Results Obtained with Radioactive Iodine Treatment in Non-Inflammatory Hyperthyroidism Cases and Investigation of the Most Appropriate Practical Criteria in Determining the Doses to be Given (X)

Selahattin Koloğlu

Systematic Reviews and Meta Analysis

İltihaplı Hipertiroidi Olgularında Radyoaktif İyot Tedavisi ile Elde Edilen Sonuçlar ve Verilecek Dozların Belirlenmesinde En Uygun Pratik Kriterlerin Araştırılması (X)

Year 1959, Volume: 12 Issue: 3-4, 1 - 21, 31.12.1959

Selahattin Koloğlu

https://izlik.org/JA97EW54EM

Abstract

Hipertiroidi tedavisinde radyoaktif iyotun kullanımı, klasik tedavi yöntemlerine göre daha etkili sonuçlar vermektedir. Bu çalışmada, 1956 yılından itibaren Paris Broussais Hastanesi'nde radyoaktif iyot ile tedavi edilen 302 hipertiroidi hastasının sonuçları analiz edilmiştir. Amaç, uygulanan tedaviye verilen yanıtı değerlendirecek ve yeni doz ihtiyacını gösterecek en uygun kriterleri belirlemektir. Bulgular, klinik bulguların tedaviye rehberlik etmede en güvenilir yöntem olduğunu göstermiştir. Ayrıca PBI testi en güvenilir biyokimyasal test olarak öne çıkmıştır. Klinik ve laboratuvar verilerin birlikte değerlendirilmesi, daha güvenli ve etkili doz ayarlamalarına olanak tanımaktadır.

