Research Article
BibTex RIS Cite

Side Effects And Immunological Aspects of Antibiotics

Year 1973, Volume: 26 Issue: 2, 490 - 510, 30.06.1973
https://izlik.org/JA64GE47FC

Abstract

The side effects of the principal antibiotics and immunological aspects were presented as following:
1) First, side effect of antibiotics were classified.
2) Differences between idiosynchrasy and allergic reactions,
3) Mechanism of gaining antigenicity of drugs,
4) Immunological mechanisms of acute pilergic reactions.
5) Clinical and immunological asoects of contact dermatitis.
6) Phototoxic and photoallergic reaction mechanism of drugs.
7) Resultson the experiments of penicillin were also presented.

References

  • 1 — ACKROYD, J. T. and ROOK, J. : Drug reactions. Clinical Aspects of Immunology. Blackwel Scientific Publicat. 1963.
  • 2 — CRIEP, L.H.: Clinical Immunology and Allergy secand. Edit. 1969.
  • 3 — FEINBERG, s.M., and FEINBERG, A.R.: Allergy to penicillin J. 'Amer. Med. Ass. 160, 778, 1956. 4. — BİERLEÌN, K.J.: Repeated anaphylactic reactions in apatient hinghly sensitized to penicillin. Ann. Allergy 14. 35, 1956.
  • 5 — CROFTON, J. : Desensitization to streptomycin and P.A.S. Brit. Med. T. 2: 759, 1953.
  • 6 — ROSE, B. : Allergic reactions to penicillin; a panel discussion. J. Allergy 24: 383, 1953.
  • 7 — SHELLESJ, W.B. and JUHLÏN, L. : A new test for detecting anaphylactic sensitivity: The basophil neaction Nature 191: 1056, 1961.
  • 8 WATSON, K.c„ JOUBERT s.M. and BENNET M.A.E.: Penicillin a.s a antigen. Nature 183: 468, 1959.
  • 9 — WATSON, K.c., JOUBERT SM. and BENNET, M.A.E.: The occurence of hemagglutinating antibody to pencillin. Immunology 3: 1-12, 1960.
  • 10 — JİLLSON, o.F. and CURVEN, W.L.: Phototoxicity, photo allergy and photosktn tests. Arch. Dermsyph. 80: 678, 1959.
  • 11 — KERN, R.A.: Anaphlylactic drug reactions. Their diagnosis, prevention and treatment. J.A.M.A. 179: 19, 1962.
  • 12 — LERİNE, B.B.: Immunologic mechanisms of penicillin allergy. N. Eng. J. Med. 275: 1115, 1966.
  • 13 — LEVÍNE, B.B.: Studies on the immunologic mechanism of the formatiðn of penicillin antigen. Il. Antigenic specifities of allergic Wheal-and flare skin responses in patients with histories of penicillin allergy. Immunology 7: 542, 1964.
  • 14 — SHELLY, W.B.: Indirect basophili degranulation test for allergy to peniclllin and other drugs J,A.M.A. .184: 171, 1963.
  • 15 — DE WECK, AL. and EÏSEN, H.N.: Some immunochemical properties of penicilenic acid. An antigenic departement derived from penicillin. J. Exp. Med. 112: 1227, 1960.
  • 16 — Penicillin encephalopathy. Brit Med. J. (Editarial) 2: 384, 1967.
  • 17 — WATSON, K.c., JOUBERT, S M. and BENNET, M.A.: Some factors influencing the hemajglutination of penicilMn-sensitized erythrocytes. 4: 193, 1961.
  • 18 — LEWIS, J.E., NELSON, J.C. and ELDER. H.A.: of antibiotic gentamicin Nature New Biol. 1972 (From Excerpta Medica Micbiol. Sec. 26-4, 1296.
  • 19 — BEUTLER, E. : The hemolytic effect of Primagulne and related compound. Blood 14: 103, 1959.
  • 20 — HUMPHREY, J.H. and WHïTE, R.G.•. Immunology for studets of Medicine. Blackwell scintific Publication. 1970.
  • 21 — RÍOTT, I. : Essential Immunology, Black well scientific Publications oxford, London, 1970.
  • 22 — KAGAN, B. : Antimicrobial Therapy, W.B. Saunders co. Philadelphia, 1970.
  • 23 — Fundamentals of Modern Allergy.
  • 24 — THÏERS, H.: Manuel D. Allergologie, 1964, Masson ct Cîe Editeurs, 120. Boulevard Saint Germain, Paris - VI.
  • 25 — SHELDON, J. : et al. Clinical Allergy W.B. Saunders co. Philadelphia 1967 - 177.
  • 26 — QUENG, I.J. and McGOVERN, J.P.: Antigenicity of tetracyclines. J. A1lergy 36: 505, 1965.
  • 27 — KUNïN, C.M., DORNBUCH, A.c., and FïNLAND, Distrubution and Excvetion of four Tetracycline Analogues in Normal yang Meu, C. Cl. Invest. 38: 195, 1959.
  • 28 — WAGELÏE, R.G., DUKES, C.D. and McGOVERN, J.P.: Antigenicity and Cross Reactivity of 6-Aminopenicillanic acid and Penicillin G. J. Allergy 34: 489, 1963.
  • 29 — PACK, s.M. and FELMAN, FF.: Sensitiviti reaction to Aureomycin. J.A.M.A. 142: 1137, 1950.
  • 30 — KUTSCHER, A.H., BUDOWSKY, J.M., LANE, L.L., and CHÏLTON, N.W.: Reactions Following the use of Terramycin trochres: a controlled Study. J. Allergy 23: 177, 1952.
  • 31 — SVEHAG, S. : Antibody formation jn vitro by scparetcd spleren cells inhibition by actinomycin or chloramphenicol science, 146, 659, 1964.
  • 32 — WEÍSBERGER, A.s., DANÍEL, T. and HOFFMAN, A.J.: Suppression of antibody synthesis and prolongation of homograft survival by chloramphenicol J. Exp. Med. 120: 183, 1964.
  • 33 — BRIDGES, R.A., DILLON, H.c. Jr. and GOOD, R.A.: Acute erythroblastopenia due to chloramphenicol A.M.A.J. Discihild, 96: 508, 1958.
  • 34 — CLAUDON, D.B., and HOLBROOK, H.A.: Fatal aplastic anemia associated chloramphenicol therapy J.A.M.A., 149; 912, 1952.
  • 35 — CONE, T.E. and ABELSON, S.M.: Aplastic anemia following two days of chloramphenicol therapy J. Pediat 41: 340, 1952.
  • 36 — POULTO, E.M.: Thrombocytopenic purpura during chloramphenicol therapy Brit. Med. J., 2: 196, 1955.
  • 37 — ROGERS, A.L. and at al.: Neomycin induced steatorrhea, J. A.M. A. , 197: 185, 1966.
  • 38 — POHLMANN, G. : Respiratory arrest assouiated with I.V. administration op polymxin B. sulfate, J.A.M.A. 196: 181, 1966.
  • 39 — ANDERSON, D.W. : Griscofulvin: Biology and clinical usefulness. Ann. Allergy, 23: 103, 1965.

