Research Article

Mechanism of Tolerance and Addiction to Morphine

Volume: 23 Number: 3 June 30, 1970
Cankat Tulunay
TR EN

Mechanism of Tolerance and Addiction to Morphine

Abstract

Literature information on morphine tolerance and addiction was collected and biogenic amines involved in the mechanism of these events were discussed. In particular, the relationship between brain catecholamines and serotonin and morphine tolerance and addiction was emphasized. The relationship between protein synthesis and morphine tolerance, which has recently gained great importance, was mentioned.

Keywords

addiction, mekanizma, morfin

References

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  2. 2-AKERA, T.. BRODY, T. M.: 'The addiction cycle to narcotics in the rat and its relation to cathecholamines. Biochem. Pharmac., 17: 675, 1968.
  3. 3-COHEN, M., KEATS, A. S., KRİVORY, W. UNGAR, G.: Efect of actinomycin D on morphine tolerance, Proc. Soc. Exp. Biol. Med, 119: 381, 1965.
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  7. 7-COX, B. M., GINSBURG, M., OSMAN, O. H.: Acute tolerance to narcotic analgesic drugs in rats. Br. J. Phanmac. Chemother. 88: 245, 1968.
  8. 8-COX, B. M., GINSBURG, M.: Is there a relationship between protein synihesis and tolerance to analgesic drug. Scientific of Drug Dependence. s. 77-86, ed. Steinberg, H. Churchill Ltd. 1969.
  9. 9-EDDY, N.B.: Action on the nervous system. The Pharmacology of the Opium Alkaloids, I, U.S.A. Pub. Health Rep. Supp. 165. ed. Kruger, H. Edy, N. B., Sumwalt, M., Weshington, 1941.
  10. 10-EDDI, N. B.: Tolerance and adiction. The Pharmacology of the Opium Alkaloids, 1. s. 719-757. Ed. Kruger, H., Eddy, N. B., Sumwalt M., U.S.A. Pub. Hip. Rep. Supp. 165, Washington, 1941.
APA
Tulunay, C. (1970). Mechanism of Tolerance and Addiction to Morphine. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 23(3), 914-930. https://izlik.org/JA44AC58WU
AMA
1.Tulunay C. Mechanism of Tolerance and Addiction to Morphine. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1970;23(3):914-930. https://izlik.org/JA44AC58WU
Chicago
Tulunay, Cankat. 1970. “Mechanism of Tolerance and Addiction to Morphine”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 23 (3): 914-30. https://izlik.org/JA44AC58WU.
EndNote
Tulunay C (June 1, 1970) Mechanism of Tolerance and Addiction to Morphine. Ankara Üniversitesi Tıp Fakültesi Mecmuası 23 3 914–930.
IEEE
[1]C. Tulunay, “Mechanism of Tolerance and Addiction to Morphine”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 23, no. 3, pp. 914–930, June 1970, [Online]. Available: https://izlik.org/JA44AC58WU
ISNAD
Tulunay, Cankat. “Mechanism of Tolerance and Addiction to Morphine”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 23/3 (June 1, 1970): 914-930. https://izlik.org/JA44AC58WU.
JAMA
1.Tulunay C. Mechanism of Tolerance and Addiction to Morphine. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1970;23:914–930.
MLA
Tulunay, Cankat. “Mechanism of Tolerance and Addiction to Morphine”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 23, no. 3, June 1970, pp. 914-30, https://izlik.org/JA44AC58WU.
Vancouver
1.Cankat Tulunay. Mechanism of Tolerance and Addiction to Morphine. Ankara Üniversitesi Tıp Fakültesi Mecmuası [Internet]. 1970 Jun. 1;23(3):914-30. Available from: https://izlik.org/JA44AC58WU