Keywords

Hipertiroidi , Radyoaktif iyot , Tiroid fonksiyon testleri

References

1. BAUER F. K., GODWIN W. E. - Acne and Gynaecomastia following radioactive iodine therapy for hyperthyroidism. J. of Clin. Endocr. and Metab., 1951, 11, pp. 1574–1576.
2. BAUER F. K. - Radioactive iodine uptake in treated hyperthyroidism. Am. J. Med. Sc., 1952, 223, pp. 495–501.
3. BAUER F. K. - Treatment of hyperthyroidism with individually calculated doses of radioactive iodine. A.M.A. Arch. Int. Med., 1957, 99(2), 194–201.
4. BEIERWALTES W. H. - The value of radioactive iodine and protein-bound iodine in the diagnosis of thyrotoxicosis. Ann. Int. Med., 1956, 44, pp. 41–50.
5. BERMAN M., BECKER D. V. - The use of radioactive iodine in the treatment of Graves' disease. J. of Clin. Endocr. and Metab., 1957, 10, pp. 1222–1228.
6. BRICAIRE H. - Position actuelle du traitement de la maladie de Basedow. Acquisitions Médicales Récentes, Flammarion, 1959.
7. BESSON R. - Technique de dosage de l’iode protégé applicable en clinique. Rev. Fr. d’Études Cliniques et Biologiques, 1956, 1(6), 706.
8. BLOOMFIELD G. W. - Treatment of thyrotoxicosis with radioactive iodine: review of 140 cases. Br. Med. J., 1955, p. 1223.
9. BURROWS B. A., ROSSI J. F. - Thyroidal uptake of stable iodine compared with serum concentration of protein-bound iodine. J. Clin. Endocr., 1953, 13, pp. 1358–1368.
10. CLARK D. E., RULE J. J. H. - Five year experience with radioactive iodine in treatment of hyperthyroidism. JAMA, 1952, 150, pp. 1269–1272.
11. DECOURT J. - Étude de la fonction thyroïdienne par l’iode radioactif. Presse Médicale, 1958, 77, pp. 1723–1726.
12. FAUVERT R. - L’utilisation des isotopes radioactifs dans le diagnostic médical. Thérapie, 1957, 5, pp. 737–746.
13. FAUVERT R. - Traitement de l’hyperthyroïdie par l’iode radioactif. La Semaine des Hôpitaux, 1954, 36, pp. 4236.
14. FELLINGER K. - The disturbances in iodine metabolism produced by thyroid surgery. J. of Clin. Endocr. and Met., 1957, 17(4), pp. 483–501.
15. DE GENNES L. - Le traitement de la maladie de Basedow par l’iode radioactif. La Presse Médicale, 1956, 42(3).
16. DE GENNES L. - Les nouveaux traitements de la maladie de Basedow. Le Monde Médical, 1956, 998, p. 129.
17. DE GENNES L. - Étude statistique de 138 hyperthyroïdies traitées par l’iode radioactif. La Semaine des Hôpitaux, 1959, 20, p. 1473.
18. GOUGEROT L. - Quelques notions de physique sur les radio-isotopes. Revue du Praticien, 1958, 23, pp. 2633–2646.
19. GILBERT-DREYFUS Z. M. - Les syndromes musculaires hypothyroïdiens au cours du traitement de l’hyperthyroïdie. Ann. d’Endocr., 1954, 15(2), pp. 153–157.
20. GILBERT-DREYFUS - Les traitements actuels de la maladie de Basedow. Revue du Praticien, 1957, 7(18), pp. 1995–2003.
21. HAMOLSKY M. W., FREEDBERG A. S. - The exchangeable thyroid hormonal pool; its magnitude and turnover in various thyroid states. J. of Clin. Invest., 1953, 32, pp. 453–457.
22. KELLY E. F. J. - Observations on the circulation of thyroid weight using empirical formula. J. Clin. Endocr. and Metab., 1954, 14, pp. 326–335.
23. KLOTZ H. P., CAROIT T. - Étude clinique des effets obtenus par l’iode radioactif dans le traitement de l’hyperthyroïdie (à propos de 31 cas). Ann. d’Endocr., 1953, 14(5), pp. 838–856.
24. LARSON L. G., RAGNAULT I. - Study of iodine concentrating function of thyroid after treatment with radioactive iodine. Acta Radiol., 1953, 39, pp. 477–484.
25. LUDDECKE H. F. - Basal metabolic rate, protein-bound iodine uptake: a comparative study. Ann. Int. Med., 1958, 49(2), pp. 305–309.
26. Mac CULLAGH E. P. - On the choice of treatment for hyperthyroidism. Ann. of Int. Med., 1956, 44, pp. 292–301.
27. Mac GREGOR A. G. - Simplified radioactive iodine therapy. Br. Med. J., 1957, 5071, pp. 495–497.
28. MALOOF F., CHAPMAN E. M. - Responses to radioactive iodine therapy in hyperthyroidism and cardiac problems. J. of Clin. Endocr., 1951, 2, p. 1296.
29. MYANT N. M. - Prognostic value in early tests of thyroid function after treatment of thyrotoxicosis. Br. J. of Radiol., 1953, 26(303), p. 139.
30. PERRAULT M. - Quelques signes injustement négligés de la maladie de Basedow. La Semaine des Hôpitaux, 1958, 34, pp. 2728–2730.
31. ROBBINS J. - Identification of thyroglobulin in human serum after large doses of radioactive iodine. Trans. Am. Goiter Assoc., 1954, pp. 402–419.
32. ROBBINS J. - Thyroglobulin in serum after radioactive iodine therapy: salting out. J. Biol. Chem., 1954, 208, pp. 377–386.
33. SCHULTZ A. - Relationship between clinical severity of hyperthyroidism and results of thyroid function tests. J. Clin. Endocr., 1958, 6, pp. 629–635.
34. SCHULTZ A. L., ZIEVEL L. - Alteration in thyroid radioactive iodine uptake, BMR, and serum cholesterol following treatment of hypothyroidism. Am. J. Med., 1956, 20, p. 30.
35. SILVER S. - Pitfalls in diagnostic use of radioactive iodine. JAMA, 1955, 159, pp. 1–15.
36. SWYNGEDAUW J., LINOUETTE M. - Appréciation des résultats du traitement des hyperthyroïdies traitées par l’iode radioactif. J. de Radiol. d’Électrol. et de Méd. Nucl., 1957, 88(5-6), pp. 593–594.
37. SHELINE G. E., LINDSAY S. - Occurrence of thyroid nodules in children following radioactive iodine therapy. J. Clin. Endocr., 1959, 19(1), pp. 127–138.
38. TUBILANA M., VALEE G. - Traitement de l’hyperthyroïdie par l’iode radioactif. Thérapie, 1957, 12(5), pp. 813–824.
39. TUBIANA M., DUTREIX J. - Résultats du traitement de 115 cas d’hyperthyroïdies par l’iode radioactif. Presse Médicale, 1953, 61, pp. 807–809.
40. TUBIANA M. - L’iode radioactif et la thyroïde. Revue du Praticien, 1958, 23, pp. 2683–2699.
41. VIRSCHER de, SCHREVEL J. de - Fonction thyroïdienne et radioactivité du sang après administration du radioiode. Ann. d’Endocr., 1953, 3, p. 460.
42. WILKINS L. - The diagnosis and treatment of endocrine disorders in childhood and adolescence. Charles C. Thomas, Springfield, Illinois, 1957.
43. WILSON G. M., KILPATRICK R. - Thyroid neoplasm following irradiation. Br. Med. J., 1958, October 18, pp. 929–934.
44. WERNER S. C. - Acute leukemia after radioactive iodine therapy for hyperthyroidism. JAMA, 1957, 165(12), pp. 1558–1560.

