Palindromic Rheumatism
Abstract
Palindromic rheumatism is a rare rheumatic condition first defined in 1944 by Hench and Rosenberg. Characterized by spontaneous, acute, painful inflammatory swellings in articular and periarticular regions, it presents in recurring episodes without leaving permanent damage. Typically occurring in adults aged 20–40, the disease exhibits monoarticular or, less frequently, polyarticular patterns. Commonly affected joints include fingers, wrists, knees, and shoulders. Attacks begin suddenly, reaching peak intensity within hours and resolve within days. Para-articular symptoms and skin nodules may accompany flares. Diagnosis relies on clinical patterns; lab and radiographic findings are often normal. Prognosis is generally favorable, with occasional progression to rheumatoid arthritis. Treatments range from symptomatic medications (NSAIDs, gold salts) to physical therapy during inactive phases.
Keywords
palindromic rheumatism, recurrent arthritis, para-arthritis, joint inflammation, differential diagnosis
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