Antibiyotiklerin Yan Etkileri Ve İmmunolojik Veçheleri

Year 1973, Volume: 26 Issue: 2, 490 - 510, 30.06.1973
https://izlik.org/JA64GE47FC

Abstract

Başlıca antibiyotiklerin yan etkileri ve immunolojik veçheleri aşağıdaki şekilde sunuldu :
1) Önce antibiyotiklerin yan etkileri sınıflandırıldı,
2) İdiosenkrazik ve allerjik reaksiyonlar arasındaki farklar,
3) Drug'ların antijenisitesi,
4) Akut allerjik reaksiyonların immunolojik mekanizması,
5) Kontakt dermatitin klinik ve immunolojik veçheleri,
6) İlâçların fototoksik ve fotoallerjik reaksiyonlarının mekanizmaları,
7) Penicillin deneylerine ait sonuçlar da, keza sunuldu

References

  • 1 — ACKROYD, J. T. and ROOK, J. : Drug reactions. Clinical Aspects of Immunology. Blackwel Scientific Publicat. 1963.
  • 2 — CRIEP, L.H.: Clinical Immunology and Allergy secand. Edit. 1969.
  • 3 — FEINBERG, s.M., and FEINBERG, A.R.: Allergy to penicillin J. 'Amer. Med. Ass. 160, 778, 1956. 4. — BİERLEÌN, K.J.: Repeated anaphylactic reactions in apatient hinghly sensitized to penicillin. Ann. Allergy 14. 35, 1956.
  • 5 — CROFTON, J. : Desensitization to streptomycin and P.A.S. Brit. Med. T. 2: 759, 1953.
  • 6 — ROSE, B. : Allergic reactions to penicillin; a panel discussion. J. Allergy 24: 383, 1953.
  • 7 — SHELLESJ, W.B. and JUHLÏN, L. : A new test for detecting anaphylactic sensitivity: The basophil neaction Nature 191: 1056, 1961.
  • 8 WATSON, K.c„ JOUBERT s.M. and BENNET M.A.E.: Penicillin a.s a antigen. Nature 183: 468, 1959.
  • 9 — WATSON, K.c., JOUBERT SM. and BENNET, M.A.E.: The occurence of hemagglutinating antibody to pencillin. Immunology 3: 1-12, 1960.
  • 10 — JİLLSON, o.F. and CURVEN, W.L.: Phototoxicity, photo allergy and photosktn tests. Arch. Dermsyph. 80: 678, 1959.
  • 11 — KERN, R.A.: Anaphlylactic drug reactions. Their diagnosis, prevention and treatment. J.A.M.A. 179: 19, 1962.
  • 12 — LERİNE, B.B.: Immunologic mechanisms of penicillin allergy. N. Eng. J. Med. 275: 1115, 1966.
  • 13 — LEVÍNE, B.B.: Studies on the immunologic mechanism of the formatiðn of penicillin antigen. Il. Antigenic specifities of allergic Wheal-and flare skin responses in patients with histories of penicillin allergy. Immunology 7: 542, 1964.
  • 14 — SHELLY, W.B.: Indirect basophili degranulation test for allergy to peniclllin and other drugs J,A.M.A. .184: 171, 1963.
  • 15 — DE WECK, AL. and EÏSEN, H.N.: Some immunochemical properties of penicilenic acid. An antigenic departement derived from penicillin. J. Exp. Med. 112: 1227, 1960.
  • 16 — Penicillin encephalopathy. Brit Med. J. (Editarial) 2: 384, 1967.
  • 17 — WATSON, K.c., JOUBERT, S M. and BENNET, M.A.: Some factors influencing the hemajglutination of penicilMn-sensitized erythrocytes. 4: 193, 1961.
