Bir Multiple İdiopathic Sarcoma (Kaposi) Vak’ası

Year 1961, Volume: 14 Issue: 2, 141 - 150, 30.06.1961

Lutfullah Aksungur

Abstract

This paper discusses a case of Kaposi’s sarcoma—a rare vascular neoplasm also known as multiple idiopathic hemorrhagic sarcoma—encountered in a 50-year-old male patient. Over 16 years, the disease manifested as persistent infiltrated plaques on extremities, without nodular transformation. Histopathological evaluation revealed hyperkeratotic epidermis, dermal angiomatous proliferation with newly formed endothelial vessels, mild inflammatory infiltrates, and hemosiderin deposits. The case was notable for intense sciatic-type pain and lack of systemic involvement. The author reviews historical and international literature, discussing the uncertain pathogenesis of Kaposi’s disease, including vascular, neural, reticuloendothelial, and infectious theories. Treatment included high-dose penicillin, with further radiotherapy recommended. The study concludes that Kaposi’s disease is not as rare in Türkiye as previously believed, supported by local statistics.

Keywords

Kaposi , Idiopathic hemorrhagic sarcoma , Vascular neoplasm , Infiltrated plaques , Histopathology , Penicillin therapy

A Case of Multiple Idiopathic Sarcoma (Kaposi)

Abstract

Bu makalede, 50 yaşında erkek hastada görülen Kaposi sarkomu (Morbus Kaposi) vak'ası sunulmuştur. Hastalık 16 yıl boyunca ekstremitelerde enfiltre plaklar şeklinde seyretmiş, nodül oluşumu gözlenmemiştir. Histopatolojik incelemede epidermiste hiperkeratoz, dermiste angiomatöz proliferasyon, yeni endotelyal damar oluşumları, hafif enflamatuvar hücre infiltrasyonu ve yer yer hemosiderin birikimi tespit edilmiştir. Vak’anın özgün yönleri, siyatik benzeri ağrı varlığı ve sistemik tutulum olmamasıdır. Makalede Kaposi hastalığının vasküler, nöral, retiküloendotelyal ve enfeksiyöz menşeleri üzerine görüşler ile tedavi seçenekleri tartışılmıştır. Hastaya yüksek dozda penicillin tedavisi uygulanmış, röntgen tedavisi önerilmiştir. Türkiye’de hastalığın düşünüldüğü kadar nadir olmadığı altı yıllık istatistiklerle vurgulanmıştır.

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