This comprehensive article explores the anatomy, physiology, pathology, and stereotaxic surgical treatment of the extrapyramidal system. It reviews findings from animal studies, neuroanatomical observations, and clinical cases—particularly in Parkinson's disease. Detailed explanations are given for various brain nuclei and pathways (e.g., Locus Niger, Globus Pallidus, Putamen, Nucleus Caudatus) and their role in motor symptoms such as tremor, rigidity, chorea, and athetosis. Multiple pathophysiological theories (Strio-Cerebellar, Gamma Neuron Circuit, Jenkner-Ward, etc.) are discussed alongside surgical outcomes from stereotaxic interventions targeting specific brain regions.
This comprehensive article explores the anatomy, physiology, pathology, and stereotaxic surgical treatment of the extrapyramidal system. It reviews findings from animal studies, neuroanatomical observations, and clinical cases—particularly in Parkinson's disease. Detailed explanations are given for various brain nuclei and pathways (e.g., Locus Niger, Globus Pallidus, Putamen, Nucleus Caudatus) and their role in motor symptoms such as tremor, rigidity, chorea, and athetosis. Multiple pathophysiological theories (Strio-Cerebellar, Gamma Neuron Circuit, Jenkner-Ward, etc.) are discussed alongside surgical outcomes from stereotaxic interventions targeting specific brain regions.
| Primary Language | English |
|---|---|
| Subjects | Neurology and Neuromuscular Diseases |
| Journal Section | Research Article |
| Authors | |
| Publication Date | June 30, 1965 |
| IZ | https://izlik.org/JA86NW65KF |
| Published in Issue | Year 1965 Volume: 18 Issue: 2 |