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Self-Administration Of Drugs In Laboratory Animals

Year 1973, Volume: 26 Issue: 2, 463 - 478, 30.06.1973
https://izlik.org/JA59NH22XJ

Abstract

The various technics for self-administration of drugs in laboratory animals have been discussed. The methods for self-administration by oral, inhalation and intravenous routes have been especially emphasized. Table I contains the list of drugs which are self-administrated either by rats or by monkeys. İt is very interesting observation that all drugs listed in this Table Droduce psychological dependence in man.

References

  • 1 — COLLİER, H.O.J.: The Experimental Analysis of Drug-D.ependence. Endeavour 31: 123, 1972.
  • 2 — DENEAU, G.A.: Differences in Addiction and Physiological Depondencc Liability in Animals and Man. Proceedings of the Vtll International Congress of the Collegium Internationale Neuropharmacologicum. Excerpta Medica International Congress Series 129: 121, 1966.
  • 3 — DENEAU, G.A., ve İNOKİ, R : Nicotine Self-Administration in Monkeys. Ann. N.Y. Acad. sci. 142: 277, 1967.
  • 4 — DENEAU, G. A. : Psychogenic Dependence In Monkeys. Scientific Basis of Drtug Dependence, Sahife: 199-207. Editör: H. Steinberg. Churchill Ltd., London, 1969.
  • 5 — DENBAU, G., YANAGÏTA, T. ve SEEVERS, M.H.: Self-administration of Psychoactive Substances by the Monkey. Psychopharmacologia 16 : 30, 1969.
  • 6 — DENEAU, C.A.: Şahsi Görüşme, Birmingham, Alamaba, 1971
  • 7 — DENEAU, G A. ve KAYMAKÇALAN, S.: Physiological and Psychological Dependence to Synthetic A9 -Tetrahydrocannabin01 (THC). Pharmacologist 13: 246. 1971.
  • 8 — FiNDLEY, J.D., ROBINSON. W.W. ve PREGRÏNO.: Addiction to sccoborbital and Chlordiazepoxide in the Rhesus Monkey by Means of a Self-infusion Prefrence Procedure. Psychopharmacologia 26: 93, 1972.
  • 9 — JARVIK, M.E.: Tobacco Smoking in Monkeys. Ann. N.Y. Acad. Sci. 142; 280, 1967.
  • 10 — KAYMAKÇALAN, S. : Physiological and Psychological! dependence on THC in Rhesus Monkeys. Cannabis and its Derivatives, Edit'örler: W.D.M. Paton and June Crown, Sahi!fie: 142. Oxford University Press, London, 1972.
  • 11 — KIELHOLZ, P. ve LADE'WiG, D: Public Health Implications of Recent Development in Drug Dependence, Sahife: 125. Hamrlayanlar: Kaymakgalan, S., Kryspin-Exner, K. , Teigen, A. ve Kielholz, P. Council of Europe, Strasbourg, 1970.
  • 12 — KUMAR, R., STOLERMAN, I.P. ve STEÏNBERG, H.: Resuotion of Morphine Self-administration by Ex - Addict Rats. Agonist and Antagonist Actions of Narcotic Analgesic Drugs, Sažhife: 255. Edtiörler: H. W. Kosterlitz, H.O.J. Collier and J.E. Villarea.l. Macmfflan Press Ltd., Lon don, 1972.
  • 13 — MC EWEN, B. : Alcohol Addiction. Bull. Southern Res. Inst. 20 (No: 1) : 12, 1967.
  • 14 — NiCHOLS, J.R.: A Procedure which Produces Subtained Opiate-directed Behavior (Morphine Addiction) in the Rat, Psychological Report 13: 895, 1963.
  • 15 — NiCHOLS, J.R. ve HSiAO, S.: Addiction Liability of Albino Ats: ding for Quantitative Differences in Morphine Drinking. Science 157 : 561, 1967.
  • 16 — SCHUSTER, C.R. ve THOPSON, T.: Self-Administration of and Behavioral Dependence on Drugs. Ann. Rev. Pharmacol. 9: 483, 1969.
  • 17 — SCHUSTER, C.R.: Psychological Approchcs to Opiate Dependence and Self-Administration by Laboratory Anilmals. Fed, Proc. 29: 2, 1970.
  • 18 — SCHUSTTER, C.R. ve BLASTER, R.L.: Self-Administ,ra.tion of Agonists. Agonist and Antagonist Actions of Narcotic Analgesic Drugs, Sahifc : 243. Editörler: H.W H.O.J. Collier and J.E. Willarreal. Macmillan Press Ltd., London, 1972.
  • 19 — SEEVERS, M.H.: Şahsi Görüşme, Ankara, 1972 20 — SOLOMON, J., DOT, RANDÏ, PHOEBE and FRtEDA.: The Sciences 11 (No: 6) : 22, 1971.
  • 21 — STOLERMA.N, I.P. R. KUMAR.: for Morphine in Rats: Validation of an Experimental Model of Dependence. Psychopharmacologia: 11: 137, 1970.
  • 22 — TALLEY, WT. ve ROSENBLUM, 1.: Self-Adminis•tration of Dextroxyphene by Rhesus Monkeys to the Point of Toxicity. Psychopharmacologia 27: 179, 1972.
  • 23 — ThOMPSON, T. ve SCHUSTER, C.R.: Morphine Self-Administration, Food Reinforced and Avoidance Behavior in Rhesus Monkeys. Psychopharmacologia 5: 87, 1964.
  • 24 — THOMPSON, T.: Drugs as Reinforcers: Experimental Addiction. Int. Addict. 3: 199, 1968.
  • 25 — THOMPSON, T. PICKENS, R : Drug Self-Adrnillistration and Conditioning. Scientific Basis of Drug Dependence, Sahife: 177, Editör: H. Steinberg. Churchill, London, 1969.
  • 26 — THOMPSON, T. ve PICKENS, R.: Stimulant Self-Administration by Animals: Some Comparisons with Opiate Self-Administration. Fed. Proc. 29: 6, 1970.
  • 27 — WEEKS, JR.: Self-Maintained Morphinc "Addiction". A Method for Chronic Programmed Intravenous Injections in Unrestricted Rats. Fed. Proc. 20: 397, 1961.
  • 28 — WEEKS, J.R. ve COLLÏNS, R.J.: Factors Affecting Voluntary Morphine Intake in Self-Maintained Addicted Rats. Psychopharmacologia 6: 267, 1964.
  • 29 — WEEKS, J.R.: Self-Administration Studies in Animal's. Narcotic Drugs. Biochemical Pharmacology, Sahife: 449. Editör: D.H. Clouet. Plenum Press, New York, London, 1971.
  • 30 — WIKLER, A, ve PESCOR, F.T.: Classical Conditioning of a Morphine Abstinence Phenomenon, Reinforcement of Opiod-Drinking Behavior and "Relapse"' in Morphine-Addicted Rats.
  • 31 — WOODS, J.H. ve SHUSTER, C.R.: Regulation of Drug Self-Administration. Drug Dependence, Sahlfe: 158. Editör: R.I. Harris, W.M. Mclsaac ve C.R. Shuster, Jr. University of Texas Press, 1970.
  • 32 — YANAGiTA, T, DENEAU, G.A. ve SEEVERS, M.H.: Evaluation of Pharmacologic Agents in the Monkey by Long Term Intravenous Self or Programmed Administration. Sahife: 453. Excerpta Mediua International Congress Series No. 87, 1965.
  • 33 — YANAGiTA, T. : A Technique for Self-Administratlon of Water Insoluble Drugs to Monkeys by Means of Chronically Implanted Stomach Catheters. Reported to the Committee on Problems of Drug Dependence 1968. Appendix: 39.