Results Obtained with Radioactive Iodine Treatment in Non-Inflammatory Hyperthyroidism Cases and Investigation of the Most Appropriate Practical Criteria in Determining the Doses to be Given (X)

Year 1959, Volume: 12 Issue: 3-4, 1 - 21, 31.12.1959

Selahattin Koloğlu

https://izlik.org/JA97EW54EM

Abstract

Radioactive iodine has proven to be more effective than classical treatment modalities in the management of hyperthyroidism. This study analyzes the outcomes of 302 hyperthyroid patients treated with radioactive iodine at Paris Broussais Hospital since 1956. The goal is to determine which practical criteria best indicate the adequacy of treatment and the need for additional dosing. The findings emphasize that clinical signs are the most reliable indicators of therapeutic response. Among laboratory tests, the protein-bound iodine (PBI) assay showed the highest diagnostic accuracy. Combining clinical judgment with laboratory assessments enables safer and more effective dosing decisions.

Keywords

Hyperthyroidism , Radioactive iodine , Thyroid function tests

References

1. BAUER F. K., GODWIN W. E. - Acne and Gynaecomastia following radioactive iodine therapy for hyperthyroidism. J. of Clin. Endocr. and Metab., 1951, 11, pp. 1574–1576.
2. BAUER F. K. - Radioactive iodine uptake in treated hyperthyroidism. Am. J. Med. Sc., 1952, 223, pp. 495–501.
3. BAUER F. K. - Treatment of hyperthyroidism with individually calculated doses of radioactive iodine. A.M.A. Arch. Int. Med., 1957, 99(2), 194–201.
4. BEIERWALTES W. H. - The value of radioactive iodine and protein-bound iodine in the diagnosis of thyrotoxicosis. Ann. Int. Med., 1956, 44, pp. 41–50.
5. BERMAN M., BECKER D. V. - The use of radioactive iodine in the treatment of Graves' disease. J. of Clin. Endocr. and Metab., 1957, 10, pp. 1222–1228.
6. BRICAIRE H. - Position actuelle du traitement de la maladie de Basedow. Acquisitions Médicales Récentes, Flammarion, 1959.
7. BESSON R. - Technique de dosage de l’iode protégé applicable en clinique. Rev. Fr. d’Études Cliniques et Biologiques, 1956, 1(6), 706.
8. BLOOMFIELD G. W. - Treatment of thyrotoxicosis with radioactive iodine: review of 140 cases. Br. Med. J., 1955, p. 1223.
9. BURROWS B. A., ROSSI J. F. - Thyroidal uptake of stable iodine compared with serum concentration of protein-bound iodine. J. Clin. Endocr., 1953, 13, pp. 1358–1368.
10. CLARK D. E., RULE J. J. H. - Five year experience with radioactive iodine in treatment of hyperthyroidism. JAMA, 1952, 150, pp. 1269–1272.
11. DECOURT J. - Étude de la fonction thyroïdienne par l’iode radioactif. Presse Médicale, 1958, 77, pp. 1723–1726.
12. FAUVERT R. - L’utilisation des isotopes radioactifs dans le diagnostic médical. Thérapie, 1957, 5, pp. 737–746.
13. FAUVERT R. - Traitement de l’hyperthyroïdie par l’iode radioactif. La Semaine des Hôpitaux, 1954, 36, pp. 4236.
14. FELLINGER K. - The disturbances in iodine metabolism produced by thyroid surgery. J. of Clin. Endocr. and Met., 1957, 17(4), pp. 483–501.
15. DE GENNES L. - Le traitement de la maladie de Basedow par l’iode radioactif. La Presse Médicale, 1956, 42(3).
16. DE GENNES L. - Les nouveaux traitements de la maladie de Basedow. Le Monde Médical, 1956, 998, p. 129.
17. DE GENNES L. - Étude statistique de 138 hyperthyroïdies traitées par l’iode radioactif. La Semaine des Hôpitaux, 1959, 20, p. 1473.
18. GOUGEROT L. - Quelques notions de physique sur les radio-isotopes. Revue du Praticien, 1958, 23, pp. 2633–2646.
19. GILBERT-DREYFUS Z. M. - Les syndromes musculaires hypothyroïdiens au cours du traitement de l’hyperthyroïdie. Ann. d’Endocr., 1954, 15(2), pp. 153–157.
