Case Report
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Anti̇hi̇pertansi̇f İlâçlarin Esanti̇yel Hi̇pertansi̇yon Tedavi̇si̇ndeki̇ Yerleri̇

Year 1959, Volume: 12 Issue: 3-4, 22 - 35, 31.12.1959
https://izlik.org/JA64BJ56DS

Abstract

Bu çalışmada, antihipertansif ilaçların esansiyel hipertansiyon tedavisindeki yeri klinik vakalar üzerinden incelenmiştir. Toplam 17 hasta uzun dönem izlenmiş, bunlardan 2’si habis hipertansiyon olup böbrek yetmezliği mevcuttur. Antihipertansif ilaçların dikkatli seçimi, hastanın klinik durumuna göre belirlenmeli ve ani tansiyon düşüşlerinin riskleri göz önünde bulundurulmalıdır. Klinik bulgularla birlikte farmakodinamik özellikler dikkate alınarak uygulanan tedaviler bazı gruplarda olumlu sonuçlar verirken, bazı gruplarda özellikle habis hipertansiyonda prognozu değiştirmemektedir.

References

  • 1. Freis D. E. Recent Developments in the Treatment of Hypertension. The Medical Clinics of North America, March 1954.
  • 2. Freis E. D. and Others. The Hemodynamic Effects of Hexamethonium in Man. J. Clin. Investigation, 31: 629, 1957.
  • 3. Freis E. D., Finnerty F. A. Jr., Schnaper H. W., Johnson R. E. The Treatment of Hypertension with Hexamethonium. Circulation, 5: 20, 1952.
  • 4. Frank A., Finnerty Jr. M.D. The Use of 1-Hydrazinophthalazine (Apresoline) in the Management of Hypertension Appearing in Early Pregnancy. The American Journal of Medical Sciences, 222: 140, 1954.
  • 5. Goodman L. E., Gilman A. The Pharmacological Basis of Therapeutics, 2nd Edition, Macmillan Co, 1955, pp. 747–757; 633–638.
  • 6. Hafkenschiel J. H. Newer Drugs in Treatment of Hypertension. Advances in Medicine and Surgery, Univ. of Pennsylvania, W.B. Saunders Co., 1952.
  • 7. Kempner W. Treatment of Hypertensive Vascular Disease with Rice Diet. Am. J. Med., 4: 545–577, 1948.
  • 8. Hoobler S. W., Corley R. W., Kabza T. G., Loyke H. F. Treatment of Hypertension with Oral Protoveratrine. Ann. Intern. Med., 37: 465, 1952.
  • 9. Meilman E., Krayer O. Clinical Studies on Veratrum Alkaloids II. The Dose Response Relationship of Protoveratrine in Hypertension. Circulation, 6: 212, 1952.
  • 10. Merril H. D. Apresoline in the Treatment of Hypertensive Disease: A Clinical Trial with a Control Group. Am. J. Med. Sci., Dec 1953, p. 623.
  • 11. Moyer J. H. Intramuscular Veriloid as a Hypotensive Agent. Am. J. Med. Sci., Nov 1953, p. 477.
  • 12. Moyer J. H. Results with Oral Hexamethonium Alone and in Combination with 1-Hydrazinophthalazine (Apresoline) in Hypertension Therapy. Am. J. Med. Sci., 225: 379, 1953.
  • 13. Moyer J. H., Russel A. H., Handley, Mills L. C. Effect of Hexamethonium Chloride on Cardiovascular and Renal Hemodynamics and Electrolyte Excretion. J. Pharmacol. Exp. Ther., 106(6): 152, 1952.
  • 14. Kirkendall W. M., Culbertson J. W. Some Effects of Hexamethonium on Renal Circulation. J. Clin. Investigation, 31: 644, 1952.
  • 15. Pullman N. T., Alving A. S. Malignant Hypertension. Medical Clinics of North America, Jan 1951.
  • 16. Reubi F. C. Renal Hyperemia Induced in Man by a New Phthalazine Derivative. Proc. Soc. Exp. Biol. Med., 73: 102, 1950.
  • 17. Schroeder H. A. The Effect of 1-Hydrazinophthalazine in Hypertension. Circulation, 5: 28, 1952.
  • 18. Schroeder M. A. Effects of Hexamethonium Chloride and 1-Hydrazinophthalazine in Hypertension. J. Lab. Clin. Med., 38: 949, 1951.
  • 19. Schroeder H. A. The Control of Hypertension by Hexamethonium and 1-Hydrazinophthalazine: Preliminary Observations. Arch. Intern. Med., 89: 523, 1952.
  • 20. Schroeder H. A., Horrow J. D. The Control of Arterial Hypertension by Hyphex with an Evaluation of Other Methods of Therapy. Med. Clin. North Am., July 1953.
  • 21. Wakerlin G. E. Pathogenesis and Treatment of Essential Hypertension. Med. Clin. North Am., Jan 1953.
  • 22. Wilkins R. W. Hypertension: Recent Trends in Treatment. Med. Clin. North Am., Sept 1953.
  • 23. Wilkinson E. E., Backman H., Hechi H. H. Cardiovascular and Renal Adjustments by a Hypotensive Agent. J. Clin. Investigation, 31: 819, 1952.
  • 24. Wolferth C. C. Observations upon the Management of Arterial Hypertension. Med. Clin. North Am., Nov 1953.

