Abstract
In 16 cases of essential hypertension with and without complications and in 18 cases of chronic Bright's disease, the surrenal functions were studied by means of measuring cathecolamine, 17 ketosteroid, DHA and 17 hydroxycorticosteroid excretion in the urine. The results obtained in this study, from clinicopathological point of view, indicate that, the cathecolamine excretion is above normal levels in the labil phase of essential hypertension; and in the cases of renal insufficiency, the amount of surrenal hormones excreted in the urine will not be an accurate measurement of surrenal functions.
Keywords
References
- 1-BONGIOVANNI, A. M.: Determination, recovery, identification and renal clearance of conjugated adrena corticoids in human peripheral blood; Proc. Soc. Exper. Biol. and Med., 89: 281, 1955.
- 2. CSORDAS, J.: New steroid in urine in nephrosis; Lancet, 290: 7118, 1960.
- 3. DAUGHADAY, W. H.: The association of 17-OH corticosteroids and 17-OH corticosteroid glucuronides with plasma proteins and the mechanism of corticosteroid excretion; J. Lab. and Clin. Med., 46: 807, 1955.
- 4. DE GENNES, L.. DRICAINE, H.: Le dosage biologique des catecholamines urinaires dans les pheochromocitomes; La Pres. Med., 6733: 83. 1959.
- 5. DE GENNES, L., Mitziez, P.: Les catecholamines urinaires; application des dosage des catechols urinaires libres au depistages du medullo-surrenalome; La Pres. Med., 66136: 805, 1958.
- 6. DELTOUR, G., cournot, L., KOLOĞLU, S.: Epreuves de charge androgenique chez des sujets normaux et chez des sujets atteints de nephrite chronique; La Pres. Med., 50:13: 246, 1951.
- 7. ENGLERT, E. JR., BROWN. H.: Metabolism of free and conjugated 17-hydroxycorticosteroids in subjets with uremia; J. Clin. Endoc., B: 37. 1959.
- 8. HOLTEN, C.: Malignant hypertension with increased secretion of aldosteron and depletion of potassium; Lancet, 6919: 918, 1956.
- 9. KOLOĞLU, S.: Contribution al'etude des derives androgeniques dons certaines maladies hypertensives; Acta Medica Turcica. V:3-4: 179, 1953 ve VIII-4: 7, 1975.
- 10. KOLOGLU, S.: Endokrinoloji: Ankara Tıp Fakültesi yayınlarından. Balkanoğlu matbaası, 1961.
- 11. LARAGH, J. H.: Aldosteronism and arteriel hypertension; The Med. Clin. of North Ame. 4552: 321, 1961.
- 12. MARKS, L. J. The relationship of the renal excretion of adrenal corticoids and variations in renal hemodynamics, J. Clin. Invest. 32: 613. 1953.
- 13. PAGE, I. H.: Production d'une hypertension arterielle persistante par la membrane de cellophane perirenale: JAMA, 113: 2040, 1939.
- 14. SÖKMEN, C.: Dahili böbrek hastalıkları; Ankara Tıp Fakültesi yayınlarından; Güzel sanatlar matbaası, 1961.
- 15. TRONCHETTI, F.: Aldosterone et maladie vasculaire hypertensive; Annales d'Endocr. 1854: 654,1957- 16-VENNING, E. H.: Essential hypertension and aldosterone; Circulation, XXIII: 168, 1961.
Abstract
16 komplikasyonsuz ve komplikasyonlu esasi hipertansiyon vakasında, 18 müzmin böbrek hastalığı (normotansif veya hipertansif nefrit ve nefrotik sendrom) vakasında katekolamin, 17-ketosteroid DHA, 17-hidroksikortikosteroid itrahının tayini ile sürrenal fonksiyonları araştırılmıştır. Elde ettiğimiz neticeler kliniko-patolojik noktai nazardan iki mühim problem aydınlatmıştır: Bunlardan birisi labil safhada esasi hipertansiyon vakalarında katekolamin itrahının normalin üstünde bulunabileceği, diğeri ise böbrek yetersizliği vakalarında sürrenal hormonlarının idrarla itrah edilen miktarlarının sürrenal fonksiyonları hakkında doğru bilgi veremeyeceğidir.
Keywords
References
- 1-BONGIOVANNI, A. M.: Determination, recovery, identification and renal clearance of conjugated adrena corticoids in human peripheral blood; Proc. Soc. Exper. Biol. and Med., 89: 281, 1955.
- 2. CSORDAS, J.: New steroid in urine in nephrosis; Lancet, 290: 7118, 1960.
- 3. DAUGHADAY, W. H.: The association of 17-OH corticosteroids and 17-OH corticosteroid glucuronides with plasma proteins and the mechanism of corticosteroid excretion; J. Lab. and Clin. Med., 46: 807, 1955.
- 4. DE GENNES, L.. DRICAINE, H.: Le dosage biologique des catecholamines urinaires dans les pheochromocitomes; La Pres. Med., 6733: 83. 1959.
- 5. DE GENNES, L., Mitziez, P.: Les catecholamines urinaires; application des dosage des catechols urinaires libres au depistages du medullo-surrenalome; La Pres. Med., 66136: 805, 1958.
- 6. DELTOUR, G., cournot, L., KOLOĞLU, S.: Epreuves de charge androgenique chez des sujets normaux et chez des sujets atteints de nephrite chronique; La Pres. Med., 50:13: 246, 1951.
- 7. ENGLERT, E. JR., BROWN. H.: Metabolism of free and conjugated 17-hydroxycorticosteroids in subjets with uremia; J. Clin. Endoc., B: 37. 1959.
- 8. HOLTEN, C.: Malignant hypertension with increased secretion of aldosteron and depletion of potassium; Lancet, 6919: 918, 1956.
- 9. KOLOĞLU, S.: Contribution al'etude des derives androgeniques dons certaines maladies hypertensives; Acta Medica Turcica. V:3-4: 179, 1953 ve VIII-4: 7, 1975.
- 10. KOLOGLU, S.: Endokrinoloji: Ankara Tıp Fakültesi yayınlarından. Balkanoğlu matbaası, 1961.
- 11. LARAGH, J. H.: Aldosteronism and arteriel hypertension; The Med. Clin. of North Ame. 4552: 321, 1961.
- 12. MARKS, L. J. The relationship of the renal excretion of adrenal corticoids and variations in renal hemodynamics, J. Clin. Invest. 32: 613. 1953.
- 13. PAGE, I. H.: Production d'une hypertension arterielle persistante par la membrane de cellophane perirenale: JAMA, 113: 2040, 1939.
- 14. SÖKMEN, C.: Dahili böbrek hastalıkları; Ankara Tıp Fakültesi yayınlarından; Güzel sanatlar matbaası, 1961.
- 15. TRONCHETTI, F.: Aldosterone et maladie vasculaire hypertensive; Annales d'Endocr. 1854: 654,1957- 16-VENNING, E. H.: Essential hypertension and aldosterone; Circulation, XXIII: 168, 1961.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Internal Diseases, Nefroloji |
| Journal Section | Research Article |
| Authors | |
| Publication Date | April 30, 1962 |
| IZ | https://izlik.org/JA69DA73LG |
| Published in Issue | Year 1962 Volume: 15 Issue: 2 |