  • 18 — LEWIS, J.E., NELSON, J.C. and ELDER. H.A.: of antibiotic gentamicin Nature New Biol. 1972 (From Excerpta Medica Micbiol. Sec. 26-4, 1296.
  • 19 — BEUTLER, E. : The hemolytic effect of Primagulne and related compound. Blood 14: 103, 1959.
  • 20 — HUMPHREY, J.H. and WHïTE, R.G.•. Immunology for studets of Medicine. Blackwell scintific Publication. 1970.
  • 21 — RÍOTT, I. : Essential Immunology, Black well scientific Publications oxford, London, 1970.
  • 22 — KAGAN, B. : Antimicrobial Therapy, W.B. Saunders co. Philadelphia, 1970.
  • 23 — Fundamentals of Modern Allergy.
  • 24 — THÏERS, H.: Manuel D. Allergologie, 1964, Masson ct Cîe Editeurs, 120. Boulevard Saint Germain, Paris - VI.
  • 25 — SHELDON, J. : et al. Clinical Allergy W.B. Saunders co. Philadelphia 1967 - 177.
  • 26 — QUENG, I.J. and McGOVERN, J.P.: Antigenicity of tetracyclines. J. A1lergy 36: 505, 1965.
  • 27 — KUNïN, C.M., DORNBUCH, A.c., and FïNLAND, Distrubution and Excvetion of four Tetracycline Analogues in Normal yang Meu, C. Cl. Invest. 38: 195, 1959.
  • 28 — WAGELÏE, R.G., DUKES, C.D. and McGOVERN, J.P.: Antigenicity and Cross Reactivity of 6-Aminopenicillanic acid and Penicillin G. J. Allergy 34: 489, 1963.
  • 29 — PACK, s.M. and FELMAN, FF.: Sensitiviti reaction to Aureomycin. J.A.M.A. 142: 1137, 1950.
  • 30 — KUTSCHER, A.H., BUDOWSKY, J.M., LANE, L.L., and CHÏLTON, N.W.: Reactions Following the use of Terramycin trochres: a controlled Study. J. Allergy 23: 177, 1952.
  • 31 — SVEHAG, S. : Antibody formation jn vitro by scparetcd spleren cells inhibition by actinomycin or chloramphenicol science, 146, 659, 1964.
  • 32 — WEÍSBERGER, A.s., DANÍEL, T. and HOFFMAN, A.J.: Suppression of antibody synthesis and prolongation of homograft survival by chloramphenicol J. Exp. Med. 120: 183, 1964.
  • 33 — BRIDGES, R.A., DILLON, H.c. Jr. and GOOD, R.A.: Acute erythroblastopenia due to chloramphenicol A.M.A.J. Discihild, 96: 508, 1958.
  • 34 — CLAUDON, D.B., and HOLBROOK, H.A.: Fatal aplastic anemia associated chloramphenicol therapy J.A.M.A., 149; 912, 1952.
  • 35 — CONE, T.E. and ABELSON, S.M.: Aplastic anemia following two days of chloramphenicol therapy J. Pediat 41: 340, 1952.
  • 36 — POULTO, E.M.: Thrombocytopenic purpura during chloramphenicol therapy Brit. Med. J., 2: 196, 1955.
  • 37 — ROGERS, A.L. and at al.: Neomycin induced steatorrhea, J. A.M. A. , 197: 185, 1966.
  • 38 — POHLMANN, G. : Respiratory arrest assouiated with I.V. administration op polymxin B. sulfate, J.A.M.A. 196: 181, 1966.
  • 39 — ANDERSON, D.W. : Griscofulvin: Biology and clinical usefulness. Ann. Allergy, 23: 103, 1965.
There are 38 citations in total.