20. GILBERT-DREYFUS - Les traitements actuels de la maladie de Basedow. Revue du Praticien, 1957, 7(18), pp. 1995–2003.
21. HAMOLSKY M. W., FREEDBERG A. S. - The exchangeable thyroid hormonal pool; its magnitude and turnover in various thyroid states. J. of Clin. Invest., 1953, 32, pp. 453–457.
22. KELLY E. F. J. - Observations on the circulation of thyroid weight using empirical formula. J. Clin. Endocr. and Metab., 1954, 14, pp. 326–335.
23. KLOTZ H. P., CAROIT T. - Étude clinique des effets obtenus par l’iode radioactif dans le traitement de l’hyperthyroïdie (à propos de 31 cas). Ann. d’Endocr., 1953, 14(5), pp. 838–856.
24. LARSON L. G., RAGNAULT I. - Study of iodine concentrating function of thyroid after treatment with radioactive iodine. Acta Radiol., 1953, 39, pp. 477–484.
25. LUDDECKE H. F. - Basal metabolic rate, protein-bound iodine uptake: a comparative study. Ann. Int. Med., 1958, 49(2), pp. 305–309.
26. Mac CULLAGH E. P. - On the choice of treatment for hyperthyroidism. Ann. of Int. Med., 1956, 44, pp. 292–301.
27. Mac GREGOR A. G. - Simplified radioactive iodine therapy. Br. Med. J., 1957, 5071, pp. 495–497.
28. MALOOF F., CHAPMAN E. M. - Responses to radioactive iodine therapy in hyperthyroidism and cardiac problems. J. of Clin. Endocr., 1951, 2, p. 1296.
29. MYANT N. M. - Prognostic value in early tests of thyroid function after treatment of thyrotoxicosis. Br. J. of Radiol., 1953, 26(303), p. 139.
30. PERRAULT M. - Quelques signes injustement négligés de la maladie de Basedow. La Semaine des Hôpitaux, 1958, 34, pp. 2728–2730.
31. ROBBINS J. - Identification of thyroglobulin in human serum after large doses of radioactive iodine. Trans. Am. Goiter Assoc., 1954, pp. 402–419.
32. ROBBINS J. - Thyroglobulin in serum after radioactive iodine therapy: salting out. J. Biol. Chem., 1954, 208, pp. 377–386.
33. SCHULTZ A. - Relationship between clinical severity of hyperthyroidism and results of thyroid function tests. J. Clin. Endocr., 1958, 6, pp. 629–635.
34. SCHULTZ A. L., ZIEVEL L. - Alteration in thyroid radioactive iodine uptake, BMR, and serum cholesterol following treatment of hypothyroidism. Am. J. Med., 1956, 20, p. 30.
35. SILVER S. - Pitfalls in diagnostic use of radioactive iodine. JAMA, 1955, 159, pp. 1–15.
36. SWYNGEDAUW J., LINOUETTE M. - Appréciation des résultats du traitement des hyperthyroïdies traitées par l’iode radioactif. J. de Radiol. d’Électrol. et de Méd. Nucl., 1957, 88(5-6), pp. 593–594.
37. SHELINE G. E., LINDSAY S. - Occurrence of thyroid nodules in children following radioactive iodine therapy. J. Clin. Endocr., 1959, 19(1), pp. 127–138.
38. TUBILANA M., VALEE G. - Traitement de l’hyperthyroïdie par l’iode radioactif. Thérapie, 1957, 12(5), pp. 813–824.
39. TUBIANA M., DUTREIX J. - Résultats du traitement de 115 cas d’hyperthyroïdies par l’iode radioactif. Presse Médicale, 1953, 61, pp. 807–809.
40. TUBIANA M. - L’iode radioactif et la thyroïde. Revue du Praticien, 1958, 23, pp. 2683–2699.
41. VIRSCHER de, SCHREVEL J. de - Fonction thyroïdienne et radioactivité du sang après administration du radioiode. Ann. d’Endocr., 1953, 3, p. 460.
42. WILKINS L. - The diagnosis and treatment of endocrine disorders in childhood and adolescence. Charles C. Thomas, Springfield, Illinois, 1957.
43. WILSON G. M., KILPATRICK R. - Thyroid neoplasm following irradiation. Br. Med. J., 1958, October 18, pp. 929–934.
44. WERNER S. C. - Acute leukemia after radioactive iodine therapy for hyperthyroidism. JAMA, 1957, 165(12), pp. 1558–1560.