Deney Hayvanlarında İlaçların Self-Administrasyonu

Year 1973, Volume: 26 Issue: 2, 463 - 478, 30.06.1973
https://izlik.org/JA59NH22XJ

Abstract

Deney hayvanlarında ilaçların self-administrasyonu metodları gözden geçirilmiş ve bilhassa per oral, inhalasyon ve intravenöz yollarla yapılan self-administrasyon teknikleri üzerinde durulmuştur. Sıçan ve maymunların kendilerine tatbik ettikleri maddelerle, tatbikten hoşlanmadıkları maddeler Tablo: I ve Tablo: II de gösterilmiştir. Tablo: I deki maddelerin hepsine karşı insanda da psişik dependens teşekkülü ilgi çekicidir.
Not : Bu yazıda temas olunan şahsî bulgular ve resimler, yazarın 1971 yılında ABD. de Alabama Eyaletinde Birmingham Şehrinde Southern Pescarch Institute'de Dr. G.A. Deneau'nun labratuarındaki çalışmaları ile ilgilidir.

References

  • 1 — COLLİER, H.O.J.: The Experimental Analysis of Drug-D.ependence. Endeavour 31: 123, 1972.
  • 2 — DENEAU, G.A.: Differences in Addiction and Physiological Depondencc Liability in Animals and Man. Proceedings of the Vtll International Congress of the Collegium Internationale Neuropharmacologicum. Excerpta Medica International Congress Series 129: 121, 1966.
  • 3 — DENEAU, G.A., ve İNOKİ, R : Nicotine Self-Administration in Monkeys. Ann. N.Y. Acad. sci. 142: 277, 1967.
  • 4 — DENEAU, G. A. : Psychogenic Dependence In Monkeys. Scientific Basis of Drtug Dependence, Sahife: 199-207. Editör: H. Steinberg. Churchill Ltd., London, 1969.
  • 5 — DENBAU, G., YANAGÏTA, T. ve SEEVERS, M.H.: Self-administration of Psychoactive Substances by the Monkey. Psychopharmacologia 16 : 30, 1969.
  • 6 — DENEAU, C.A.: Şahsi Görüşme, Birmingham, Alamaba, 1971
  • 7 — DENEAU, G A. ve KAYMAKÇALAN, S.: Physiological and Psychological Dependence to Synthetic A9 -Tetrahydrocannabin01 (THC). Pharmacologist 13: 246. 1971.
  • 8 — FiNDLEY, J.D., ROBINSON. W.W. ve PREGRÏNO.: Addiction to sccoborbital and Chlordiazepoxide in the Rhesus Monkey by Means of a Self-infusion Prefrence Procedure. Psychopharmacologia 26: 93, 1972.
  • 9 — JARVIK, M.E.: Tobacco Smoking in Monkeys. Ann. N.Y. Acad. Sci. 142; 280, 1967.
  • 10 — KAYMAKÇALAN, S. : Physiological and Psychological! dependence on THC in Rhesus Monkeys. Cannabis and its Derivatives, Edit'örler: W.D.M. Paton and June Crown, Sahi!fie: 142. Oxford University Press, London, 1972.
  • 11 — KIELHOLZ, P. ve LADE'WiG, D: Public Health Implications of Recent Development in Drug Dependence, Sahife: 125. Hamrlayanlar: Kaymakgalan, S., Kryspin-Exner, K. , Teigen, A. ve Kielholz, P. Council of Europe, Strasbourg, 1970.
  • 12 — KUMAR, R., STOLERMAN, I.P. ve STEÏNBERG, H.: Resuotion of Morphine Self-administration by Ex - Addict Rats. Agonist and Antagonist Actions of Narcotic Analgesic Drugs, Sažhife: 255. Edtiörler: H. W. Kosterlitz, H.O.J. Collier and J.E. Villarea.l. Macmfflan Press Ltd., Lon don, 1972.
  • 13 — MC EWEN, B. : Alcohol Addiction. Bull. Southern Res. Inst. 20 (No: 1) : 12, 1967.
  • 14 — NiCHOLS, J.R.: A Procedure which Produces Subtained Opiate-directed Behavior (Morphine Addiction) in the Rat, Psychological Report 13: 895, 1963.
