.
  • 20 — Kelvin, J. : Lupus erythematosus and tuberculin test. Lancet 5:59'7, 1941.
  • 21 — Klemperer, P., Pollack, A. D. and Baehr, G. : On the nature of acute lupus erythematosus. New York State J. Med. 42:2225, 1942.
  • 22 — Klinge, F. : Der Rheumatismus; pathologisch - anatomische und experi• mentell pathologische tatsachen und ihre auswertung fur das arztliche Rheumaproblem. Ergeben D. Allg. U. Path. Anat. 27:1, 1933.
  • 23 — Koets, P. Excretion of urinary 17 - ketosteroids in chronic lupus erythematosus case report. Stanford M. Bull. 9:256, 1951.
  • 24 — Koffler, D, Schur, P. He, Kunkel, H. G. : Immunological studies concerning the nephritis of systemic lupus erythematosus. J. exper. Med. 1967.
  • 25 — Kong, T., Kelum, R. and Haserick, HI : Clinical diagnosis of cardiac involvement in systemic lupus erythematosus. A correlation of clinical and autopsy findings in thirty patients. Circulation 26:7, 1962.
  • 26 — Kren, O. : Zur Kolarung der Pathogenese des lupus Erythematodes acutus. Wien Med. Wchnschr. 86:680, 1936.
  • 27 -— Kunkel, H. R. : Mechanism of renal infury in systemic lupus erythematosus. Arthritis and Rheumatism. 9:725, 1966.
  • 28 — Lee, S. L. : A simple test for L. cell. Am. J. Clin. Path. 21:492, 1951. 29 — Moolten, S. E. and Clark, E. : Viremia in acute hemolytic anemia and in autohemagglutination. Arch. Int. Med. 89:27Ù, 1952.
  • 30 Muehrcke, R. C., Kark, R. M., Pirani, C. L. and Pollack, V. F,. : Lupus nephritisi A Clinical and Pathologic Study based on renal biopsies. Medicine 36:1, 1957. 31 Norton, W. L. : Endothelial inclusions in active lesions in systemic lupus erythematosus. The Lab. and Clin. Med. 74:369, 1969.
  • 32 — Norton, W. Ia., Hurd, E. R., Lewis, D. C. and Ziff, M. : Evidence of microvascular injury in scleroderma and systemic lupus erythematosus; quantitative study of the microvascular bed. The J, Lab, and Olin. Med. 71:919, 1968.
  • 33 — Ormsby, O. S. and Montgomery, H. : Disease of the skin. Ed. 7. Philadelphia, 1948.
  • 34 — Osler, W. : On the visceral complications of erythema exudativum multiforme. Am. J. Med. sc. 110:629, 1895.
  • 35 — Parelhoff, M. E. : Demostration of the LE cell phenomenon in Subacute glomerulonephritis. Sinai Hosp. Bull. 2:12, 1953.
  • 36 — Pincus, T. , Blacklow, N. R. , Grimley, P. M. , Bellanti, J. A. : Glomerular microtubules of systemic lupus erythem.atosus. The Lancet 2: 1058, 1970.
  • 37 — Rayer, P. : Traite théorique et pratique des maladies de la peau. Fondé sur de nouvelles Recherches d' Anatomie et de physiologie pathologiques, Paris, J-B-Bai11iere, 1826.
  • 38 — Rich, A. R. and Gregory, J. E. : Experimental anaphylactic lesions of the coronary arteries of the sclerotic type commonly associated with Rheumatic fever and disseminated lupus erythematosus. Bull. Johns. Hopkins Hosp. 87:549, 1950.
  • 39 — Rose, E. and Pielsbury, D. M. : Acute disseminated lupus erythematosus, systemic disease. Ann. Int. Med. 12:951, 1939.
  • Schur, P. H. and Sandson, J, : Immunologic factors and clinical actiVity in systemic lupus erythematosus. New Eng. J. Med. 278:533, 1968. Shearn, M. A and Pirofsky, B. : Disseminated lupus erythematosus. Arch. Int. Med. 90:790, 1952.
  • Stokes, J. H. , Beerman, H. and Ingraham, N. R. : The lupus arythematosus, concept and attempt at integration. Am. J. Med. Sc. 207 :540, 1944.
  • 43 Tan, E. M. and KunluA H. G. : An immunofluorescent study of the skin lesions in systemic lupus erythematosus Arthritis and Rheumatism. 9:37, 1966.
  • 44 Walsh, J. and Egan, R. : The reliability of L. E. test. New Eng. J. Med. 246:775, 1952.
  • 45 — Welsh, A. L. . Specificity of Streptococci isolated from patients with skin diseases. Studies on pemphigus, dermatitis herpetiformis, lupus erythematosus and erythema multiforme J. Invest. Dermat. 10:305, 1948.