The Role of Antihypertensive Drugs in the Treatment of Essential Hypertension

Year 1959, Volume: 12 Issue: 3-4, 22 - 35, 31.12.1959
https://izlik.org/JA64BJ56DS

Abstract

This study investigates the role of antihypertensive drugs in the treatment of essential hypertension through clinical case evaluations. Seventeen patients were followed long-term, two of whom had malignant hypertension accompanied by renal failure. The study emphasizes the importance of selecting the appropriate antihypertensive agents based on the clinical status of the patient and highlights the potential dangers of sudden blood pressure drops. While positive outcomes were observed in certain patient groups, especially those without complications, the prognosis remained unchanged in malignant hypertension cases.

References

  • 1. Freis D. E. Recent Developments in the Treatment of Hypertension. The Medical Clinics of North America, March 1954.
  • 2. Freis E. D. and Others. The Hemodynamic Effects of Hexamethonium in Man. J. Clin. Investigation, 31: 629, 1957.
  • 3. Freis E. D., Finnerty F. A. Jr., Schnaper H. W., Johnson R. E. The Treatment of Hypertension with Hexamethonium. Circulation, 5: 20, 1952.
  • 4. Frank A., Finnerty Jr. M.D. The Use of 1-Hydrazinophthalazine (Apresoline) in the Management of Hypertension Appearing in Early Pregnancy. The American Journal of Medical Sciences, 222: 140, 1954.
  • 5. Goodman L. E., Gilman A. The Pharmacological Basis of Therapeutics, 2nd Edition, Macmillan Co, 1955, pp. 747–757; 633–638.
  • 6. Hafkenschiel J. H. Newer Drugs in Treatment of Hypertension. Advances in Medicine and Surgery, Univ. of Pennsylvania, W.B. Saunders Co., 1952.
  • 7. Kempner W. Treatment of Hypertensive Vascular Disease with Rice Diet. Am. J. Med., 4: 545–577, 1948.
  • 8. Hoobler S. W., Corley R. W., Kabza T. G., Loyke H. F. Treatment of Hypertension with Oral Protoveratrine. Ann. Intern. Med., 37: 465, 1952.
  • 9. Meilman E., Krayer O. Clinical Studies on Veratrum Alkaloids II. The Dose Response Relationship of Protoveratrine in Hypertension. Circulation, 6: 212, 1952.
  • 10. Merril H. D. Apresoline in the Treatment of Hypertensive Disease: A Clinical Trial with a Control Group. Am. J. Med. Sci., Dec 1953, p. 623.
  • 11. Moyer J. H. Intramuscular Veriloid as a Hypotensive Agent. Am. J. Med. Sci., Nov 1953, p. 477.
  • 12. Moyer J. H. Results with Oral Hexamethonium Alone and in Combination with 1-Hydrazinophthalazine (Apresoline) in Hypertension Therapy. Am. J. Med. Sci., 225: 379, 1953.
  • 13. Moyer J. H., Russel A. H., Handley, Mills L. C. Effect of Hexamethonium Chloride on Cardiovascular and Renal Hemodynamics and Electrolyte Excretion. J. Pharmacol. Exp. Ther., 106(6): 152, 1952.
  • 14. Kirkendall W. M., Culbertson J. W. Some Effects of Hexamethonium on Renal Circulation. J. Clin. Investigation, 31: 644, 1952.
  • 15. Pullman N. T., Alving A. S. Malignant Hypertension. Medical Clinics of North America, Jan 1951.
  • 16. Reubi F. C. Renal Hyperemia Induced in Man by a New Phthalazine Derivative. Proc. Soc. Exp. Biol. Med., 73: 102, 1950.
  • 17. Schroeder H. A. The Effect of 1-Hydrazinophthalazine in Hypertension. Circulation, 5: 28, 1952.
  • 18. Schroeder M. A. Effects of Hexamethonium Chloride and 1-Hydrazinophthalazine in Hypertension. J. Lab. Clin. Med., 38: 949, 1951.
  • 19. Schroeder H. A. The Control of Hypertension by Hexamethonium and 1-Hydrazinophthalazine: Preliminary Observations. Arch. Intern. Med., 89: 523, 1952.
  • 20. Schroeder H. A., Horrow J. D. The Control of Arterial Hypertension by Hyphex with an Evaluation of Other Methods of Therapy. Med. Clin. North Am., July 1953.
  • 21. Wakerlin G. E. Pathogenesis and Treatment of Essential Hypertension. Med. Clin. North Am., Jan 1953.
  • 22. Wilkins R. W. Hypertension: Recent Trends in Treatment. Med. Clin. North Am., Sept 1953.
  • 23. Wilkinson E. E., Backman H., Hechi H. H. Cardiovascular and Renal Adjustments by a Hypotensive Agent. J. Clin. Investigation, 31: 819, 1952.
  • 24. Wolferth C. C. Observations upon the Management of Arterial Hypertension. Med. Clin. North Am., Nov 1953.
There are 24 citations in total.

