Investigation of Amyloidosis with Various Methods

Year 1970, Volume: 23 Issue: 4, 1090 - 1098, 31.08.1970

Orhan Seyfi Sardaş

https://izlik.org/JA88FD32EC

Abstract

Böbrek biopsisi ve rektum biopsisi yapılan 26 vak'ada, böbrek biopsisi ile 10/0 962, rektum biopsisi ile 53.85 oranında pozitif netice alınmıştır.
21 vak'aya tatbik edilen diş eti biopsisi ancak bir vak'ada müsbet netice vermiştir. Bu bakımdan diş eti biopsisi amiloid teşhisi için yeterli bir metot değildir.
22 amiloid vak'asına edilen Congo - red testi, 6 vak'ada boyanın 10/0 90 - 100 arasında tutulmasından dolayı kati amiloid teşhisi konmuştur.
Böbrek amiloidozisin teşhisinde en emin ve kati yol böbrek biopsisidir. Böbrek biopsisi' yapılmayan vak'alara rektum biopsisi ve Congo - red testinin tatbiki uygundur.

Keywords

Amiloidoz , Biyopsi yöntemleri , Congo red testi

Ethical Statement

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Supporting Institution

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Project Number

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Thanks

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Çeşitli Yöntemlerle Amiloidozun Araştırılması

https://izlik.org/JA88FD32EC

Abstract

Investigation of renal amiloijdosis with different methods. in a series of 26 patients who had both renal and rectal biopsies, a positif result was obtained in 96, 2 % of renal and in 53, 85 % Cf rectal biopsies. The gingival biopsy done on 21 patients were all negative except in one. For this reason gingival biopsy is an unsatisfactoıy test for the diagnosis of renal amyloidosis.
The congo - red test Was carried on the 22 patients and the correct diagnosis was arrived only in 6 patients ıwhom there was 90 - 100 % retantion of the dye. İn our hands, the renal biopsy turn out to be a reliable test in the diagnosis of renal amyloidosis. Rectal biopsy and congo - red test is recommended only in the patients who had not a renal biopsy.

Keywords

Amyloidosis , Biopsy Methods , Congo Red Test

Ethical Statement

-

Supporting Institution

-

Project Number

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Thanks

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References

• 1 — PAUNZ, L: Kreislau probleme der niere. Magy, orv. Arch. 32, 25, 1931.
• 2 — STRAUST, M. AND WELT, L: Disease of the kidney, Little, Brown and Company. Boston. 1963.
• 3 — HAMBURGER, J. RiCHET G: Nephrology Volum 11, Saunders Company. 1968.
• 4 — SARDAS O. S: Perkütan Böbrek Biopiikasyonlarl. A. tj. Fakültesi Mec. vol : XXII, sayi : IV, 1969
• 5 — SARDAS O. S. SÖKMEN C : 304 vak'ada yapllan böbrek biopsisi neticeleri. XX. Milli TIÞ Kongresi Istanbul. 1968.
• 6 MtSSMAHL, H. P : Diagnose einer primaren, perikollagenen Amiloidose mit Hilfe der rektum biopsie. Dtsch. med. Wschr. 89: 122, 1964.
• 7 — ALY, F. W., BRAUN, H. J. and. MISSMAHL, H. P.: Amyloid involvement and monoclonal immunoglobulins. Bayer-symposium 1, Springerverlag, 1969.
• 8 — SELIKOFF J. J. et ROBITZEK E. H.: Gingival biopsy for the diagnosis of generalized amyloidosis Am. J. Path. 23: 1099, 1947.
• 9 — GAFNÏ, J. and SOHAR, E. : Rectal biopsy for the diagnosis of amyloidosis The Amer. Jour. of the Med. Scien. 240, 3, 1061, 1960.
• 10 — DUCROT, H., MONTERA, H., MERY, J. et RUEFF, B.: La biopsise rectale est-el.le la methode choilx pour le diagnostic de la maladie amyloide. Société de Nephrologie. 67, 6, 432, 1961.
• 11 — MORGON, W. K. et MULES, J: Ð. The intravenous Congo-red test: Amer. J. Med. sci. 239, 61, 1960.
• 12 — DUCROT, H. et SLAMA, R.: Les Conditions de diagnostic de L'amyloid renale. In Actutualités Nephrologiques L'hospital Necker, 1 vol. Paris 1963, Ed. Med. mammorian, p. 115.
• 13 — BLUM. A and SOHAR, E.: Diagnosis of amyloidosis Ancillary procedures. Lancet 1: 721, 1962.
• .14 — FENTEM, P. H., TURNBERG L. A. and WORMSLEY, K. G.: Biopsy of the Rectum as an aid to the diagnosis of amyloidosis.. Brit. Med. Jour. Feb. 10: 364, 1962.
• 15 — ARAPAKIS, G. et TRIBE, C. R.: Amyloidosis in rheumatoid arthritis. Ann. Rheu. Dis. 22: 256, 1963.
• 16 — UNGER, P. N., ZUCKERBROD, M, BECK, G. J., and STÐLLÐ, J. M.: Study of disipperance Congo red from blood Of non-amyloid subjects and petients with amiloidosig J. Clin. .Ínves 27: 111, 1948.
• 17 — TUBïS, M, BLAHD, W. H., and ENDOW, J. S.: Use of radioiondinated, Congo red in study of amyloidosis. Nuclear Medicine 3: 25, 1962.
• 18 — COHEN, A. S.: Amyloidosis The New Eng. Lou. of 277, 12: 628, 1967.