Sistemik Lupus Eritematosis'in Klinik Mikroskopik Ve Elektron Mikroskopik İncelenmesi

Year 1974, Volume: 27 Issue: 1-2, 371 - 388, 30.06.1974
https://izlik.org/JA35CZ42RD

Abstract

Yüksek ateş, artralji ve ödem şikâyeti ile kliniğimize yatırılan 12 yaşındaki bir erkek çocuğunda, albuminuri, hematuri, slendruri ve yüksek kan üre seviyesi tespit edilerek lupus nefriti düşünülmüştür. Periferik kandan hazırlanan preparatta LE hücreleri görülmüştür. Böbrekte husule gelen değişiklikleri görmek için, iğne biopsisi ile alınan materyel mikroskopik ve elektron mikroskopik olarak incelenmiştir.

Supporting Institution

Ankara University Faculty of Medicine

References

  • 1 — Baehr, G. , Klemperer P. and Schifrin A. : A diffuse disease of the peripheral circulation (usually associated with lupus erythematosus and endocarditis) Tr. A. Am. Physicians. 50: 139, 1935.
  • 2 Banks, B. M. : Is there a common. deneminator in scleroderma, dermatomyositis, disseminated lupus erythematosus, the Libman - Sacks Syndrome and polyarteritis nodosa? New England J. Med. 225:433, 1941.
  • 3 — Barber, H. W. : Lupus erythematosus associated with streptococcal in v fection of the fonsil. Brit. J. Dermat. 31: 186, 1919.
  • 4 — Biett, T. : Written in : Abrege pratique des maladies de la peau by Casenave A. and Schedel H, E. Paržs, 1828.
  • 5 Cruz, R. A. , Harneker, J. , Ducach, G. , Jalil, J. and Gonzalez, F. : Clinical diagnosis of systemic lupus erythematosus. Am. J. Med. 25:409, 1958.
  • 6 Dixon, F. J. , Feldman, J. D. and Vazquez, J. J. : Experimental glomerulonephritis. The pathogenesis of a Laboratory model resembling the spectrum of human glomerulonephritis. J. Med. 113 :899, 1961.
  • 7 Dubois, E. L. and Tuffanelli, D. L, : Clinical manifestations of Systemic lupus erytematosus. JAMA 190: 104, 1964.
  • 8 Ehrich, W. E. : Nature of the collagen diseases. Amt Heart. J t 43: 121, 1952.
  • 9 Fisher, G. S. and Moyer, J. B. : Hematologic phenomena as a test for acute disseminated lupus erythematosus. Hosp. Bull. Detroid. 28:3, 1950. 10 Gold, S. C. and Cowing, N. F. : Systemic lupus erythematosus. A clinical and pathological study. Quart J. Med. 22:45? , 1953.
  • 11 • Grausz, H., Barley, L. E., Stephens, B. G., Lee, J. C., Hopper, J. : Diagnostic import of virus li.ke particles in the glomerular endothelium of patients with systemic lupus erythematosus New Fang. J. Med. 283:506, 1970.
  • 12 Györkey, F. , Min, K. W. , Sincovics, J. G, : Systemic lupus erythematosus and myxo - virus New, Eng. J. Med. 280:333, 1969.
  • 13 — Hargraves, M. M. , Richmond, H. and Morton, R. : Presentation of two bone - marrow elements. (The tart» cell and cell. Proc. Staff. Meet. Myo Clin. 23:25, 1948.
  • 14 — Harvey, M., Shulman, L. E., Tumulty, P. A., Conley, C. and Schoenrich, E. H. : Systemic lupus erythematosus : Review of the literature and clinical analysis of 138 cases. Medicine 33:291, 1954,
  • 15 Jessar, R. A. , Havers, L. W. and Rogan, C. : Matural history of lupus erythematosus disseminatus. Ann. Int. Med. 38: 717, 1953.
  • 16 Kapcsi, M. K. : Neue Beiträge zur Kenntniss des lupus erythematosus Arch. F. Dermat. syph. 4:36, 1872. 17 — Kawano, K., Miller, L. and Kimmelstiel, P. : Virus - like structures in lupus erythematosus. New Eng. J. Med. 281:1228, 1969.
  • 18 Keil, H. : Relationship between lupus erythematosus and tuberculosis A critical review based on observation at necropcy. Arch. Dermat. and syph. 28:765, 1933.
  • 19 Keith, N. M. and Rowntree, L. G. : A study of renal complications of disseminated lupus erythematosus. Report of four cases. Tr. A. Am. Phys. 37•.487, 1922.
  • 20 — Kelvin, J. : Lupus erythematosus and tuberculin test. Lancet 5:59'7, 1941.
