Diabetik Nefropati
Abstract
Four cases of diabetic glomerulosclerosis, diagnosed three by kidney biopsy and one by autopsy, were presented in our clinic. It was noted that two of the patients were well under 40 years of age, and the triad of nephrotic syndrome, hypertension, and proteinuria was observed in only one case. We recommended early diagnosis with kidney biopsy for all diabetic patients with mild or severe proteinuria. Histopathological examination of the five cases revealed basement membrane thickening, atherosclerosis, hyaline deposition in efferent arterioles, and hyaline nodules in the mesangium, all of which are characteristic of diabetic glomerulosclerosis. In the remaining cases, diffuse basement membrane thickening and hyaline deposition in arterioles were observed.
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References
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