Details

Primary Language Turkish
Subjects Pharmaceutical Microbiology, Clinical Microbiology
Journal Section Research Article
Authors

Rasim Cicioğlu This is me

Publication Date June 30, 1973
IZ https://izlik.org/JA64GE47FC
Published in Issue Year 1973 Volume: 26 Issue: 2

Cite

APA Cicioğlu, R. (1973). Antibiyotiklerin Yan Etkileri Ve İmmunolojik Veçheleri. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 26(2), 490-510. https://izlik.org/JA64GE47FC
AMA 1.Cicioğlu R. Antibiyotiklerin Yan Etkileri Ve İmmunolojik Veçheleri. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1973;26(2):490-510. https://izlik.org/JA64GE47FC
Chicago Cicioğlu, Rasim. 1973. “Antibiyotiklerin Yan Etkileri Ve İmmunolojik Veçheleri”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 26 (2): 490-510. https://izlik.org/JA64GE47FC.
EndNote Cicioğlu R (June 1, 1973) Antibiyotiklerin Yan Etkileri Ve İmmunolojik Veçheleri. Ankara Üniversitesi Tıp Fakültesi Mecmuası 26 2 490–510.
IEEE [1]R. Cicioğlu, “Antibiyotiklerin Yan Etkileri Ve İmmunolojik Veçheleri”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 26, no. 2, pp. 490–510, June 1973, [Online]. Available: https://izlik.org/JA64GE47FC
ISNAD Cicioğlu, Rasim. “Antibiyotiklerin Yan Etkileri Ve İmmunolojik Veçheleri”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 26/2 (June 1, 1973): 490-510. https://izlik.org/JA64GE47FC.
JAMA 1.Cicioğlu R. Antibiyotiklerin Yan Etkileri Ve İmmunolojik Veçheleri. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1973;26:490–510.
MLA Cicioğlu, Rasim. “Antibiyotiklerin Yan Etkileri Ve İmmunolojik Veçheleri”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 26, no. 2, June 1973, pp. 490-1, https://izlik.org/JA64GE47FC.
Vancouver 1.Cicioğlu R. Antibiyotiklerin Yan Etkileri Ve İmmunolojik Veçheleri. Ankara Üniversitesi Tıp Fakültesi Mecmuası [Internet]. 1973 June 1;26(2):490-51. Available from: https://izlik.org/JA64GE47FC