Details

Primary Language English
Subjects ​Internal Diseases
Journal Section Case Report
Authors

Vehbi Göksel This is me

Publication Date December 31, 1959
IZ https://izlik.org/JA64BJ56DS
Published in Issue Year 1959 Volume: 12 Issue: 3-4

Cite

APA Göksel, V. (1959). The Role of Antihypertensive Drugs in the Treatment of Essential Hypertension. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 12(3-4), 22-35. https://izlik.org/JA64BJ56DS
AMA 1.Göksel V. The Role of Antihypertensive Drugs in the Treatment of Essential Hypertension. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1959;12(3-4):22-35. https://izlik.org/JA64BJ56DS
Chicago Göksel, Vehbi. 1959. “The Role of Antihypertensive Drugs in the Treatment of Essential Hypertension”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 12 (3-4): 22-35. https://izlik.org/JA64BJ56DS.
EndNote Göksel V (December 1, 1959) The Role of Antihypertensive Drugs in the Treatment of Essential Hypertension. Ankara Üniversitesi Tıp Fakültesi Mecmuası 12 3-4 22–35.
IEEE [1]V. Göksel, “The Role of Antihypertensive Drugs in the Treatment of Essential Hypertension”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 12, no. 3-4, pp. 22–35, Dec. 1959, [Online]. Available: https://izlik.org/JA64BJ56DS
ISNAD Göksel, Vehbi. “The Role of Antihypertensive Drugs in the Treatment of Essential Hypertension”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 12/3-4 (December 1, 1959): 22-35. https://izlik.org/JA64BJ56DS.
JAMA 1.Göksel V. The Role of Antihypertensive Drugs in the Treatment of Essential Hypertension. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1959;12:22–35.
MLA Göksel, Vehbi. “The Role of Antihypertensive Drugs in the Treatment of Essential Hypertension”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 12, no. 3-4, Dec. 1959, pp. 22-35, https://izlik.org/JA64BJ56DS.
Vancouver 1.Göksel V. The Role of Antihypertensive Drugs in the Treatment of Essential Hypertension. Ankara Üniversitesi Tıp Fakültesi Mecmuası [Internet]. 1959 Dec. 1;12(3-4):22-35. Available from: https://izlik.org/JA64BJ56DS