  • 21 — Klemperer, P., Pollack, A. D. and Baehr, G. : On the nature of acute lupus erythematosus. New York State J. Med. 42:2225, 1942.
  • 22 — Klinge, F. : Der Rheumatismus; pathologisch - anatomische und experi• mentell pathologische tatsachen und ihre auswertung fur das arztliche Rheumaproblem. Ergeben D. Allg. U. Path. Anat. 27:1, 1933.
  • 23 — Koets, P. Excretion of urinary 17 - ketosteroids in chronic lupus erythematosus case report. Stanford M. Bull. 9:256, 1951.
  • 24 — Koffler, D, Schur, P. He, Kunkel, H. G. : Immunological studies concerning the nephritis of systemic lupus erythematosus. J. exper. Med. 1967.
  • 25 — Kong, T., Kelum, R. and Haserick, HI : Clinical diagnosis of cardiac involvement in systemic lupus erythematosus. A correlation of clinical and autopsy findings in thirty patients. Circulation 26:7, 1962.
  • 26 — Kren, O. : Zur Kolarung der Pathogenese des lupus Erythematodes acutus. Wien Med. Wchnschr. 86:680, 1936.
  • 27 -— Kunkel, H. R. : Mechanism of renal infury in systemic lupus erythematosus. Arthritis and Rheumatism. 9:725, 1966.
  • 28 — Lee, S. L. : A simple test for L. cell. Am. J. Clin. Path. 21:492, 1951. 29 — Moolten, S. E. and Clark, E. : Viremia in acute hemolytic anemia and in autohemagglutination. Arch. Int. Med. 89:27Ù, 1952.
  • 30 Muehrcke, R. C., Kark, R. M., Pirani, C. L. and Pollack, V. F,. : Lupus nephritisi A Clinical and Pathologic Study based on renal biopsies. Medicine 36:1, 1957. 31 Norton, W. L. : Endothelial inclusions in active lesions in systemic lupus erythematosus. The Lab. and Clin. Med. 74:369, 1969.
  • 32 — Norton, W. Ia., Hurd, E. R., Lewis, D. C. and Ziff, M. : Evidence of microvascular injury in scleroderma and systemic lupus erythematosus; quantitative study of the microvascular bed. The J, Lab, and Olin. Med. 71:919, 1968.
  • 33 — Ormsby, O. S. and Montgomery, H. : Disease of the skin. Ed. 7. Philadelphia, 1948.
  • 34 — Osler, W. : On the visceral complications of erythema exudativum multiforme. Am. J. Med. sc. 110:629, 1895.
  • 35 — Parelhoff, M. E. : Demostration of the LE cell phenomenon in Subacute glomerulonephritis. Sinai Hosp. Bull. 2:12, 1953.
  • 36 — Pincus, T. , Blacklow, N. R. , Grimley, P. M. , Bellanti, J. A. : Glomerular microtubules of systemic lupus erythem.atosus. The Lancet 2: 1058, 1970.
  • 37 — Rayer, P. : Traite théorique et pratique des maladies de la peau. Fondé sur de nouvelles Recherches d' Anatomie et de physiologie pathologiques, Paris, J-B-Bai11iere, 1826.
  • 38 — Rich, A. R. and Gregory, J. E. : Experimental anaphylactic lesions of the coronary arteries of the sclerotic type commonly associated with Rheumatic fever and disseminated lupus erythematosus. Bull. Johns. Hopkins Hosp. 87:549, 1950.
  • 39 — Rose, E. and Pielsbury, D. M. : Acute disseminated lupus erythematosus, systemic disease. Ann. Int. Med. 12:951, 1939.
  • Schur, P. H. and Sandson, J, : Immunologic factors and clinical actiVity in systemic lupus erythematosus. New Eng. J. Med. 278:533, 1968. Shearn, M. A and Pirofsky, B. : Disseminated lupus erythematosus. Arch. Int. Med. 90:790, 1952.
  • Stokes, J. H. , Beerman, H. and Ingraham, N. R. : The lupus arythematosus, concept and attempt at integration. Am. J. Med. Sc. 207 :540, 1944.
  • 43 Tan, E. M. and KunluA H. G. : An immunofluorescent study of the skin lesions in systemic lupus erythematosus Arthritis and Rheumatism. 9:37, 1966.
  • 44 Walsh, J. and Egan, R. : The reliability of L. E. test. New Eng. J. Med. 246:775, 1952.
  • 45 — Welsh, A. L. . Specificity of Streptococci isolated from patients with skin diseases. Studies on pemphigus, dermatitis herpetiformis, lupus erythematosus and erythema multiforme J. Invest. Dermat. 10:305, 1948.
There are 40 citations in total.

