Aberan Pankreasların Özellikleri (5 Vak’a Münasebetiyle)

Year 1961, Volume: 14 Issue: 2, 129 - 140, 30.06.1961

Ali Ulvi Özkan

https://izlik.org/JA79CP83AU

Abstract

This paper reviews the morphological and clinical features of five cases of aberrant pancreatic tissue, located in the stomach, duodenum, and jejunum. Aberrant pancreas, also known as heterotopic, ectopic, or accessory pancreas, is defined as pancreatic tissue found in non-pancreatic locations without anatomical continuity. These nodules showed variable localization—submucosal, intramuscular, subserosal, or trans-wall involvement—and histology typically revealed exocrine structures (acini and ducts), with one case displaying endocrine islets of Langerhans. Clinical discovery ranged from incidental surgical findings to autopsy. None of the cases showed inflammation, cysts, hemorrhage, necrosis, or neoplastic transformation. Histological examination highlighted adenomyoma-like patterns in muscle layers and differential development based on nodular depth and age. The literature is discussed to contextualize embryological theories, localization frequency, diagnostic challenges, and clinical relevance of aberrant pancreas tissue.

Keywords

Aberrant pancreas , Heterotopic pancreatic tissue , Ectopic pancreas , Accessory pancreas , Embryologic anomaly

Characteristics of Aberrant Pancreatic Tissues (Based on 5 Cases)

https://izlik.org/JA79CP83AU

Abstract

Bu makale, mide, duodenum ve jejunumda lokalize olmuş beş aberan pankreas vak’asının morfolojik ve klinik özelliklerini incelemekte ve konuyla ilgili literatürü değerlendirmektedir. Aberan pankreas; pankreasa anatomik bağlantısı olmayan, farklı organlarda rastlanan pankreas dokusu olarak tanımlanır. Vak’alarda submukozal, intramüsküler, subserozal ve tam duvar tutulumu şeklinde değişik lokalizasyonlar görülmüştür. Histolojik incelemede genellikle ekzokrin yapılara (asini ve kanal) rastlanmış, bir vak’a endokrin Langerhans adacıkları da içermiştir. Klinik olarak bazı vak’alar tesadüfi cerrahi ya da otopsi sırasında tespit edilmiştir. Hiçbirinde ülserasyon, kist, iltihap, kanama, nekroz ya da neoplastik gelişme gözlenmemiştir. Kas tabakalarında adenomiyoma benzeri yapılar izlenmiş, nodül büyüklüğü yaşla orantılı değerlendirilmiştir. Makalede embriyolojik teori, lokalizasyon sıklığı, tanı zorlukları ve klinik önemi kapsamlı şekilde tartışılmıştır.

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