  • 15 — NiCHOLS, J.R. ve HSiAO, S.: Addiction Liability of Albino Ats: ding for Quantitative Differences in Morphine Drinking. Science 157 : 561, 1967.
  • 16 — SCHUSTER, C.R. ve THOPSON, T.: Self-Administration of and Behavioral Dependence on Drugs. Ann. Rev. Pharmacol. 9: 483, 1969.
  • 17 — SCHUSTER, C.R.: Psychological Approchcs to Opiate Dependence and Self-Administration by Laboratory Anilmals. Fed, Proc. 29: 2, 1970.
  • 18 — SCHUSTTER, C.R. ve BLASTER, R.L.: Self-Administ,ra.tion of Agonists. Agonist and Antagonist Actions of Narcotic Analgesic Drugs, Sahifc : 243. Editörler: H.W H.O.J. Collier and J.E. Willarreal. Macmillan Press Ltd., London, 1972.
  • 19 — SEEVERS, M.H.: Şahsi Görüşme, Ankara, 1972 20 — SOLOMON, J., DOT, RANDÏ, PHOEBE and FRtEDA.: The Sciences 11 (No: 6) : 22, 1971.
  • 21 — STOLERMA.N, I.P. R. KUMAR.: for Morphine in Rats: Validation of an Experimental Model of Dependence. Psychopharmacologia: 11: 137, 1970.
  • 22 — TALLEY, WT. ve ROSENBLUM, 1.: Self-Adminis•tration of Dextroxyphene by Rhesus Monkeys to the Point of Toxicity. Psychopharmacologia 27: 179, 1972.
  • 23 — ThOMPSON, T. ve SCHUSTER, C.R.: Morphine Self-Administration, Food Reinforced and Avoidance Behavior in Rhesus Monkeys. Psychopharmacologia 5: 87, 1964.
  • 24 — THOMPSON, T.: Drugs as Reinforcers: Experimental Addiction. Int. Addict. 3: 199, 1968.
  • 25 — THOMPSON, T. PICKENS, R : Drug Self-Adrnillistration and Conditioning. Scientific Basis of Drug Dependence, Sahife: 177, Editör: H. Steinberg. Churchill, London, 1969.
  • 26 — THOMPSON, T. ve PICKENS, R.: Stimulant Self-Administration by Animals: Some Comparisons with Opiate Self-Administration. Fed. Proc. 29: 6, 1970.
  • 27 — WEEKS, JR.: Self-Maintained Morphinc "Addiction". A Method for Chronic Programmed Intravenous Injections in Unrestricted Rats. Fed. Proc. 20: 397, 1961.
  • 28 — WEEKS, J.R. ve COLLÏNS, R.J.: Factors Affecting Voluntary Morphine Intake in Self-Maintained Addicted Rats. Psychopharmacologia 6: 267, 1964.
  • 29 — WEEKS, J.R.: Self-Administration Studies in Animal's. Narcotic Drugs. Biochemical Pharmacology, Sahife: 449. Editör: D.H. Clouet. Plenum Press, New York, London, 1971.
  • 30 — WIKLER, A, ve PESCOR, F.T.: Classical Conditioning of a Morphine Abstinence Phenomenon, Reinforcement of Opiod-Drinking Behavior and "Relapse"' in Morphine-Addicted Rats.
  • 31 — WOODS, J.H. ve SHUSTER, C.R.: Regulation of Drug Self-Administration. Drug Dependence, Sahlfe: 158. Editör: R.I. Harris, W.M. Mclsaac ve C.R. Shuster, Jr. University of Texas Press, 1970.
  • 32 — YANAGiTA, T, DENEAU, G.A. ve SEEVERS, M.H.: Evaluation of Pharmacologic Agents in the Monkey by Long Term Intravenous Self or Programmed Administration. Sahife: 453. Excerpta Mediua International Congress Series No. 87, 1965.
  • 33 — YANAGiTA, T. : A Technique for Self-Administratlon of Water Insoluble Drugs to Monkeys by Means of Chronically Implanted Stomach Catheters. Reported to the Committee on Problems of Drug Dependence 1968. Appendix: 39.
There are 32 citations in total.

