Abstract
Between 1957 and 1961, Chlorambucil was administered to 1,000 patients with chronic lymphoid leukemia who were hospitalized at the Ankara University Faculty of Medicine's Second Internal Medicine Clinic. Two of the cases were exceptional; the others were selected from patients who had not received any previous treatment. Both clinical and hematological improvements were observed in the patients after a short 3-5 week course of Chlorambucil administration. Chlorambucil is a safe and effective treatment for chronic lymphoid leukemia.
References
- 1. HADDOW, A.: Experimental and clinical aspects of the action of various carboxylic derivatives in the aromatic nitrogen mustard series, Ciba Symposium on Leukaemia Research, London, Churchill, 1954.
- 2. RENDA, F.: Klinikte myleran tedavisinden elde edilen neticeler, Ankara Üniversitesi Tıp Fakültesi Mecmuası, 14: 101, 1962.
- 3. ULTMANN, J. E., HYMAN, G. A., GELLHORN, A.: Chlorambucil in treatment of chronic lymphocytic leukemia and certain lymphomas, J. A. M. A. 162: 3, 1956.
- 4. BOLLAG, W.: Tierexperimentelle Untersuchungen über die Wirkung einiger Cystostatica auf das Blutbild, Schweiz. med. Wchnschr. 83: 1027, 1953.
- 5. GALTON, D. A. G., ISRAELS, L. G., NABARRO, J. D. N., and TILL, M.: *Clinical trials of p-(Di-2-Chlorethylamino)-phenylbutyric acid (CB 1348) in malignant lymphoma*, Brit. M. J., 2: 1172, 1955.
Abstract
1957-1961 yılları arasında Ankara Üniversitesi Tıp Fakültesi İkinci İç Hastalıkları Kliniğinde yatarak tedavi gören g kronik lenfold lösemi vakasında Chlorambucil tatbik edilmiştir. Vakaların 2 tanesi müstesna diğerleri önceden hiçbir tedâvi görmemiş hastalar arasında seçilmiştir. 3-5 haftalık kısa bir süre ile Chlorambucilin tatbikinden
sonra hastalarda gerek klinik ve gerekse hematolojik bir salâh müşahede edilmiştir. Chlorambucil kronik lenfoid löseminin emin ve müessir bir ilacıdır.
Keywords
References
- 1. HADDOW, A.: Experimental and clinical aspects of the action of various carboxylic derivatives in the aromatic nitrogen mustard series, Ciba Symposium on Leukaemia Research, London, Churchill, 1954.
- 2. RENDA, F.: Klinikte myleran tedavisinden elde edilen neticeler, Ankara Üniversitesi Tıp Fakültesi Mecmuası, 14: 101, 1962.
- 3. ULTMANN, J. E., HYMAN, G. A., GELLHORN, A.: Chlorambucil in treatment of chronic lymphocytic leukemia and certain lymphomas, J. A. M. A. 162: 3, 1956.
- 4. BOLLAG, W.: Tierexperimentelle Untersuchungen über die Wirkung einiger Cystostatica auf das Blutbild, Schweiz. med. Wchnschr. 83: 1027, 1953.
- 5. GALTON, D. A. G., ISRAELS, L. G., NABARRO, J. D. N., and TILL, M.: *Clinical trials of p-(Di-2-Chlorethylamino)-phenylbutyric acid (CB 1348) in malignant lymphoma*, Brit. M. J., 2: 1172, 1955.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Internal Diseases |
| Journal Section | Case Report |
| Authors | |
| Publication Date | February 28, 1962 |
| IZ | https://izlik.org/JA53NF97EA |
| Published in Issue | Year 1962 Volume: 15 Issue: 1 |