There are 44 citations in total.

Details

Primary Language	English
Subjects	Endocrinology
Journal Section	Systematic Reviews and Meta Analysis
Authors	Selahattin Koloğlu This is me
Publication Date	December 31, 1959
IZ	https://izlik.org/JA97EW54EM
Published in Issue	Year 1959 Volume: 12 Issue: 3-4

Cite

APA	Koloğlu, S. (1959). Results Obtained with Radioactive Iodine Treatment in Non-Inflammatory Hyperthyroidism Cases and Investigation of the Most Appropriate Practical Criteria in Determining the Doses to be Given (X). Ankara Üniversitesi Tıp Fakültesi Mecmuası, 12(3-4), 1-21. https://izlik.org/JA97EW54EM
AMA	1.Koloğlu S. Results Obtained with Radioactive Iodine Treatment in Non-Inflammatory Hyperthyroidism Cases and Investigation of the Most Appropriate Practical Criteria in Determining the Doses to be Given (X). Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1959;12(3-4):1-21. https://izlik.org/JA97EW54EM
Chicago	Koloğlu, Selahattin. 1959. “Results Obtained With Radioactive Iodine Treatment in Non-Inflammatory Hyperthyroidism Cases and Investigation of the Most Appropriate Practical Criteria in Determining the Doses to Be Given (X)”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 12 (3-4): 1-21. https://izlik.org/JA97EW54EM.
EndNote	Koloğlu S (December 1, 1959) Results Obtained with Radioactive Iodine Treatment in Non-Inflammatory Hyperthyroidism Cases and Investigation of the Most Appropriate Practical Criteria in Determining the Doses to be Given (X). Ankara Üniversitesi Tıp Fakültesi Mecmuası 12 3-4 1–21.
IEEE	[1]S. Koloğlu, “Results Obtained with Radioactive Iodine Treatment in Non-Inflammatory Hyperthyroidism Cases and Investigation of the Most Appropriate Practical Criteria in Determining the Doses to be Given (X)”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 12, no. 3-4, pp. 1–21, Dec. 1959, [Online]. Available: https://izlik.org/JA97EW54EM
ISNAD	Koloğlu, Selahattin. “Results Obtained With Radioactive Iodine Treatment in Non-Inflammatory Hyperthyroidism Cases and Investigation of the Most Appropriate Practical Criteria in Determining the Doses to Be Given (X)”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 12/3-4 (December 1, 1959): 1-21. https://izlik.org/JA97EW54EM.
JAMA	1.Koloğlu S. Results Obtained with Radioactive Iodine Treatment in Non-Inflammatory Hyperthyroidism Cases and Investigation of the Most Appropriate Practical Criteria in Determining the Doses to be Given (X). Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1959;12:1–21.
MLA	Koloğlu, Selahattin. “Results Obtained With Radioactive Iodine Treatment in Non-Inflammatory Hyperthyroidism Cases and Investigation of the Most Appropriate Practical Criteria in Determining the Doses to Be Given (X)”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 12, no. 3-4, Dec. 1959, pp. 1-21, https://izlik.org/JA97EW54EM.
Vancouver	1.Koloğlu S. Results Obtained with Radioactive Iodine Treatment in Non-Inflammatory Hyperthyroidism Cases and Investigation of the Most Appropriate Practical Criteria in Determining the Doses to be Given (X). Ankara Üniversitesi Tıp Fakültesi Mecmuası [Internet]. 1959 Dec. 1;12(3-4):1-21. Available from: https://izlik.org/JA97EW54EM

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