Details

Primary Language Turkish
Subjects Pharmacology and Pharmaceutical Sciences (Other)
Journal Section Research Article
Authors

Şükrü Kaymakçalan This is me

Publication Date June 30, 1973
IZ https://izlik.org/JA59NH22XJ
Published in Issue Year 1973 Volume: 26 Issue: 2

Cite

APA Kaymakçalan, Ş. (1973). Deney Hayvanlarında İlaçların Self-Administrasyonu. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 26(2), 463-478. https://izlik.org/JA59NH22XJ
AMA 1.Kaymakçalan Ş. Deney Hayvanlarında İlaçların Self-Administrasyonu. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1973;26(2):463-478. https://izlik.org/JA59NH22XJ
Chicago Kaymakçalan, Şükrü. 1973. “Deney Hayvanlarında İlaçların Self-Administrasyonu”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 26 (2): 463-78. https://izlik.org/JA59NH22XJ.
EndNote Kaymakçalan Ş (June 1, 1973) Deney Hayvanlarında İlaçların Self-Administrasyonu. Ankara Üniversitesi Tıp Fakültesi Mecmuası 26 2 463–478.
IEEE [1]Ş. Kaymakçalan, “Deney Hayvanlarında İlaçların Self-Administrasyonu”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 26, no. 2, pp. 463–478, June 1973, [Online]. Available: https://izlik.org/JA59NH22XJ
ISNAD Kaymakçalan, Şükrü. “Deney Hayvanlarında İlaçların Self-Administrasyonu”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 26/2 (June 1, 1973): 463-478. https://izlik.org/JA59NH22XJ.
JAMA 1.Kaymakçalan Ş. Deney Hayvanlarında İlaçların Self-Administrasyonu. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1973;26:463–478.
MLA Kaymakçalan, Şükrü. “Deney Hayvanlarında İlaçların Self-Administrasyonu”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 26, no. 2, June 1973, pp. 463-78, https://izlik.org/JA59NH22XJ.
Vancouver 1.Kaymakçalan Ş. Deney Hayvanlarında İlaçların Self-Administrasyonu. Ankara Üniversitesi Tıp Fakültesi Mecmuası [Internet]. 1973 June 1;26(2):463-78. Available from: https://izlik.org/JA59NH22XJ