Esansiyel Trombositopeni Tedavisinde Kortikosteroidlerle Elde Edilen Klinik Neticeler
Abstract
This study reports the clinical outcomes of corticosteroid therapy in 13 patients with idiopathic thrombocytopenic purpura treated at Ankara University Faculty of Medicine’s II. Internal Medicine Clinic between 1955 and 1960. Patients ranged in age from 13 to 50, with an average of 30 years. Prednisolone was administered in varying dosages (10–50 mg/day). Remission was achieved in 9 cases (69%), particularly in those with a shorter disease duration, suggesting a stronger therapeutic response in acute-stage patients. Corticosteroids effectively elevated platelet counts, reduced hemorrhagic symptoms and negative Lacét results were observed in most remitting cases. The remaining 4 cases showed no clinical improvement. Splenectomy was considered in refractory cases.
Keywords
Idiopathic thrombocytopenia, Purpura, Corticosteroids, Platelet count
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