Details

Primary Language Turkish
Subjects Infant and Child Health
Journal Section Research Article
Authors

Binnaz Ege This is me

Publication Date June 30, 1974
IZ https://izlik.org/JA35CZ42RD
Published in Issue Year 1974 Volume: 27 Issue: 1-2

Cite

APA Ege, B. (1974). Sistemik Lupus Eritematosis’in Klinik Mikroskopik Ve Elektron Mikroskopik İncelenmesi. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 27(1-2), 371-388. https://izlik.org/JA35CZ42RD
AMA 1.Ege B. Sistemik Lupus Eritematosis’in Klinik Mikroskopik Ve Elektron Mikroskopik İncelenmesi. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1974;27(1-2):371-388. https://izlik.org/JA35CZ42RD
Chicago Ege, Binnaz. 1974. “Sistemik Lupus Eritematosis’in Klinik Mikroskopik Ve Elektron Mikroskopik İncelenmesi”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 27 (1-2): 371-88. https://izlik.org/JA35CZ42RD.
EndNote Ege B (June 1, 1974) Sistemik Lupus Eritematosis’in Klinik Mikroskopik Ve Elektron Mikroskopik İncelenmesi. Ankara Üniversitesi Tıp Fakültesi Mecmuası 27 1-2 371–388.
IEEE [1]B. Ege, “Sistemik Lupus Eritematosis’in Klinik Mikroskopik Ve Elektron Mikroskopik İncelenmesi”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 27, no. 1-2, pp. 371–388, June 1974, [Online]. Available: https://izlik.org/JA35CZ42RD
ISNAD Ege, Binnaz. “Sistemik Lupus Eritematosis’in Klinik Mikroskopik Ve Elektron Mikroskopik İncelenmesi”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 27/1-2 (June 1, 1974): 371-388. https://izlik.org/JA35CZ42RD.
JAMA 1.Ege B. Sistemik Lupus Eritematosis’in Klinik Mikroskopik Ve Elektron Mikroskopik İncelenmesi. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1974;27:371–388.
MLA Ege, Binnaz. “Sistemik Lupus Eritematosis’in Klinik Mikroskopik Ve Elektron Mikroskopik İncelenmesi”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 27, no. 1-2, June 1974, pp. 371-88, https://izlik.org/JA35CZ42RD.
Vancouver 1.Binnaz Ege. Sistemik Lupus Eritematosis’in Klinik Mikroskopik Ve Elektron Mikroskopik İncelenmesi. Ankara Üniversitesi Tıp Fakültesi Mecmuası [Internet]. 1974 Jun. 1;27(1-2):371-88. Available from: https://izlik.org/JA35CZ42RD