DIFFERENT TYPES OF DIET IN RABBITS ANATOMICAL AND HISTOLOGICAL STRUCTURE OF THE THYROID EFFECTS AND IMPACTS. . WHAT IS THE ROLE OF THE «THIOSULFATE» CONTENT OF FOODS IN THIS?

Abstract

We investigated the histologica,l changes of thyroid gland in rabbits submitted to various nutritional patterns : No structural changes were observed in rabbits fed with normal control nutrition combined with 250 gr. of kale (Brassica Oleracea Acephala) or supplemented with 5 pg. of iodine per kg. of body weight per day. Iodine deficient nutrition produced macrofollicular colloid and microfollicular paranchymatous goiter. In rabbits fed simply with 250 gr. of kale per Kg/per day we observed the histologic changes fitting to the paranchymatous goiter. But, with the reduction of this quantity below 100.0 gr. per Kg. per day, a macrofollicular colloid goiter pattern was associated to the microfollicular pattern. Thiocyanate content of the edible part of kale Iwas found to be 11.0+0.3 mg 100 gr. and of milk 1.4+0.08 mg/100 ec. The maximum amounL of kale consumed in the Eastern Black Sea Region in Th-lrkey is 400.0 gr., and of milk is 0.5 liter per person/ per day. The thiocyanate contents of these foods are 44.0 mg. and 7.0 mg. respectively. These quantities of thiocyanate are far below the amount of the thiocyanate showing antithyroid and goitrogen activity in rabbits and in human. Then, in the quantities consumed, the kale and milk can not play a role in the etiology of goiter in the Eastern Black Sea region endemics in Turkey.

Keywords

• thyroid
• thiosulfate
• rabbits

TAVŞANLARDA FARKLI BESLENME TÜRLERİ TİROİDİN ANATOMİK VE HİSTOLOJİK YAPISI ETKİ VE ETKİLERİ. . BUNUN İÇİN GIDALARIN «TİYOSİYANAT» İÇERİĞİNİN ROLÜ NEDİR?

Abstract

6 gurup halinde değişik beslenmelere tabi tutulan tavşanlarda tiroid bezinde husule gelen anatomik ve histolojik değişiklikler incelendi. Bir günde Kg. başına 250 gr. kara lahana (Brassica Oleracea Acephala) eklenmiş normal beslenmeye veya günde Kg. başına 5 pg. iyod ilave edilmiş kara lahana beslenmesine tabi tutulmuş tavşanlarda tiroid bezinde bariz bir histolojik değişiklik tesbit edilmemiştir. Fakat iyoddan fakir bir beslenmeye tabi tutulan tavşanların tinoidinde makrofolliküler kolloid ve mikrofolliküler parankimatöz guvatr'a uyan histolojik değişiklikler müşahede edilmiştir. Günde Kg. başına 250 gr. kara lahana ile beslenen tavşanlarda parankimatöz guvatr teşekkül etmiştir. Bu miktar 100 gr. ın altına indirilince bu değişikliklere, makrofolliküler kolloid guvatra ait değişiklikler eklenmiştir. 100 gr. kara lahana yaprağında 11.0 +0,3 mg. , 100 cc sütte ise 1.4+0.08 mg. thiocyanate tesbit edilmiştir. Bir günde Doğu Karadeniz Bölgesinde yenen 400 gr. Kara lahananm thiocyanate muhteviyatı 44,0 mg. , yarım kg. süt mahsüllerinin thiocyanate muhteviyatı ise 7,0 mg. kadardır. Bu miktar bizim tavşanlarda tesbit ettiğimiz veya literatürde verilen ve tiroid glandı üzerine müessir olan miktarların çok altındadır. Binaenaleyh, Doğu Karadeniz bölgesinde şahıs başına tüketilen kara lahananın, hüküm süren mutedil iyod yetersizliğine rağmen, bu bölgedeki guvatr endemisinin etiyolojisinde her hangi bir rolü bahis konusu olamaz.

Keywords

• tiroit
• tiyosiyanat
• tavşanlar

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