Tiroid Hormonobiyojenez Defektlerinin Tanısında Tiroksin Yükleme Testinin Yeri

Selahaddin Koloğlu

TR EN

Tiroid Hormonobiyojenez Defektlerinin Tanısında Tiroksin Yükleme Testinin Yeri

Abstract

Defects in thyroid hormone synthesis, conversion, and action have gained increasing attention in recent years. Although rare in general thyroid pathology, they provide critical insight into thyroid physiology. Diagnostic challenges arise due to limitations in available tests. To address this, a non-radioactive thyroxine loading test was developed and assessed in eight cases of dishormonogenesis. Following oral administration of 3 mg thyroxine, serial hormone measurements were taken. The study demonstrated that this simple method could help identify peripheral conversion defects of T4 to T3. Observations also support a role for these defects in T4-toxicosis cases.

Keywords

thyroid hormonogenesis, thyroxine loading test, T4 to T3 conversion defect, dishormonogenesis, organification defect, Pendred syndrome, T4-toxicosis

References

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Details

Primary Language

English

Subjects

Endocrinology

Journal Section

Research Article

Authors

Selahaddin Koloğlu This is me
Türkiye

Publication Date

December 31, 1981

Submission Date

October 1, 1981

Acceptance Date

December 30, 1981

Published in Issue

Year 1981 Volume: 34 Number: 4

IZ

https://izlik.org/JA39KW25EL

APA

Koloğlu, S. (1981). Tiroid Hormonobiyojenez Defektlerinin Tanısında Tiroksin Yükleme Testinin Yeri. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 34(4), 621-638. https://izlik.org/JA39KW25EL

AMA

1.Koloğlu S. Tiroid Hormonobiyojenez Defektlerinin Tanısında Tiroksin Yükleme Testinin Yeri. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1981;34(4):621-638. https://izlik.org/JA39KW25EL

Chicago

Koloğlu, Selahaddin. 1981. “Tiroid Hormonobiyojenez Defektlerinin Tanısında Tiroksin Yükleme Testinin Yeri”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 34 (4): 621-38. https://izlik.org/JA39KW25EL.

EndNote

Koloğlu S (December 1, 1981) Tiroid Hormonobiyojenez Defektlerinin Tanısında Tiroksin Yükleme Testinin Yeri. Ankara Üniversitesi Tıp Fakültesi Mecmuası 34 4 621–638.

IEEE

[1]S. Koloğlu, “Tiroid Hormonobiyojenez Defektlerinin Tanısında Tiroksin Yükleme Testinin Yeri”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 34, no. 4, pp. 621–638, Dec. 1981, [Online]. Available: https://izlik.org/JA39KW25EL

ISNAD

Koloğlu, Selahaddin. “Tiroid Hormonobiyojenez Defektlerinin Tanısında Tiroksin Yükleme Testinin Yeri”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 34/4 (December 1, 1981): 621-638. https://izlik.org/JA39KW25EL.

JAMA

1.Koloğlu S. Tiroid Hormonobiyojenez Defektlerinin Tanısında Tiroksin Yükleme Testinin Yeri. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1981;34:621–638.

MLA

Koloğlu, Selahaddin. “Tiroid Hormonobiyojenez Defektlerinin Tanısında Tiroksin Yükleme Testinin Yeri”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 34, no. 4, Dec. 1981, pp. 621-38, https://izlik.org/JA39KW25EL.

Vancouver

1.Selahaddin Koloğlu. Tiroid Hormonobiyojenez Defektlerinin Tanısında Tiroksin Yükleme Testinin Yeri. Ankara Üniversitesi Tıp Fakültesi Mecmuası [Internet]. 1981 Dec. 1;34(4):621-38. Available from: https://izlik.org/JA39KW25EL

Tiroid Hormonobiyojenez Defektlerinin Tanısında Tiroksin Yükleme Testinin Yeri

The Role of the Thyroxine Loading Test in Diagnosing Defects of Thyroid Hormonobiogenesis

Abstract

Tiroid Hormonobiyojenez Defektlerinin Tanısında Tiroksin Yükleme Testinin Yeri

Abstract

Keywords

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

IZ

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